In vivo CYP3A activity and pharmacokinetics of imatinib in relation to therapeutic outcome in chronic myeloid leukemia patients.
(2016) In Therapeutic Drug Monitoring 38(2). p.230-238- Abstract
- CYP3A metabolic activity varies between individuals and is therefore a possible candidate of influence on the therapeutic outcome of the tyrosine kinase inhibitor imatinib in chronic myeloid leukemia (CML) patients. The aim of this study was to investigate the influence of CYP3A metabolic activity on the plasma concentration and outcome of imatinib in CML patients.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8503946
- author
- organization
- publishing date
- 2016
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Therapeutic Drug Monitoring
- volume
- 38
- issue
- 2
- pages
- 230 - 238
- publisher
- Lippincott Williams & Wilkins
- external identifiers
-
- pmid:26693810
- scopus:84951310669
- pmid:26693810
- ISSN
- 0163-4356
- DOI
- 10.1097/FTD.0000000000000268
- language
- English
- LU publication?
- yes
- id
- 65e40989-194a-4c96-9569-905b0ef3a4bc (old id 8503946)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26693810?dopt=Abstract
- date added to LUP
- 2016-04-04 09:27:26
- date last changed
- 2022-02-21 00:53:23
@article{65e40989-194a-4c96-9569-905b0ef3a4bc, abstract = {{CYP3A metabolic activity varies between individuals and is therefore a possible candidate of influence on the therapeutic outcome of the tyrosine kinase inhibitor imatinib in chronic myeloid leukemia (CML) patients. The aim of this study was to investigate the influence of CYP3A metabolic activity on the plasma concentration and outcome of imatinib in CML patients.}}, author = {{Skoglund, Karin and Richter, Johan and Olsson-Strömberg, Ulla and Bergquist, Jonas and Aluthgedara, Warunika and Ubhayasekera, S J Kumari A and Vikingsson, Svante and Svedberg, Anna and Söderlund, Stina and Sandstedt, Anna and Johnsson, Anders and Aagesen, Jesper and Alsenhed, Jonas and Hägg, Staffan and Peterson, Curt and Lotfi, Kourosh and Gréen, Henrik}}, issn = {{0163-4356}}, language = {{eng}}, number = {{2}}, pages = {{230--238}}, publisher = {{Lippincott Williams & Wilkins}}, series = {{Therapeutic Drug Monitoring}}, title = {{In vivo CYP3A activity and pharmacokinetics of imatinib in relation to therapeutic outcome in chronic myeloid leukemia patients.}}, url = {{http://dx.doi.org/10.1097/FTD.0000000000000268}}, doi = {{10.1097/FTD.0000000000000268}}, volume = {{38}}, year = {{2016}}, }