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Recurrent t(16;17)(q22;p13) in aneurysmal bone cysts

Panoutsakopoulos, Giorgos ; Pandis, Nikos ; Kyriazoglou, Ioannis ; Gustafson, Pelle LU ; Mertens, Fredrik LU and Mandahl, Nils LU (1999) In Genes Chromosomes and Cancer 26(3). p.265-266
Abstract

Aneurysmal bone cyst (ABC) is a benign bone lesion for which no previous cytogenetic data exist. We describe the finding of clonal chromosome aberrations in three tumors; two had a t(16;17)(q22;p13) as the sole anomaly, and the third had a del(16)(q22) as the only change. These findings show that somatic mutations contribute to the development of ABC and furthermore indicate that bands 16q22 and 17p13 may harbor genes of importance in this process.

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author
; ; ; ; and
publishing date
type
Contribution to journal
publication status
published
subject
in
Genes Chromosomes and Cancer
volume
26
issue
3
pages
2 pages
publisher
Wiley-Liss Inc.
external identifiers
  • pmid:10502326
  • scopus:0032835894
ISSN
1045-2257
DOI
10.1002/(SICI)1098-2264(199911)26:3<265::AID-GCC12>3.0.CO;2-%23
language
English
LU publication?
no
id
8505986e-0eef-4bfa-bd01-d075de34abbf
date added to LUP
2019-05-25 07:53:00
date last changed
2025-04-04 14:33:35
@misc{8505986e-0eef-4bfa-bd01-d075de34abbf,
  abstract     = {{<p>Aneurysmal bone cyst (ABC) is a benign bone lesion for which no previous cytogenetic data exist. We describe the finding of clonal chromosome aberrations in three tumors; two had a t(16;17)(q22;p13) as the sole anomaly, and the third had a del(16)(q22) as the only change. These findings show that somatic mutations contribute to the development of ABC and furthermore indicate that bands 16q22 and 17p13 may harbor genes of importance in this process.</p>}},
  author       = {{Panoutsakopoulos, Giorgos and Pandis, Nikos and Kyriazoglou, Ioannis and Gustafson, Pelle and Mertens, Fredrik and Mandahl, Nils}},
  issn         = {{1045-2257}},
  language     = {{eng}},
  month        = {{11}},
  number       = {{3}},
  pages        = {{265--266}},
  publisher    = {{Wiley-Liss Inc.}},
  series       = {{Genes Chromosomes and Cancer}},
  title        = {{Recurrent t(16;17)(q22;p13) in aneurysmal bone cysts}},
  url          = {{http://dx.doi.org/10.1002/(SICI)1098-2264(199911)26:3<265::AID-GCC12>3.0.CO;2-%23}},
  doi          = {{10.1002/(SICI)1098-2264(199911)26:3<265::AID-GCC12>3.0.CO;2-%23}},
  volume       = {{26}},
  year         = {{1999}},
}