A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources.
Leffler, Jonatan LU ; Ciacma, Katarzyna LU ; Gullstrand, Birgitta LU ; Bengtsson, Anders LU ; Martin, Myriam LU and Blom, Anna LU
(2015)
In Arthritis Research and Therapy
17.
- Abstract
- Patients with systemic lupus erythematosus (SLE) have a decreased ability to clear cell remnants and multiple deficiencies in the ability to degrade cellular chromatin have been linked to the disease. Since the discovery of neutrophil extracellular traps (NETs), a renewed interest has been sparked in this field of research with multiple studies reporting a decreased ability of patients with SLE to degrade NETs. In this study we extend these findings by investigating the ability of patients with SLE to degrade chromatin from multiple clinically relevant sources.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/7844085
- author
- Leffler, Jonatan
LU
; Ciacma, Katarzyna
LU
; Gullstrand, Birgitta
LU
; Bengtsson, Anders
LU
; Martin, Myriam
LU
and Blom, Anna
LU
- organization
- publishing date
- 2015
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Arthritis Research and Therapy
- volume
- 17
- article number
- 205
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:26268365
- wos:000359340700001
- scopus:84939178193
- pmid:26268365
- ISSN
- 1478-6362
- DOI
- 10.1186/s13075-015-0726-y
- language
- English
- LU publication?
- yes
- id
- 856f0a4e-929f-4761-9bf0-cb3c4a8ea85c (old id 7844085)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26268365?dopt=Abstract
- date added to LUP
- 2016-04-01 10:49:43
- date last changed
- 2022-04-12 18:07:28
@article{856f0a4e-929f-4761-9bf0-cb3c4a8ea85c,
abstract = {{Patients with systemic lupus erythematosus (SLE) have a decreased ability to clear cell remnants and multiple deficiencies in the ability to degrade cellular chromatin have been linked to the disease. Since the discovery of neutrophil extracellular traps (NETs), a renewed interest has been sparked in this field of research with multiple studies reporting a decreased ability of patients with SLE to degrade NETs. In this study we extend these findings by investigating the ability of patients with SLE to degrade chromatin from multiple clinically relevant sources.}},
author = {{Leffler, Jonatan and Ciacma, Katarzyna and Gullstrand, Birgitta and Bengtsson, Anders and Martin, Myriam and Blom, Anna}},
issn = {{1478-6362}},
language = {{eng}},
publisher = {{BioMed Central (BMC)}},
series = {{Arthritis Research and Therapy}},
title = {{A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources.}},
url = {{https://lup.lub.lu.se/search/files/2165187/8618991}},
doi = {{10.1186/s13075-015-0726-y}},
volume = {{17}},
year = {{2015}},
}