A Synthesis Method for Automatic Handling of Inter-patient Variability in Closed-loop Anesthesia
(2016) American Control Conference, 2016 p.4877-4882- Abstract
- This paper presents a convex-optimization-based technique to obtain parameters for a PID feedback controller, used to control the infusion rate of the anesthetic drug propofol. The controller design is based on a set of identified patient models, relating propofol infusion to an EEG-based conciousness index. The main contribution lies in the method automatically taking inter-patient variability into account, i.e., it guarantees robustness (sensitivity peak) and performance (disturbance rejection) over a set of patient models, without the need for manual intervention. The method is demonstrated using a clinically relevant design example. A controller designed using the proposed method is currently scheduled for clinical evaluation.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8570875
- author
- Soltesz, Kristian LU ; van Heusden, Klaske ; Hast, Martin LU ; Ansermino, J. Mark and Dumont, Guy A.
- organization
- publishing date
- 2016
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- host publication
- Proceedings of the 2016 American Control Conference
- pages
- 4877 - 4882
- publisher
- IEEE - Institute of Electrical and Electronics Engineers Inc.
- conference name
- American Control Conference, 2016
- conference location
- Boston, United States
- conference dates
- 2016-07-06 - 2016-07-08
- external identifiers
-
- scopus:84992159390
- ISBN
- 978-1-4673-8682-1
- DOI
- 10.1109/ACC.2016.7526125
- project
- Anesthesia in Closed Loop
- language
- English
- LU publication?
- yes
- id
- 35d2acdc-c0e0-4d61-8a1d-8c26bfc97065 (old id 8570875)
- date added to LUP
- 2016-04-04 13:46:34
- date last changed
- 2024-06-04 15:07:18
@inproceedings{35d2acdc-c0e0-4d61-8a1d-8c26bfc97065, abstract = {{This paper presents a convex-optimization-based technique to obtain parameters for a PID feedback controller, used to control the infusion rate of the anesthetic drug propofol. The controller design is based on a set of identified patient models, relating propofol infusion to an EEG-based conciousness index. The main contribution lies in the method automatically taking inter-patient variability into account, i.e., it guarantees robustness (sensitivity peak) and performance (disturbance rejection) over a set of patient models, without the need for manual intervention. The method is demonstrated using a clinically relevant design example. A controller designed using the proposed method is currently scheduled for clinical evaluation.}}, author = {{Soltesz, Kristian and van Heusden, Klaske and Hast, Martin and Ansermino, J. Mark and Dumont, Guy A.}}, booktitle = {{Proceedings of the 2016 American Control Conference}}, isbn = {{978-1-4673-8682-1}}, language = {{eng}}, pages = {{4877--4882}}, publisher = {{IEEE - Institute of Electrical and Electronics Engineers Inc.}}, title = {{A Synthesis Method for Automatic Handling of Inter-patient Variability in Closed-loop Anesthesia}}, url = {{https://lup.lub.lu.se/search/files/11244007/final.pdf}}, doi = {{10.1109/ACC.2016.7526125}}, year = {{2016}}, }