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Control of Dissolved Oxygen in Stirred Bioreactors

Åkesson, Mats LU and Hagander, Per LU (1998) In Technical Reports TFRT-7571
Abstract
This report discusses control of dissolved oxygen in a bioreactor where the oxygen supply is manipulated using the stirrer speed. In batch and fed-batch cultivations the operating conditions change significantly which may cause tuning problems. Analysis using a linearized process model shows that the process dynamics is mainly affected by changes in the volumetric oxygen transfer coefficient $K_La$. % To account for the process variations, a control strategy based on PID control and gain scheduling from the stirrer speed is suggested. This approach is straightforward to implement in an industrial control system. Experimental results from a laboratory reactor are presented.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Book/Report
publication status
published
subject
keywords
Feedback control, dissolved oxygen, stirrer speed, bioreactor, gain scheduling.
in
Technical Reports TFRT-7571
publisher
Department of Automatic Control, Lund Institute of Technology (LTH)
ISSN
0280-5316
language
English
LU publication?
yes
id
f3be4419-484f-4bd8-85a5-b233bf67eb2a (old id 8602746)
date added to LUP
2016-02-19 11:13:05
date last changed
2018-07-17 12:54:19
@techreport{f3be4419-484f-4bd8-85a5-b233bf67eb2a,
  abstract     = {This report discusses control of dissolved oxygen in a bioreactor where the oxygen supply is manipulated using the stirrer speed. In batch and fed-batch cultivations the operating conditions change significantly which may cause tuning problems. Analysis using a linearized process model shows that the process dynamics is mainly affected by changes in the volumetric oxygen transfer coefficient $K_La$. % To account for the process variations, a control strategy based on PID control and gain scheduling from the stirrer speed is suggested. This approach is straightforward to implement in an industrial control system. Experimental results from a laboratory reactor are presented.},
  author       = {Åkesson, Mats and Hagander, Per},
  institution  = {Department of Automatic Control, Lund Institute of Technology (LTH)},
  issn         = {0280-5316},
  keyword      = {Feedback control,dissolved oxygen,stirrer speed,bioreactor,gain scheduling.},
  language     = {eng},
  series       = {Technical Reports TFRT-7571},
  title        = {Control of Dissolved Oxygen in Stirred Bioreactors},
  year         = {1998},
}