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Genome-wide Scan Identifies Role for AOX1 in Prostate Cancer Survival

Li, Weiqiang ; Middha, Mridu ; Bicak, Mesude ; Sjoberg, Daniel D. ; Vertosick, Emily ; Dahlin, Anders LU ; Häggström, Christel ; Hallmans, Göran ; Rönn, Ann Charlotte and Stattin, Pär , et al. (2018) In European Urology 74(6). p.710-719
Abstract

We performed genome-wide association studies and found single nucleotide polymorphisms (SNPs) at seven independent loci associated with prostate-cancer-specific survival time. Two SNPs replicated in an independent cohort. The SNP rs73055188 at AOX1 is associated with AOX1 gene expression level, which is correlated with biochemical recurrence.

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@article{8738fe3a-aa6e-4aee-a5c0-5e4b81155eb4,
  abstract     = {<p>We performed genome-wide association studies and found single nucleotide polymorphisms (SNPs) at seven independent loci associated with prostate-cancer-specific survival time. Two SNPs replicated in an independent cohort. The SNP rs73055188 at AOX1 is associated with AOX1 gene expression level, which is correlated with biochemical recurrence.</p>},
  author       = {Li, Weiqiang and Middha, Mridu and Bicak, Mesude and Sjoberg, Daniel D. and Vertosick, Emily and Dahlin, Anders and Häggström, Christel and Hallmans, Göran and Rönn, Ann Charlotte and Stattin, Pär and Melander, Olle and Ulmert, David and Lilja, Hans and Klein, Robert J.},
  issn         = {0302-2838},
  language     = {eng},
  month        = {01},
  number       = {6},
  pages        = {710--719},
  publisher    = {Elsevier},
  series       = {European Urology},
  title        = {Genome-wide Scan Identifies Role for AOX1 in Prostate Cancer Survival},
  url          = {http://dx.doi.org/10.1016/j.eururo.2018.06.021},
  doi          = {10.1016/j.eururo.2018.06.021},
  volume       = {74},
  year         = {2018},
}