Genome-wide Scan Identifies Role for AOX1 in Prostate Cancer Survival
(2018) In European Urology 74(6). p.710-719- Abstract
We performed genome-wide association studies and found single nucleotide polymorphisms (SNPs) at seven independent loci associated with prostate-cancer-specific survival time. Two SNPs replicated in an independent cohort. The SNP rs73055188 at AOX1 is associated with AOX1 gene expression level, which is correlated with biochemical recurrence.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8738fe3a-aa6e-4aee-a5c0-5e4b81155eb4
- author
- organization
- publishing date
- 2018-01-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- AOX1, Expression quantitative trait locus, Genome-wide association study, Prostate cancer, Survival analysis
- in
- European Urology
- volume
- 74
- issue
- 6
- pages
- 710 - 719
- publisher
- Elsevier
- external identifiers
-
- pmid:30289108
- scopus:85049454744
- ISSN
- 0302-2838
- DOI
- 10.1016/j.eururo.2018.06.021
- language
- English
- LU publication?
- yes
- id
- 8738fe3a-aa6e-4aee-a5c0-5e4b81155eb4
- date added to LUP
- 2018-07-26 10:19:54
- date last changed
- 2024-09-17 23:47:54
@article{8738fe3a-aa6e-4aee-a5c0-5e4b81155eb4, abstract = {{<p>We performed genome-wide association studies and found single nucleotide polymorphisms (SNPs) at seven independent loci associated with prostate-cancer-specific survival time. Two SNPs replicated in an independent cohort. The SNP rs73055188 at AOX1 is associated with AOX1 gene expression level, which is correlated with biochemical recurrence.</p>}}, author = {{Li, Weiqiang and Middha, Mridu and Bicak, Mesude and Sjoberg, Daniel D. and Vertosick, Emily and Dahlin, Anders and Häggström, Christel and Hallmans, Göran and Rönn, Ann Charlotte and Stattin, Pär and Melander, Olle and Ulmert, David and Lilja, Hans and Klein, Robert J.}}, issn = {{0302-2838}}, keywords = {{AOX1; Expression quantitative trait locus; Genome-wide association study; Prostate cancer; Survival analysis}}, language = {{eng}}, month = {{01}}, number = {{6}}, pages = {{710--719}}, publisher = {{Elsevier}}, series = {{European Urology}}, title = {{Genome-wide Scan Identifies Role for AOX1 in Prostate Cancer Survival}}, url = {{http://dx.doi.org/10.1016/j.eururo.2018.06.021}}, doi = {{10.1016/j.eururo.2018.06.021}}, volume = {{74}}, year = {{2018}}, }