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High levels of cathepsin D and cystatin B are associated with increased risk of coronary events.

Goncalves, Isabel LU ; Hultman, Karin LU ; Dunér, Pontus LU ; Edsfeldt, Andreas LU ; Hedblad, Bo LU ; Nordin Fredrikson, Gunilla LU ; Björkbacka, Harry LU ; Nilsson, Jan LU and Bengtsson, Eva LU (2016) In Open Heart 3(1). p.000353-000353
Abstract
The majority of acute coronary syndromes are caused by plaque ruptures. Proteases secreted by macrophages play an important role in plaque ruptures by degrading extracellular matrix proteins in the fibrous cap. Matrix metalloproteinases have been shown to be markers for cardiovascular disease whereas the members of the cathepsin protease family are less studied.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Open Heart
volume
3
issue
1
pages
000353 - 000353
publisher
BMJ Publishing Group
external identifiers
  • pmid:26848396
ISSN
2053-3624
DOI
10.1136/openhrt-2015-000353
language
English
LU publication?
yes
id
58eba7e4-e5b9-4c21-b38b-16bf33269b2d (old id 8829220)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26848396?dopt=Abstract
date added to LUP
2016-03-01 14:08:14
date last changed
2016-09-20 03:34:28
@article{58eba7e4-e5b9-4c21-b38b-16bf33269b2d,
  abstract     = {The majority of acute coronary syndromes are caused by plaque ruptures. Proteases secreted by macrophages play an important role in plaque ruptures by degrading extracellular matrix proteins in the fibrous cap. Matrix metalloproteinases have been shown to be markers for cardiovascular disease whereas the members of the cathepsin protease family are less studied.},
  author       = {Goncalves, Isabel and Hultman, Karin and Dunér, Pontus and Edsfeldt, Andreas and Hedblad, Bo and Nordin Fredrikson, Gunilla and Björkbacka, Harry and Nilsson, Jan and Bengtsson, Eva},
  issn         = {2053-3624},
  language     = {eng},
  number       = {1},
  pages        = {000353--000353},
  publisher    = {BMJ Publishing Group},
  series       = {Open Heart},
  title        = {High levels of cathepsin D and cystatin B are associated with increased risk of coronary events.},
  url          = {http://dx.doi.org/10.1136/openhrt-2015-000353},
  volume       = {3},
  year         = {2016},
}