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Confirmation of the Intracoronary Near-Infrared Spectroscopy Threshold of Lipid-Rich Plaques That Underlie ST-Segment-Elevation Myocardial Infarction.

Madder, Ryan D; Puri, Rishi; Muller, James E; Harnek, Jan LU ; Götberg, Matthias LU ; VanOosterhout, Stacie; Chi, Margaret; Wohns, David; McNamara, Richard and Wolski, Kathy, et al. (2016) In Arteriosclerosis, Thrombosis and Vascular Biology 36(5). p.1010-1015
Abstract
In a previous exploratory analysis, intracoronary near-infrared spectroscopy (NIRS) found the majority of culprit lesions in ST-segment-elevation myocardial infarction (STEMI) to contain a maximum lipid core burden index in 4 mm (maxLCBI4mm) of >400. This initial study was limited by a small sample size, enrollment at a single center, and post hoc selection of the maxLCBI4mm ≥400 threshold. This study was designed a priori to substantiate the ability of NIRS to discriminate STEMI culprit from nonculprit segments and to confirm the performance of the maxLCBI4mm ≥400 threshold.
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publication status
published
subject
in
Arteriosclerosis, Thrombosis and Vascular Biology
volume
36
issue
5
pages
1010 - 1015
publisher
American Heart Association
external identifiers
  • pmid:26941016
  • scopus:84960157850
  • wos:000375230000031
ISSN
1524-4636
DOI
10.1161/ATVBAHA.115.306849
language
English
LU publication?
yes
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484926ba-dd23-4a76-8940-f93fd81d5123 (old id 8856269)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26941016?dopt=Abstract
date added to LUP
2016-03-16 14:39:27
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2017-11-12 04:07:13
@article{484926ba-dd23-4a76-8940-f93fd81d5123,
  abstract     = {In a previous exploratory analysis, intracoronary near-infrared spectroscopy (NIRS) found the majority of culprit lesions in ST-segment-elevation myocardial infarction (STEMI) to contain a maximum lipid core burden index in 4 mm (maxLCBI4mm) of >400. This initial study was limited by a small sample size, enrollment at a single center, and post hoc selection of the maxLCBI4mm ≥400 threshold. This study was designed a priori to substantiate the ability of NIRS to discriminate STEMI culprit from nonculprit segments and to confirm the performance of the maxLCBI4mm ≥400 threshold.},
  author       = {Madder, Ryan D and Puri, Rishi and Muller, James E and Harnek, Jan and Götberg, Matthias and VanOosterhout, Stacie and Chi, Margaret and Wohns, David and McNamara, Richard and Wolski, Kathy and Madden, Sean and Sidharta, Samuel and Andrews, Jordan and Nicholls, Stephen J and Erlinge, David},
  issn         = {1524-4636},
  language     = {eng},
  month        = {03},
  number       = {5},
  pages        = {1010--1015},
  publisher    = {American Heart Association},
  series       = {Arteriosclerosis, Thrombosis and Vascular Biology},
  title        = {Confirmation of the Intracoronary Near-Infrared Spectroscopy Threshold of Lipid-Rich Plaques That Underlie ST-Segment-Elevation Myocardial Infarction.},
  url          = {http://dx.doi.org/10.1161/ATVBAHA.115.306849},
  volume       = {36},
  year         = {2016},
}