Advanced

Effects of fresh frozen plasma, Ringer's acetate and albumin on plasma volume and on circulating glycocalyx components following haemorrhagic shock in rats.

Nelson, Axel LU ; Statkevicius, Svajunas LU ; Schött, Ulf LU ; Johansson, Pär I and Bentzer, Peter LU (2016) In Intensive Care Medicine Experimental 4(6).
Abstract
Early use of fresh frozen plasma (FFP) in haemorrhagic shock is associated with improved outcome. This effect may partly be due to protection of the endothelial glycocalyx and/or secondary to a superior efficacy of FFP as a plasma volume expander compared to crystalloids. The objective of the present study was to investigate if protection of the glycocalyx by FFP can be demonstrated when potential differences in plasma volume (PV) following resuscitation are accounted for.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Intensive Care Medicine Experimental
volume
4
issue
6
publisher
Springer Open
external identifiers
  • pmid:26940500
ISSN
2197-425X
DOI
10.1186/s40635-016-0080-7
language
English
LU publication?
yes
id
94e6d3f1-fce2-4bd6-8fb1-bc956aa4ea03 (old id 8856310)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26940500?dopt=Abstract
date added to LUP
2016-03-16 14:25:45
date last changed
2016-09-20 04:09:43
@article{94e6d3f1-fce2-4bd6-8fb1-bc956aa4ea03,
  abstract     = {Early use of fresh frozen plasma (FFP) in haemorrhagic shock is associated with improved outcome. This effect may partly be due to protection of the endothelial glycocalyx and/or secondary to a superior efficacy of FFP as a plasma volume expander compared to crystalloids. The objective of the present study was to investigate if protection of the glycocalyx by FFP can be demonstrated when potential differences in plasma volume (PV) following resuscitation are accounted for.},
  articleno    = {6},
  author       = {Nelson, Axel and Statkevicius, Svajunas and Schött, Ulf and Johansson, Pär I and Bentzer, Peter},
  issn         = {2197-425X},
  language     = {eng},
  number       = {6},
  publisher    = {Springer Open},
  series       = {Intensive Care Medicine Experimental},
  title        = {Effects of fresh frozen plasma, Ringer's acetate and albumin on plasma volume and on circulating glycocalyx components following haemorrhagic shock in rats.},
  url          = {http://dx.doi.org/10.1186/s40635-016-0080-7},
  volume       = {4},
  year         = {2016},
}