Global expression of AMACR transcripts predicts risk for prostate cancer - a systematic comparison of AMACR protein and mRNA expression in cancerous and noncancerous prostate.
(2016) In BMC Urology 16(1).- Abstract
- The high false negative rates for initial prostate biopsies refer a large number of the men for repeat biopsies each year. Therefore, biomarkers associated with high risk of the presence of malignancy in histologically benign biopsies could provide a tool to discriminate the patients who need repeat biopsy or intensive follow-up from those who do not. Here we examined the diagnostic applicability of alpha-methylacyl CoA racemase (AMACR) and androgen receptor (AR) mRNA expression and AMACR protein levels in benign and cancerous prostatic tissue.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/8856770
- author
- Alinezhad, Saeid ; Väänänen, Riina-Minna ; Ochoa, Natalia Tong ; Vertosick, Emily A ; Bjartell, Anders LU ; Boström, Peter J ; Taimen, Pekka and Pettersson, Kim
- organization
- publishing date
- 2016
- type
- Contribution to journal
- publication status
- published
- subject
- in
- BMC Urology
- volume
- 16
- issue
- 1
- article number
- 10
- publisher
- BioMed Central (BMC)
- external identifiers
-
- pmid:26928323
- wos:000371134400002
- scopus:84966318603
- pmid:26928323
- ISSN
- 1471-2490
- DOI
- 10.1186/s12894-016-0128-8
- language
- English
- LU publication?
- yes
- id
- 12887aa7-afc4-4f76-a047-b69c03a80b32 (old id 8856770)
- alternative location
- http://www.ncbi.nlm.nih.gov/pubmed/26928323?dopt=Abstract
- date added to LUP
- 2016-04-01 14:12:37
- date last changed
- 2022-03-21 22:50:02
@article{12887aa7-afc4-4f76-a047-b69c03a80b32, abstract = {{The high false negative rates for initial prostate biopsies refer a large number of the men for repeat biopsies each year. Therefore, biomarkers associated with high risk of the presence of malignancy in histologically benign biopsies could provide a tool to discriminate the patients who need repeat biopsy or intensive follow-up from those who do not. Here we examined the diagnostic applicability of alpha-methylacyl CoA racemase (AMACR) and androgen receptor (AR) mRNA expression and AMACR protein levels in benign and cancerous prostatic tissue.}}, author = {{Alinezhad, Saeid and Väänänen, Riina-Minna and Ochoa, Natalia Tong and Vertosick, Emily A and Bjartell, Anders and Boström, Peter J and Taimen, Pekka and Pettersson, Kim}}, issn = {{1471-2490}}, language = {{eng}}, number = {{1}}, publisher = {{BioMed Central (BMC)}}, series = {{BMC Urology}}, title = {{Global expression of AMACR transcripts predicts risk for prostate cancer - a systematic comparison of AMACR protein and mRNA expression in cancerous and noncancerous prostate.}}, url = {{http://dx.doi.org/10.1186/s12894-016-0128-8}}, doi = {{10.1186/s12894-016-0128-8}}, volume = {{16}}, year = {{2016}}, }