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Global expression of AMACR transcripts predicts risk for prostate cancer - a systematic comparison of AMACR protein and mRNA expression in cancerous and noncancerous prostate.

Alinezhad, Saeid ; Väänänen, Riina-Minna ; Ochoa, Natalia Tong ; Vertosick, Emily A ; Bjartell, Anders LU ; Boström, Peter J ; Taimen, Pekka and Pettersson, Kim (2016) In BMC Urology 16(1).
Abstract
The high false negative rates for initial prostate biopsies refer a large number of the men for repeat biopsies each year. Therefore, biomarkers associated with high risk of the presence of malignancy in histologically benign biopsies could provide a tool to discriminate the patients who need repeat biopsy or intensive follow-up from those who do not. Here we examined the diagnostic applicability of alpha-methylacyl CoA racemase (AMACR) and androgen receptor (AR) mRNA expression and AMACR protein levels in benign and cancerous prostatic tissue.
Please use this url to cite or link to this publication:
author
; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
BMC Urology
volume
16
issue
1
article number
10
publisher
BioMed Central (BMC)
external identifiers
  • pmid:26928323
  • wos:000371134400002
  • scopus:84966318603
  • pmid:26928323
ISSN
1471-2490
DOI
10.1186/s12894-016-0128-8
language
English
LU publication?
yes
id
12887aa7-afc4-4f76-a047-b69c03a80b32 (old id 8856770)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26928323?dopt=Abstract
date added to LUP
2016-04-01 14:12:37
date last changed
2022-03-21 22:50:02
@article{12887aa7-afc4-4f76-a047-b69c03a80b32,
  abstract     = {{The high false negative rates for initial prostate biopsies refer a large number of the men for repeat biopsies each year. Therefore, biomarkers associated with high risk of the presence of malignancy in histologically benign biopsies could provide a tool to discriminate the patients who need repeat biopsy or intensive follow-up from those who do not. Here we examined the diagnostic applicability of alpha-methylacyl CoA racemase (AMACR) and androgen receptor (AR) mRNA expression and AMACR protein levels in benign and cancerous prostatic tissue.}},
  author       = {{Alinezhad, Saeid and Väänänen, Riina-Minna and Ochoa, Natalia Tong and Vertosick, Emily A and Bjartell, Anders and Boström, Peter J and Taimen, Pekka and Pettersson, Kim}},
  issn         = {{1471-2490}},
  language     = {{eng}},
  number       = {{1}},
  publisher    = {{BioMed Central (BMC)}},
  series       = {{BMC Urology}},
  title        = {{Global expression of AMACR transcripts predicts risk for prostate cancer - a systematic comparison of AMACR protein and mRNA expression in cancerous and noncancerous prostate.}},
  url          = {{http://dx.doi.org/10.1186/s12894-016-0128-8}},
  doi          = {{10.1186/s12894-016-0128-8}},
  volume       = {{16}},
  year         = {{2016}},
}