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Global expression of AMACR transcripts predicts risk for prostate cancer - a systematic comparison of AMACR protein and mRNA expression in cancerous and noncancerous prostate.

Alinezhad, Saeid; Väänänen, Riina-Minna; Ochoa, Natalia Tong; Vertosick, Emily A; Bjartell, Anders LU ; Boström, Peter J; Taimen, Pekka and Pettersson, Kim (2016) In BMC Urology 16(1).
Abstract
The high false negative rates for initial prostate biopsies refer a large number of the men for repeat biopsies each year. Therefore, biomarkers associated with high risk of the presence of malignancy in histologically benign biopsies could provide a tool to discriminate the patients who need repeat biopsy or intensive follow-up from those who do not. Here we examined the diagnostic applicability of alpha-methylacyl CoA racemase (AMACR) and androgen receptor (AR) mRNA expression and AMACR protein levels in benign and cancerous prostatic tissue.
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
BMC Urology
volume
16
issue
1
publisher
BioMed Central
external identifiers
  • pmid:26928323
  • wos:000371134400002
  • scopus:84966318603
ISSN
1471-2490
DOI
10.1186/s12894-016-0128-8
language
English
LU publication?
yes
id
12887aa7-afc4-4f76-a047-b69c03a80b32 (old id 8856770)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/26928323?dopt=Abstract
date added to LUP
2016-03-15 10:02:00
date last changed
2017-07-09 04:04:14
@article{12887aa7-afc4-4f76-a047-b69c03a80b32,
  abstract     = {The high false negative rates for initial prostate biopsies refer a large number of the men for repeat biopsies each year. Therefore, biomarkers associated with high risk of the presence of malignancy in histologically benign biopsies could provide a tool to discriminate the patients who need repeat biopsy or intensive follow-up from those who do not. Here we examined the diagnostic applicability of alpha-methylacyl CoA racemase (AMACR) and androgen receptor (AR) mRNA expression and AMACR protein levels in benign and cancerous prostatic tissue.},
  articleno    = {10},
  author       = {Alinezhad, Saeid and Väänänen, Riina-Minna and Ochoa, Natalia Tong and Vertosick, Emily A and Bjartell, Anders and Boström, Peter J and Taimen, Pekka and Pettersson, Kim},
  issn         = {1471-2490},
  language     = {eng},
  number       = {1},
  publisher    = {BioMed Central},
  series       = {BMC Urology},
  title        = {Global expression of AMACR transcripts predicts risk for prostate cancer - a systematic comparison of AMACR protein and mRNA expression in cancerous and noncancerous prostate.},
  url          = {http://dx.doi.org/10.1186/s12894-016-0128-8},
  volume       = {16},
  year         = {2016},
}