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On the appearance of bile in clinical MR cholangiopancreatography

Hakansson, K; Christoffersson, JO; Leander, Peter LU ; Ekberg, Olle LU and Hakansson, HO (2002) In Acta Radiologica 43(4). p.401-410
Abstract
Purpose: To study the appearance of bile in clinical MR cholangiopancreatography (MRCP) with special reference to its chemical and physical properties. Material and Methods: Gallbladder bile was collected during surgery from 38 patients and studied with respect to chemical constituents. The relaxation rates 1/T1 and 1/T2 of bile were also determined in vitro . In 16 of these 38 patients, abdominal imaging was performed using MRCP as well as T1-weighted GE sequences. Results: For 9 of the 13 chemical parameters studied, a positive significant correlation with 1/T1 as well as 1/T2 was found. The median relaxation rates 1/T1 and 1/T2 were 0.76 and 1.48 s(-1) , respectively. The corresponding ranges were 0.38-3.13 s(-1) and 0.70-5.75 s(-1) ,... (More)
Purpose: To study the appearance of bile in clinical MR cholangiopancreatography (MRCP) with special reference to its chemical and physical properties. Material and Methods: Gallbladder bile was collected during surgery from 38 patients and studied with respect to chemical constituents. The relaxation rates 1/T1 and 1/T2 of bile were also determined in vitro . In 16 of these 38 patients, abdominal imaging was performed using MRCP as well as T1-weighted GE sequences. Results: For 9 of the 13 chemical parameters studied, a positive significant correlation with 1/T1 as well as 1/T2 was found. The median relaxation rates 1/T1 and 1/T2 were 0.76 and 1.48 s(-1) , respectively. The corresponding ranges were 0.38-3.13 s(-1) and 0.70-5.75 s(-1) , respectively. On the MRCP images a few patients showed gallbladder of poor visibility due to low signal-to-noise ratio. This coincided with a high relaxation rate 1/T2 of bile. On the T1-weighted GE sequences a few patients showed hyperintense gallbladder relative to liver, coinciding with high relaxation rates 1/T1 of bile. Conclusion: Bile was found to show a large interindividual variation with respect to relaxation rates 1/T1 and 1/T2. The relaxation rates increased with increasing amounts of substances in the bile. For some patients (11%) MRCP imaging is unsuccessful due to high relaxation rate of bile. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
technology, MR cholangiopancretography, bile, gallbladder
in
Acta Radiologica
volume
43
issue
4
pages
401 - 410
publisher
John Wiley & Sons
external identifiers
  • wos:000177948700011
  • pmid:12225483
  • scopus:0036628579
ISSN
1600-0455
language
English
LU publication?
yes
id
500c5a23-137a-4b2e-a048-108cb34dcdb3 (old id 892679)
date added to LUP
2008-01-22 17:07:27
date last changed
2017-01-01 07:16:25
@article{500c5a23-137a-4b2e-a048-108cb34dcdb3,
  abstract     = {Purpose: To study the appearance of bile in clinical MR cholangiopancreatography (MRCP) with special reference to its chemical and physical properties. Material and Methods: Gallbladder bile was collected during surgery from 38 patients and studied with respect to chemical constituents. The relaxation rates 1/T1 and 1/T2 of bile were also determined in vitro . In 16 of these 38 patients, abdominal imaging was performed using MRCP as well as T1-weighted GE sequences. Results: For 9 of the 13 chemical parameters studied, a positive significant correlation with 1/T1 as well as 1/T2 was found. The median relaxation rates 1/T1 and 1/T2 were 0.76 and 1.48 s(-1) , respectively. The corresponding ranges were 0.38-3.13 s(-1) and 0.70-5.75 s(-1) , respectively. On the MRCP images a few patients showed gallbladder of poor visibility due to low signal-to-noise ratio. This coincided with a high relaxation rate 1/T2 of bile. On the T1-weighted GE sequences a few patients showed hyperintense gallbladder relative to liver, coinciding with high relaxation rates 1/T1 of bile. Conclusion: Bile was found to show a large interindividual variation with respect to relaxation rates 1/T1 and 1/T2. The relaxation rates increased with increasing amounts of substances in the bile. For some patients (11%) MRCP imaging is unsuccessful due to high relaxation rate of bile.},
  author       = {Hakansson, K and Christoffersson, JO and Leander, Peter and Ekberg, Olle and Hakansson, HO},
  issn         = {1600-0455},
  keyword      = {technology,MR cholangiopancretography,bile,gallbladder},
  language     = {eng},
  number       = {4},
  pages        = {401--410},
  publisher    = {John Wiley & Sons},
  series       = {Acta Radiologica},
  title        = {On the appearance of bile in clinical MR cholangiopancreatography},
  volume       = {43},
  year         = {2002},
}