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Multicenter study for the evaluation of a dedicated biopsy device for MR-guided vacuum biopsy of the breast

Perlet, C; Heinig, A; Prat, X; Casselman, J; Bååth, Lars LU ; Sittek, H; Stets, C; Lamarque, J; Anderson, I and Schneider, P, et al. (2002) In European Radiology 12(6). p.1463-1470
Abstract
The purpose of this multicenter study was to determine the accuracy and clinical value of a dedicated breast biopsy system which allows for MR-guided vacuum biopsy (VB) of contrast-enhancing lesions. In five European centers, MR-guided 11-gauge VB was performed on 341 lesions. In 7 cases VB was unsuccessful. This was immediately realized on postinterventional images or direct follow-up combined with histopathology-imaging correlation; thus, a false-negative diagnosis was avoided. Histology of 334 successful biopsies yielded 84 (25%) malignancies, 17 (5%) atypical ductal hyperplasias, and 233 (70%) benign entities. Verification of malignant or borderline lesions included re-excision of the biopsy cavity. Benign histologic biopsy results... (More)
The purpose of this multicenter study was to determine the accuracy and clinical value of a dedicated breast biopsy system which allows for MR-guided vacuum biopsy (VB) of contrast-enhancing lesions. In five European centers, MR-guided 11-gauge VB was performed on 341 lesions. In 7 cases VB was unsuccessful. This was immediately realized on postinterventional images or direct follow-up combined with histopathology-imaging correlation; thus, a false-negative diagnosis was avoided. Histology of 334 successful biopsies yielded 84 (25%) malignancies, 17 (5%) atypical ductal hyperplasias, and 233 (70%) benign entities. Verification of malignant or borderline lesions included re-excision of the biopsy cavity. Benign histologic biopsy results were verified by retrospective correlation with the pre- and postinterventional MRI and by subsequent follow-up. Our results indicate that MR-guided VB, in combination with the dedicated biopsy coil, offers the possibility to accurately diagnose even very small lesions that can only be visualized or localized by MRI. (Less)
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publication status
published
subject
keywords
intervention, biopsy, breast, MR imaging
in
European Radiology
volume
12
issue
6
pages
1463 - 1470
publisher
Springer
external identifiers
  • wos:000176197400028
  • pmid:12042955
  • scopus:0036598381
ISSN
0938-7994
DOI
10.1007/s00330-002-1376-4
language
English
LU publication?
yes
id
9effb180-9b50-406a-b09c-524ac780e5d8 (old id 893119)
date added to LUP
2008-01-18 15:24:19
date last changed
2017-12-10 03:52:11
@article{9effb180-9b50-406a-b09c-524ac780e5d8,
  abstract     = {The purpose of this multicenter study was to determine the accuracy and clinical value of a dedicated breast biopsy system which allows for MR-guided vacuum biopsy (VB) of contrast-enhancing lesions. In five European centers, MR-guided 11-gauge VB was performed on 341 lesions. In 7 cases VB was unsuccessful. This was immediately realized on postinterventional images or direct follow-up combined with histopathology-imaging correlation; thus, a false-negative diagnosis was avoided. Histology of 334 successful biopsies yielded 84 (25%) malignancies, 17 (5%) atypical ductal hyperplasias, and 233 (70%) benign entities. Verification of malignant or borderline lesions included re-excision of the biopsy cavity. Benign histologic biopsy results were verified by retrospective correlation with the pre- and postinterventional MRI and by subsequent follow-up. Our results indicate that MR-guided VB, in combination with the dedicated biopsy coil, offers the possibility to accurately diagnose even very small lesions that can only be visualized or localized by MRI.},
  author       = {Perlet, C and Heinig, A and Prat, X and Casselman, J and Bååth, Lars and Sittek, H and Stets, C and Lamarque, J and Anderson, I and Schneider, P and Taourel, P and Reiser, M and Heywang-Kobrunner, SH},
  issn         = {0938-7994},
  keyword      = {intervention,biopsy,breast,MR imaging},
  language     = {eng},
  number       = {6},
  pages        = {1463--1470},
  publisher    = {Springer},
  series       = {European Radiology},
  title        = {Multicenter study for the evaluation of a dedicated biopsy device for MR-guided vacuum biopsy of the breast},
  url          = {http://dx.doi.org/10.1007/s00330-002-1376-4},
  volume       = {12},
  year         = {2002},
}