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Current methods for absorbed dose planning for radioiodine treatment of hyperthyroidism in Sweden

Jonsson, H and Mattsson, Sören LU (2004) In Physica Medica 20(3). p.99-103
Abstract
Radioiodine therapy is a common form for treatment of hyperthyroidism. This treatment has been performed for half a century, with the annual number of I-131-iodide therapies for hyperthyroidism in Sweden being around 3000 since the 1970s. Methods used to calculate the administered activity to the individual patient differ widely, and a survey was made to get information about the different protocols currently used in 23 hospitals in Sweden, which administer radioiodide for therapy of hyperthyroidism. Eighteen hospitals calculate the activity to be administered for a prescribed absorbed dose to the thyroid. The calculations of the activity to administer consider individual parameters such as the active volume of the thyroid and its uptake... (More)
Radioiodine therapy is a common form for treatment of hyperthyroidism. This treatment has been performed for half a century, with the annual number of I-131-iodide therapies for hyperthyroidism in Sweden being around 3000 since the 1970s. Methods used to calculate the administered activity to the individual patient differ widely, and a survey was made to get information about the different protocols currently used in 23 hospitals in Sweden, which administer radioiodide for therapy of hyperthyroidism. Eighteen hospitals calculate the activity to be administered for a prescribed absorbed dose to the thyroid. The calculations of the activity to administer consider individual parameters such as the active volume of the thyroid and its uptake of I-131-iodide, but only 9 of the 18 hospitals consider the individual biological half time of I-131 in the thyroid. Five hospitals do not consider any individual biokinetic parameter or volume and prescribe just the activity to be administered. In total, 17 different protocols are used, and the investigation clearly illustrates the need to converge and optimize the radioiodine therapy in Sweden. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
absorbed dose, hyperthyroidism, radioiodine, therapy
in
Physica Medica
volume
20
issue
3
pages
99 - 103
publisher
ISTITUTI EDITORIALI E POLGRAFICI INTERNAZIONALI
external identifiers
  • wos:000227232800002
  • scopus:13444265964
ISSN
1120-1797
language
English
LU publication?
yes
id
aa9033e6-8a01-4fbb-be01-c11fbd17c72b (old id 897374)
date added to LUP
2008-01-15 11:22:34
date last changed
2017-01-01 05:09:26
@article{aa9033e6-8a01-4fbb-be01-c11fbd17c72b,
  abstract     = {Radioiodine therapy is a common form for treatment of hyperthyroidism. This treatment has been performed for half a century, with the annual number of I-131-iodide therapies for hyperthyroidism in Sweden being around 3000 since the 1970s. Methods used to calculate the administered activity to the individual patient differ widely, and a survey was made to get information about the different protocols currently used in 23 hospitals in Sweden, which administer radioiodide for therapy of hyperthyroidism. Eighteen hospitals calculate the activity to be administered for a prescribed absorbed dose to the thyroid. The calculations of the activity to administer consider individual parameters such as the active volume of the thyroid and its uptake of I-131-iodide, but only 9 of the 18 hospitals consider the individual biological half time of I-131 in the thyroid. Five hospitals do not consider any individual biokinetic parameter or volume and prescribe just the activity to be administered. In total, 17 different protocols are used, and the investigation clearly illustrates the need to converge and optimize the radioiodine therapy in Sweden.},
  author       = {Jonsson, H and Mattsson, Sören},
  issn         = {1120-1797},
  keyword      = {absorbed dose,hyperthyroidism,radioiodine,therapy},
  language     = {eng},
  number       = {3},
  pages        = {99--103},
  publisher    = {ISTITUTI EDITORIALI E POLGRAFICI INTERNAZIONALI},
  series       = {Physica Medica},
  title        = {Current methods for absorbed dose planning for radioiodine treatment of hyperthyroidism in Sweden},
  volume       = {20},
  year         = {2004},
}