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Requirements for DXA for the management of osteoporosis in Europe

Kanis, JA and Johnell, Olof LU (2005) In Osteoporosis International 16(3). p.229-238
Abstract
The availability of dual energy X-ray absorptiometry (DXA) varies markedly in different countries. There is, however, little information to indicate the optimal requirements for this technology. The principal aim of this study was to estimate the requirements for DXA in Europe for the assessment and treatment of osteoporosis. Three assessment scenarios were chosen. The first envisaged screening of all women with DXA at the age of 65 years. A second scenario comprised a screening programme based on the identification of clinical risk factors with the selective addition of BMD tests in those close to an intervention threshold. The third scenario envisaged a case finding strategy where women aged 65 years were identified on the basis of risk... (More)
The availability of dual energy X-ray absorptiometry (DXA) varies markedly in different countries. There is, however, little information to indicate the optimal requirements for this technology. The principal aim of this study was to estimate the requirements for DXA in Europe for the assessment and treatment of osteoporosis. Three assessment scenarios were chosen. The first envisaged screening of all women with DXA at the age of 65 years. A second scenario comprised a screening programme based on the identification of clinical risk factors with the selective addition of BMD tests in those close to an intervention threshold. The third scenario envisaged a case finding strategy where women aged 65 years were identified on the basis of risk factors and referred for DXA. Requirements for women aged more than 65 years were amortised over a 10-year period. A secondary aim was to estimate the number and cost of osteoporotic fractures in Europe. The requirements for DXA in assessment ranged from 4.21 to 11.21 units/million of the population. The most efficient assessment scenario was the use of clinical risk factors with the selective use of BMD. With this scenario, an additional 6.39 units/million would be required to monitor treatment giving a total requirement of 10.6 units/million. In 2000, the number of osteoporotic fractures was estimated at 3.79 million, of which 0.89 million were hip fractures ( 179,000 hip fractures in men and 711,000 in women). The total direct costs were estimated at 31.7 billion (pound21.165 billion), which were expected to increase to E76.7 billion (pound51.1 billion) in 2050 based on the expected changes in the demography of Europe. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Europe, dual energy X-ray absorptiometry, fracture probability, hip, fracture, osteoporotic fracture, risk assessment, screening
in
Osteoporosis International
volume
16
issue
3
pages
229 - 238
publisher
Springer
external identifiers
  • pmid:15618996
  • wos:000227237700001
  • scopus:15044344862
ISSN
1433-2965
DOI
10.1007/s00198-004-1811-2
language
English
LU publication?
yes
id
db832d85-eb31-45b6-a557-78fd752031ff (old id 897377)
date added to LUP
2008-01-16 12:25:25
date last changed
2017-11-05 04:30:17
@article{db832d85-eb31-45b6-a557-78fd752031ff,
  abstract     = {The availability of dual energy X-ray absorptiometry (DXA) varies markedly in different countries. There is, however, little information to indicate the optimal requirements for this technology. The principal aim of this study was to estimate the requirements for DXA in Europe for the assessment and treatment of osteoporosis. Three assessment scenarios were chosen. The first envisaged screening of all women with DXA at the age of 65 years. A second scenario comprised a screening programme based on the identification of clinical risk factors with the selective addition of BMD tests in those close to an intervention threshold. The third scenario envisaged a case finding strategy where women aged 65 years were identified on the basis of risk factors and referred for DXA. Requirements for women aged more than 65 years were amortised over a 10-year period. A secondary aim was to estimate the number and cost of osteoporotic fractures in Europe. The requirements for DXA in assessment ranged from 4.21 to 11.21 units/million of the population. The most efficient assessment scenario was the use of clinical risk factors with the selective use of BMD. With this scenario, an additional 6.39 units/million would be required to monitor treatment giving a total requirement of 10.6 units/million. In 2000, the number of osteoporotic fractures was estimated at 3.79 million, of which 0.89 million were hip fractures ( 179,000 hip fractures in men and 711,000 in women). The total direct costs were estimated at 31.7 billion (pound21.165 billion), which were expected to increase to E76.7 billion (pound51.1 billion) in 2050 based on the expected changes in the demography of Europe.},
  author       = {Kanis, JA and Johnell, Olof},
  issn         = {1433-2965},
  keyword      = {Europe,dual energy X-ray absorptiometry,fracture probability,hip,fracture,osteoporotic fracture,risk assessment,screening},
  language     = {eng},
  number       = {3},
  pages        = {229--238},
  publisher    = {Springer},
  series       = {Osteoporosis International},
  title        = {Requirements for DXA for the management of osteoporosis in Europe},
  url          = {http://dx.doi.org/10.1007/s00198-004-1811-2},
  volume       = {16},
  year         = {2005},
}