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Monitoring of atherosclerosis

Zhdanov, VS and Sternby, Nils LU (2004) In International Journal of Cardiology 95(1). p.39-42
Abstract
Population-based epidemiological studies of atherosclerosis using autopsy material is now impossible to perform in most countries due to declining autopsy rates. Based on epidemiological studies of atherosclerosis using autopsy material in five European cities which were carried out with an interval of 25 years in the 1960s and 1980s, respectively, we have shown that atherosclerosis in young so-called practically healthy people, 20-39 years of age, who died from accidental causes, closely reflects the level of atherosclerosis in the population as a whole. These people can thus be used for monitoring the development of atherosclerosis in a population since they are normally a subject to a medico-legal autopsy; therefore, material for such... (More)
Population-based epidemiological studies of atherosclerosis using autopsy material is now impossible to perform in most countries due to declining autopsy rates. Based on epidemiological studies of atherosclerosis using autopsy material in five European cities which were carried out with an interval of 25 years in the 1960s and 1980s, respectively, we have shown that atherosclerosis in young so-called practically healthy people, 20-39 years of age, who died from accidental causes, closely reflects the level of atherosclerosis in the population as a whole. These people can thus be used for monitoring the development of atherosclerosis in a population since they are normally a subject to a medico-legal autopsy; therefore, material for such studies can be obtained. Furthermore, histomorphological studies of specimens that are taken from practically healthy people at standard places of coronary arteries and aortas also reflect this general level of atherosclerosis. These studies also provide information on the atherosclerotic process and its relation to various risk factors. (C) 2003 Elsevier Ireland Ltd. All rights reserved. (Less)
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author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
monitoring, autopsy, atherosclerosis, epidemiology
in
International Journal of Cardiology
volume
95
issue
1
pages
39 - 42
publisher
Elsevier
external identifiers
  • pmid:15159036
  • wos:000222205800007
  • scopus:2442666255
ISSN
0167-5273
DOI
10.1016/j.ijcard.2003.03.018
language
English
LU publication?
yes
id
6dd0ca79-f8dd-48f7-ba60-fae6f932ced9 (old id 898878)
date added to LUP
2016-04-01 11:47:13
date last changed
2022-01-26 18:13:29
@article{6dd0ca79-f8dd-48f7-ba60-fae6f932ced9,
  abstract     = {{Population-based epidemiological studies of atherosclerosis using autopsy material is now impossible to perform in most countries due to declining autopsy rates. Based on epidemiological studies of atherosclerosis using autopsy material in five European cities which were carried out with an interval of 25 years in the 1960s and 1980s, respectively, we have shown that atherosclerosis in young so-called practically healthy people, 20-39 years of age, who died from accidental causes, closely reflects the level of atherosclerosis in the population as a whole. These people can thus be used for monitoring the development of atherosclerosis in a population since they are normally a subject to a medico-legal autopsy; therefore, material for such studies can be obtained. Furthermore, histomorphological studies of specimens that are taken from practically healthy people at standard places of coronary arteries and aortas also reflect this general level of atherosclerosis. These studies also provide information on the atherosclerotic process and its relation to various risk factors. (C) 2003 Elsevier Ireland Ltd. All rights reserved.}},
  author       = {{Zhdanov, VS and Sternby, Nils}},
  issn         = {{0167-5273}},
  keywords     = {{monitoring; autopsy; atherosclerosis; epidemiology}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{39--42}},
  publisher    = {{Elsevier}},
  series       = {{International Journal of Cardiology}},
  title        = {{Monitoring of atherosclerosis}},
  url          = {{http://dx.doi.org/10.1016/j.ijcard.2003.03.018}},
  doi          = {{10.1016/j.ijcard.2003.03.018}},
  volume       = {{95}},
  year         = {{2004}},
}