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Excess mortality after hospitalisation for vertebral fracture

Kanis, JA; Oden, A; Johnell, Olof LU ; De Laet, C and Jonsson, B (2004) In Osteoporosis International 15(2). p.108-112
Abstract
An excess mortality is well described after vertebral fracture. Deaths are in part related to co-morbidity, but could also be due to the fracture event itself, either directly or indirectly. The aim of this study was to examine the quantum and pattern of mortality following vertebral fracture. We identified 16,051 men and women aged 50 years or more with a vertebral fracture that required hospitalization in 28.8 million person years from the patient register of Sweden. Mortality after vertebral fracture was examined using Poisson models applied to fracture patients and compared to that of the general population. At all ages, the risk of death was markedly increased immediately after the event. After a short period of declining risk, the... (More)
An excess mortality is well described after vertebral fracture. Deaths are in part related to co-morbidity, but could also be due to the fracture event itself, either directly or indirectly. The aim of this study was to examine the quantum and pattern of mortality following vertebral fracture. We identified 16,051 men and women aged 50 years or more with a vertebral fracture that required hospitalization in 28.8 million person years from the patient register of Sweden. Mortality after vertebral fracture was examined using Poisson models applied to fracture patients and compared to that of the general population. At all ages, the risk of death was markedly increased immediately after the event. After a short period of declining risk, the risk increased with age at a rate that was higher than that of the general population and comparable to that 1 year after hip fracture. The latter function was assumed to be due to deaths related to co-morbidity and the residuum assumed to be due to the vertebral fracture. Causally related deaths comprised 28% of all deaths associated with vertebral fracture (depending on age). We conclude that a minority of deaths following hospitalization for vertebral fracture are attributable to the fracture itself under the assumptions we used. (Less)
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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
vertebral fracture, mortality
in
Osteoporosis International
volume
15
issue
2
pages
108 - 112
publisher
Springer
external identifiers
  • pmid:14598026
  • wos:000188244200004
  • scopus:1342289957
ISSN
1433-2965
DOI
10.1007/s00198-003-1516-y
language
English
LU publication?
yes
id
a8c20eef-6a68-4c7c-a53f-a2b19ada0a00 (old id 899494)
date added to LUP
2008-01-15 12:28:46
date last changed
2017-11-26 03:49:07
@article{a8c20eef-6a68-4c7c-a53f-a2b19ada0a00,
  abstract     = {An excess mortality is well described after vertebral fracture. Deaths are in part related to co-morbidity, but could also be due to the fracture event itself, either directly or indirectly. The aim of this study was to examine the quantum and pattern of mortality following vertebral fracture. We identified 16,051 men and women aged 50 years or more with a vertebral fracture that required hospitalization in 28.8 million person years from the patient register of Sweden. Mortality after vertebral fracture was examined using Poisson models applied to fracture patients and compared to that of the general population. At all ages, the risk of death was markedly increased immediately after the event. After a short period of declining risk, the risk increased with age at a rate that was higher than that of the general population and comparable to that 1 year after hip fracture. The latter function was assumed to be due to deaths related to co-morbidity and the residuum assumed to be due to the vertebral fracture. Causally related deaths comprised 28% of all deaths associated with vertebral fracture (depending on age). We conclude that a minority of deaths following hospitalization for vertebral fracture are attributable to the fracture itself under the assumptions we used.},
  author       = {Kanis, JA and Oden, A and Johnell, Olof and De Laet, C and Jonsson, B},
  issn         = {1433-2965},
  keyword      = {vertebral fracture,mortality},
  language     = {eng},
  number       = {2},
  pages        = {108--112},
  publisher    = {Springer},
  series       = {Osteoporosis International},
  title        = {Excess mortality after hospitalisation for vertebral fracture},
  url          = {http://dx.doi.org/10.1007/s00198-003-1516-y},
  volume       = {15},
  year         = {2004},
}