Molekylär patologi – nyckeln till målinriktad cancerbehandling
(2021) In Lakartidningen 118.- Abstract
Rapidly expanding knowledge of the molecular landscape of cancers has resulted in the implementation of an increasing number of specific therapies targeted at tumors with specific molecular aberrations. In response to this development, new tools for predictive testing for molecular targets need to be implemented in routine health care. To achieve robust future molecular diagnostic pathology, and equal opportunity for patients to qualify for targeted therapy, the national working group for Solid Tumors in the initiative Genomic Medicine Sweden (GMS) aims to implement regional and national platforms for comprehensive genomic tumor profiling and linked analysis pipelines. Novel IT-infrastrucutures and recruitment of bioinformaticians and... (More)
Rapidly expanding knowledge of the molecular landscape of cancers has resulted in the implementation of an increasing number of specific therapies targeted at tumors with specific molecular aberrations. In response to this development, new tools for predictive testing for molecular targets need to be implemented in routine health care. To achieve robust future molecular diagnostic pathology, and equal opportunity for patients to qualify for targeted therapy, the national working group for Solid Tumors in the initiative Genomic Medicine Sweden (GMS) aims to implement regional and national platforms for comprehensive genomic tumor profiling and linked analysis pipelines. Novel IT-infrastrucutures and recruitment of bioinformaticians and molecular biologists to hospital labotatories are paramount. The infrastructure will allow wider inclusion into clinical trials and supplement the national cancer registries with molecular »real world data« for research and evaluation of implemented cancer therapies and diagnostic procedures.
(Less)- Abstract (Swedish)
- Molekylär kunskap om tumörutveckling leder till allt fler målinriktade cancerbehandlingar.
Heltäckande molekylär tumörkarakterisering ger möjlighet att undersöka samtliga behandlingsalternativ med en analys.
Arbetsutskottet för solida tumörer inom Genomic Medicine Sweden samarbetar för att etablera regional och nationell infrastruktur för storskalig tumörsekvensering och kopplad dataanalys i sjukvården.
Utvecklingen ställer nya krav på vården, bland annat när det gäller kunskapsöverföring och rekrytering av nya kompetenser.
Långsiktiga mål är specifik cancerterapi för varje enskild patient, bättre möjlighet att bedriva kliniska behandlingsstudier och koppling av molekylära tumördata till landets... (More) - Molekylär kunskap om tumörutveckling leder till allt fler målinriktade cancerbehandlingar.
Heltäckande molekylär tumörkarakterisering ger möjlighet att undersöka samtliga behandlingsalternativ med en analys.
Arbetsutskottet för solida tumörer inom Genomic Medicine Sweden samarbetar för att etablera regional och nationell infrastruktur för storskalig tumörsekvensering och kopplad dataanalys i sjukvården.
Utvecklingen ställer nya krav på vården, bland annat när det gäller kunskapsöverföring och rekrytering av nya kompetenser.
Långsiktiga mål är specifik cancerterapi för varje enskild patient, bättre möjlighet att bedriva kliniska behandlingsstudier och koppling av molekylära tumördata till landets cancerregister. (Less)
- author
- Edsjö, Anders LU ; Palmqvist, Richard ; Haglund, Felix ; Helenius, Gisela ; Lindqvist, Oscar ; Fagman, Henrik and Botling, Johan
- organization
- alternative title
- Molecular pathology - the key to precision oncology
- publishing date
- 2021-05-10
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Lakartidningen
- volume
- 118
- publisher
- Swedish Medical Association
- external identifiers
-
- scopus:85105768082
- pmid:33973224
- ISSN
- 0023-7205
- language
- Swedish
- LU publication?
- yes
- id
- 89ff952d-b625-49c1-81df-51bda18ca246
- date added to LUP
- 2022-01-03 12:13:47
- date last changed
- 2024-06-01 22:58:04
@article{89ff952d-b625-49c1-81df-51bda18ca246,
abstract = {{<p>Rapidly expanding knowledge of the molecular landscape of cancers has resulted in the implementation of an increasing number of specific therapies targeted at tumors with specific molecular aberrations. In response to this development, new tools for predictive testing for molecular targets need to be implemented in routine health care. To achieve robust future molecular diagnostic pathology, and equal opportunity for patients to qualify for targeted therapy, the national working group for Solid Tumors in the initiative Genomic Medicine Sweden (GMS) aims to implement regional and national platforms for comprehensive genomic tumor profiling and linked analysis pipelines. Novel IT-infrastrucutures and recruitment of bioinformaticians and molecular biologists to hospital labotatories are paramount. The infrastructure will allow wider inclusion into clinical trials and supplement the national cancer registries with molecular »real world data« for research and evaluation of implemented cancer therapies and diagnostic procedures.</p>}},
author = {{Edsjö, Anders and Palmqvist, Richard and Haglund, Felix and Helenius, Gisela and Lindqvist, Oscar and Fagman, Henrik and Botling, Johan}},
issn = {{0023-7205}},
language = {{swe}},
month = {{05}},
publisher = {{Swedish Medical Association}},
series = {{Lakartidningen}},
title = {{Molekylär patologi – nyckeln till målinriktad cancerbehandling}},
volume = {{118}},
year = {{2021}},
}