Neurotransmitter candidates in the vomeronasal organ of the rat.
(2007) In Acta Oto-Laryngologica 127(9). p.952-956- Abstract
- Conclusion: The rich supply of nerve fibres containing neurotransmitters, particularly those containing SP and CGRP, is suggested to be a prerequisite for the recognition of chemical irritants as part of a chemical sense. Objective: The present study was designed to examine the distribution of different neurotransmitter candidates in the vomeronasal organ (VNO) of rats. Materials and methods: The distribution of neurotransmitter candidates was studied in the vomeronasal organ of the rat using immunocytochemistry. Results: The neuronal marker protein gene product 9.5 revealed a very rich supply of nerve fibres within and beneath the sensory epithelium, around blood vessels and glands. A moderate supply of nerve fibres containing tyrosine... (More)
- Conclusion: The rich supply of nerve fibres containing neurotransmitters, particularly those containing SP and CGRP, is suggested to be a prerequisite for the recognition of chemical irritants as part of a chemical sense. Objective: The present study was designed to examine the distribution of different neurotransmitter candidates in the vomeronasal organ (VNO) of rats. Materials and methods: The distribution of neurotransmitter candidates was studied in the vomeronasal organ of the rat using immunocytochemistry. Results: The neuronal marker protein gene product 9.5 revealed a very rich supply of nerve fibres within and beneath the sensory epithelium, around blood vessels and glands. A moderate supply of nerve fibres containing tyrosine hydroxylase and neuropeptide Y was mostly seen close to blood vessels. Numerous nerve fibres containing nitric oxide synthase and vasoactive intestinal peptide were seen around blood vessels and in the subepithelial layer, with occasional fibres within the epithelium. Only few fibres located in the subepithelial layer contained pituitary adenylate cyclase activating peptide. Nerve fibres containing substance P and in particular calcitonin gene-related peptide were abundant in and beneath the epithelium and scattered in the submucosal layers around blood vessels. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/606697
- author
- Uddman, Rolf LU ; Malm, Lars LU and Cardell, Lars-Olaf LU
- organization
- publishing date
- 2007
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- immunocytochemistry, rat, neuropeptides, vomeronasal organ, accessory olfactory system
- in
- Acta Oto-Laryngologica
- volume
- 127
- issue
- 9
- pages
- 952 - 956
- publisher
- Taylor & Francis
- external identifiers
-
- wos:000248942100010
- scopus:34548329732
- pmid:17712675
- ISSN
- 1651-2251
- DOI
- 10.1080/00016480601110220
- language
- English
- LU publication?
- yes
- id
- 8ab5bc95-d618-45ad-9eae-5f6ba9726561 (old id 606697)
- alternative location
- http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=17712675&dopt=Abstract
- date added to LUP
- 2016-04-01 15:50:51
- date last changed
- 2022-01-28 07:33:13
@article{8ab5bc95-d618-45ad-9eae-5f6ba9726561,
abstract = {{Conclusion: The rich supply of nerve fibres containing neurotransmitters, particularly those containing SP and CGRP, is suggested to be a prerequisite for the recognition of chemical irritants as part of a chemical sense. Objective: The present study was designed to examine the distribution of different neurotransmitter candidates in the vomeronasal organ (VNO) of rats. Materials and methods: The distribution of neurotransmitter candidates was studied in the vomeronasal organ of the rat using immunocytochemistry. Results: The neuronal marker protein gene product 9.5 revealed a very rich supply of nerve fibres within and beneath the sensory epithelium, around blood vessels and glands. A moderate supply of nerve fibres containing tyrosine hydroxylase and neuropeptide Y was mostly seen close to blood vessels. Numerous nerve fibres containing nitric oxide synthase and vasoactive intestinal peptide were seen around blood vessels and in the subepithelial layer, with occasional fibres within the epithelium. Only few fibres located in the subepithelial layer contained pituitary adenylate cyclase activating peptide. Nerve fibres containing substance P and in particular calcitonin gene-related peptide were abundant in and beneath the epithelium and scattered in the submucosal layers around blood vessels.}},
author = {{Uddman, Rolf and Malm, Lars and Cardell, Lars-Olaf}},
issn = {{1651-2251}},
keywords = {{immunocytochemistry; rat; neuropeptides; vomeronasal organ; accessory olfactory system}},
language = {{eng}},
number = {{9}},
pages = {{952--956}},
publisher = {{Taylor & Francis}},
series = {{Acta Oto-Laryngologica}},
title = {{Neurotransmitter candidates in the vomeronasal organ of the rat.}},
url = {{http://dx.doi.org/10.1080/00016480601110220}},
doi = {{10.1080/00016480601110220}},
volume = {{127}},
year = {{2007}},
}