Thrombus Embolization Into IVC Filters During Catheter-Directed Thrombolysis for Proximal Deep Venous Thrombosis
(2008) In Journal of Endovascular Therapy 15(5). p.605-613- Abstract
- Purpose: To assess the frequency of embolization into retrievable inferior vena cava (IVC) filters during catheter-directed thrombolysis (CDT) and stent placement for acute iliocaval deep venous thrombosis (DVT). Methods: Serial phlebograms from 40 patients (28 women; median age 32 years) consecutively treated with CDT for DVT during a 12-year period were retrospectively evaluated for visible emboli in the IVC filter. Clinical and procedural data extracted from a prospectively maintained database were evaluated to identify predictors for embolization into the filter. Results: Visible emboli were found in 18 (45%) patients. Visible embolization to the IVC filter was less frequent in patients with a hypercoagulable disorder (n=29, 31%) than... (More)
- Purpose: To assess the frequency of embolization into retrievable inferior vena cava (IVC) filters during catheter-directed thrombolysis (CDT) and stent placement for acute iliocaval deep venous thrombosis (DVT). Methods: Serial phlebograms from 40 patients (28 women; median age 32 years) consecutively treated with CDT for DVT during a 12-year period were retrospectively evaluated for visible emboli in the IVC filter. Clinical and procedural data extracted from a prospectively maintained database were evaluated to identify predictors for embolization into the filter. Results: Visible emboli were found in 18 (45%) patients. Visible embolization to the IVC filter was less frequent in patients with a hypercoagulable disorder (n=29, 31%) than in patients without a hypercoagulable disorder (n=11, 69%; OR 0.1, 95% Cl 0.02 to 0.56, p=0.006). No patient developed clinical symptomatic pulmonary embolism or a complication related to the placement or retrieval of the IVC filter. Conclusion: Thrombus embolization during CDT is a common phenomenon in patients with proximal DVT. Placement of a retrievable IVC filter during thrombolytic therapy can prevent silent and symptomatic pulmonary embolism. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/1284904
- author
- Kölbel, Tilo LU ; Alhadad, Alaa LU ; Acosta, Stefan LU ; Lindh, Mats LU ; Ivancev, Krasnodar and Gottsäter, Anders LU
- organization
- publishing date
- 2008
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- IVC, inferior vena cava, thrombolysis, deep venous thrombosis, thrombus, hypercoagulable disorder, embolus, filter
- in
- Journal of Endovascular Therapy
- volume
- 15
- issue
- 5
- pages
- 605 - 613
- publisher
- International Society of Endovascular Specialists
- external identifiers
-
- wos:000260232200016
- scopus:56349137725
- ISSN
- 1545-1550
- language
- English
- LU publication?
- yes
- additional info
- The information about affiliations in this record was updated in December 2015. The record was previously connected to the following departments: Unit for Clinical Vascular Disease Research (013242410), Emergency medicine/Medicine/Surgery (013240200), Medical Radiology Unit (013241410)
- id
- 8c90cb1b-44ad-4fb1-80e2-27ebcdcb10c3 (old id 1284904)
- date added to LUP
- 2016-04-01 12:06:25
- date last changed
- 2022-05-14 17:44:18
@article{8c90cb1b-44ad-4fb1-80e2-27ebcdcb10c3, abstract = {{Purpose: To assess the frequency of embolization into retrievable inferior vena cava (IVC) filters during catheter-directed thrombolysis (CDT) and stent placement for acute iliocaval deep venous thrombosis (DVT). Methods: Serial phlebograms from 40 patients (28 women; median age 32 years) consecutively treated with CDT for DVT during a 12-year period were retrospectively evaluated for visible emboli in the IVC filter. Clinical and procedural data extracted from a prospectively maintained database were evaluated to identify predictors for embolization into the filter. Results: Visible emboli were found in 18 (45%) patients. Visible embolization to the IVC filter was less frequent in patients with a hypercoagulable disorder (n=29, 31%) than in patients without a hypercoagulable disorder (n=11, 69%; OR 0.1, 95% Cl 0.02 to 0.56, p=0.006). No patient developed clinical symptomatic pulmonary embolism or a complication related to the placement or retrieval of the IVC filter. Conclusion: Thrombus embolization during CDT is a common phenomenon in patients with proximal DVT. Placement of a retrievable IVC filter during thrombolytic therapy can prevent silent and symptomatic pulmonary embolism.}}, author = {{Kölbel, Tilo and Alhadad, Alaa and Acosta, Stefan and Lindh, Mats and Ivancev, Krasnodar and Gottsäter, Anders}}, issn = {{1545-1550}}, keywords = {{IVC; inferior vena cava; thrombolysis; deep venous thrombosis; thrombus; hypercoagulable disorder; embolus; filter}}, language = {{eng}}, number = {{5}}, pages = {{605--613}}, publisher = {{International Society of Endovascular Specialists}}, series = {{Journal of Endovascular Therapy}}, title = {{Thrombus Embolization Into IVC Filters During Catheter-Directed Thrombolysis for Proximal Deep Venous Thrombosis}}, volume = {{15}}, year = {{2008}}, }