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Long-Term Outcome of Sacrococcygeal Teratoma : A Controlled Cohort Study of Urinary Tract and Bowel Dysfunction and Predictors of Poor Outcome

Hambraeus, Mette LU ; Hagander, Lars LU ; Stenström, Pernilla LU ; Arnbjörnsson, Einar LU and Börjesson, Anna LU (2018) In Journal of Pediatrics 198. p.2-136
Abstract

Objective: To evaluate urinary tract and bowel function in children with sacrococcygeal teratoma, compare the findings with healthy children, and assess predictors of poor outcome. Study design: This was a controlled cohort study of all patients operated for sacrococcygeal teratoma at a tertiary pediatric surgery center, 2000-2013. Urinary and bowel function were compared with healthy control patients matched for age and sex. Perioperative and histopathologic risk factors were analyzed. Results: In total, 17 patients with sacrococcygeal teratoma and 85 healthy control patients were included in the study. Patients with sacrococcygeal teratoma more often were reported to have uncontrolled voiding (12% vs 0%, P <.01), difficulty in... (More)

Objective: To evaluate urinary tract and bowel function in children with sacrococcygeal teratoma, compare the findings with healthy children, and assess predictors of poor outcome. Study design: This was a controlled cohort study of all patients operated for sacrococcygeal teratoma at a tertiary pediatric surgery center, 2000-2013. Urinary and bowel function were compared with healthy control patients matched for age and sex. Perioperative and histopathologic risk factors were analyzed. Results: In total, 17 patients with sacrococcygeal teratoma and 85 healthy control patients were included in the study. Patients with sacrococcygeal teratoma more often were reported to have uncontrolled voiding (12% vs 0%, P <.01), difficulty in bladder emptying (24% vs 0%, P <.001), and pyelonephritis (18% vs 1%, P <.05). Constipation was more common in patients with sacrococcygeal teratoma (47 % vs 14%, P <.05), but the overall bowel function score was equal in the 2 groups. Children with large tumors and immature histology were more likely to have a dysfunctional outcome (P <.05). Conclusions: Uncontrolled voiding, difficulty in bladder emptying, pyelonephritis, and constipation were more common in patients with sacrococcygeal teratoma than in healthy children. Dysfunctional outcome was more prevalent in children with large and immature teratomas.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
bowel dysfunction, complications, follow-up, healthy controls, risk factors, sacrococcygeal teratomas, urinary tract dysfunction
in
Journal of Pediatrics
volume
198
pages
2 - 136
publisher
Academic Press
external identifiers
  • scopus:85045218215
ISSN
0022-3476
DOI
10.1016/j.jpeds.2018.02.031
language
English
LU publication?
yes
id
8dc387c4-9886-47b8-89ef-e78ddcfc4446
date added to LUP
2018-04-23 10:12:29
date last changed
2019-03-19 03:53:27
@article{8dc387c4-9886-47b8-89ef-e78ddcfc4446,
  abstract     = {<p>Objective: To evaluate urinary tract and bowel function in children with sacrococcygeal teratoma, compare the findings with healthy children, and assess predictors of poor outcome. Study design: This was a controlled cohort study of all patients operated for sacrococcygeal teratoma at a tertiary pediatric surgery center, 2000-2013. Urinary and bowel function were compared with healthy control patients matched for age and sex. Perioperative and histopathologic risk factors were analyzed. Results: In total, 17 patients with sacrococcygeal teratoma and 85 healthy control patients were included in the study. Patients with sacrococcygeal teratoma more often were reported to have uncontrolled voiding (12% vs 0%, P &lt;.01), difficulty in bladder emptying (24% vs 0%, P &lt;.001), and pyelonephritis (18% vs 1%, P &lt;.05). Constipation was more common in patients with sacrococcygeal teratoma (47 % vs 14%, P &lt;.05), but the overall bowel function score was equal in the 2 groups. Children with large tumors and immature histology were more likely to have a dysfunctional outcome (P &lt;.05). Conclusions: Uncontrolled voiding, difficulty in bladder emptying, pyelonephritis, and constipation were more common in patients with sacrococcygeal teratoma than in healthy children. Dysfunctional outcome was more prevalent in children with large and immature teratomas.</p>},
  author       = {Hambraeus, Mette and Hagander, Lars and Stenström, Pernilla and Arnbjörnsson, Einar and Börjesson, Anna},
  issn         = {0022-3476},
  keyword      = {bowel dysfunction,complications,follow-up,healthy controls,risk factors,sacrococcygeal teratomas,urinary tract dysfunction},
  language     = {eng},
  month        = {04},
  pages        = {2--136},
  publisher    = {Academic Press},
  series       = {Journal of Pediatrics},
  title        = {Long-Term Outcome of Sacrococcygeal Teratoma : A Controlled Cohort Study of Urinary Tract and Bowel Dysfunction and Predictors of Poor Outcome},
  url          = {http://dx.doi.org/10.1016/j.jpeds.2018.02.031},
  volume       = {198},
  year         = {2018},
}