Real-life assessment of chronic rhinosinusitis patients using mobile technology : The mySinusitisCoach project by EUFOREA
(2020) In Allergy: European Journal of Allergy and Clinical Immunology 75(11). p.2867-2878- Abstract
Background: Chronic rhinosinusitis (CRS) is a chronic inflammatory disease associated with a substantial personal and socioeconomic burden. Monitoring of patient-reported outcomes by mobile technology offers the possibility to better understand real-life burden of CRS. Methods: This study reports on the cross-sectional evaluation of data of 626 users of mySinusitisCoach (mSC), a mobile application for CRS patients. Patient characteristics of mSC users were analysed as well as the level of disease control based on VAS global rhinosinusitis symptom score and adapted EPOS criteria. Results: The mSC cohort represents a heterogeneous group of CRS patients with a diverse pattern of major symptoms. Approximately half of patients reported nasal... (More)
Background: Chronic rhinosinusitis (CRS) is a chronic inflammatory disease associated with a substantial personal and socioeconomic burden. Monitoring of patient-reported outcomes by mobile technology offers the possibility to better understand real-life burden of CRS. Methods: This study reports on the cross-sectional evaluation of data of 626 users of mySinusitisCoach (mSC), a mobile application for CRS patients. Patient characteristics of mSC users were analysed as well as the level of disease control based on VAS global rhinosinusitis symptom score and adapted EPOS criteria. Results: The mSC cohort represents a heterogeneous group of CRS patients with a diverse pattern of major symptoms. Approximately half of patients reported nasal polyps. 47.3% of all CRS patients were uncontrolled based on evaluation of VAS global rhinosinusitis symptom score compared to 40.9% based on adapted EPOS criteria. The impact of CRS on sleep quality and daily life activities was significantly higher in uncontrolled versus well-controlled patients. Half of patients had a history of FESS (functional endoscopic sinus surgery) and reported lower symptom severity compared to patients without a history of FESS, except for patients with a history of more than 3 procedures. Patients with a history of FESS reported higher VAS levels for impaired smell. Conclusion: Real-life data confirm the high disease burden in uncontrolled CRS patients, clearly impacting quality of life. Sinus surgery improves patient-reported outcomes, but not in patients with a history of more than 3 procedures. Mobile technology opens a new era of real-life monitoring, supporting the evolution of care towards precision medicine.
(Less)
- author
- organization
- publishing date
- 2020-11-01
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Mobile health technology, nasal polyp, patient-reported outcome measure, real-world evidence, visual analogue scale
- in
- Allergy: European Journal of Allergy and Clinical Immunology
- volume
- 75
- issue
- 11
- pages
- 12 pages
- publisher
- Wiley-Blackwell
- external identifiers
-
- scopus:85087117443
- pmid:32424899
- ISSN
- 0105-4538
- DOI
- 10.1111/all.14408
- language
- English
- LU publication?
- yes
- id
- 8e9abd5c-10d2-4221-a3d9-56ac447f8d00
- date added to LUP
- 2021-01-15 08:17:57
- date last changed
- 2024-06-14 07:57:54
@article{8e9abd5c-10d2-4221-a3d9-56ac447f8d00,
abstract = {{<p>Background: Chronic rhinosinusitis (CRS) is a chronic inflammatory disease associated with a substantial personal and socioeconomic burden. Monitoring of patient-reported outcomes by mobile technology offers the possibility to better understand real-life burden of CRS. Methods: This study reports on the cross-sectional evaluation of data of 626 users of mySinusitisCoach (mSC), a mobile application for CRS patients. Patient characteristics of mSC users were analysed as well as the level of disease control based on VAS global rhinosinusitis symptom score and adapted EPOS criteria. Results: The mSC cohort represents a heterogeneous group of CRS patients with a diverse pattern of major symptoms. Approximately half of patients reported nasal polyps. 47.3% of all CRS patients were uncontrolled based on evaluation of VAS global rhinosinusitis symptom score compared to 40.9% based on adapted EPOS criteria. The impact of CRS on sleep quality and daily life activities was significantly higher in uncontrolled versus well-controlled patients. Half of patients had a history of FESS (functional endoscopic sinus surgery) and reported lower symptom severity compared to patients without a history of FESS, except for patients with a history of more than 3 procedures. Patients with a history of FESS reported higher VAS levels for impaired smell. Conclusion: Real-life data confirm the high disease burden in uncontrolled CRS patients, clearly impacting quality of life. Sinus surgery improves patient-reported outcomes, but not in patients with a history of more than 3 procedures. Mobile technology opens a new era of real-life monitoring, supporting the evolution of care towards precision medicine.</p>}},
author = {{Seys, Sven F. and De Bont, Shana and Fokkens, Wytske J. and Bachert, Claus and Alobid, Isam and Bernal-Sprekelsen, Manuel and Bjermer, Leif and Callebaut, Ina and Cardell, Lars Olaf and Carrie, Sean and Castelnuovo, Paolo and Cathcart, Russell and Constantinidis, Jannis and Cools, Leen and Cornet, Marjolein and Clement, Gregory and Cox, Tony and Delsupehe, Lieve and Correia-de-Sousa, Jaime and Deneyer, Lauren and De Vos, Geert and Diamant, Zuzana and Doulaptsi, Maria and Gane, Simon and Gevaert, Philippe and Hopkins, Claire and Hox, Valérie and Hummel, Thomas and Hosemann, Werner and Jacobs, Raf and Jorissen, Mark and Kjeldsen, Anette and Landis, Basile N. and Lemmens, Winde and Leunig, Andreas and Lund, Valerie and Mariën, Gert and Mullol, Joaquim and Onerci, Metin and Palkonen, Susanna and Proano, Isabel and Prokopakis, Emmanuel and Ryan, Dermot and Riechelmann, Herbert and Sahlstrand-Johnson, Pernilla and Salmi-Toppila, Sanna and Segboer, Christine and Speleman, Kato and Steinsvik, Andreas and Surda, Pavol and Tomazic, Peter Valentin and Vanderveken, Olivier and Van Gerven, Laura and Van Zele, Thibaut and Verfaillie, Jan and Verhaeghe, Benedicte and Vierstraete, Kathie and Vlaminck, Stephan and Wagenmann, Martin and Pugin, Benoit and Hellings, Peter W.}},
issn = {{0105-4538}},
keywords = {{Mobile health technology; nasal polyp; patient-reported outcome measure; real-world evidence; visual analogue scale}},
language = {{eng}},
month = {{11}},
number = {{11}},
pages = {{2867--2878}},
publisher = {{Wiley-Blackwell}},
series = {{Allergy: European Journal of Allergy and Clinical Immunology}},
title = {{Real-life assessment of chronic rhinosinusitis patients using mobile technology : The mySinusitisCoach project by EUFOREA}},
url = {{http://dx.doi.org/10.1111/all.14408}},
doi = {{10.1111/all.14408}},
volume = {{75}},
year = {{2020}},
}