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Design and fabrication of a conceptual arterial ultrasound phantom capable of exhibiting longitudinal wall movement

Sjöstrand, Sandra LU ; Widerstrom, Alice; Ahlgren, Asa Ryden LU and Cinthio, Magnus LU (2017) In IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 64(1). p.11-18
Abstract

The longitudinal movement of the arterial wall of large human arteries has shown promise to be an independent indicator of vascular health. Despite growing interest in this movement, its nature, causes, and implications are not fully understood, and existing phantoms have failed to show a pure longitudinal movement that is not secondary to the distension. An often overlooked aspect of the arterial wall is the interaction between the different layers. The longitudinal movement of the innermost layers, the intima and media, can be several hundred micrometers in the direction of flow during early systole. This is markedly larger than that of the adventitia, indicating that sliding occurs between the two layers. This feature was... (More)

The longitudinal movement of the arterial wall of large human arteries has shown promise to be an independent indicator of vascular health. Despite growing interest in this movement, its nature, causes, and implications are not fully understood, and existing phantoms have failed to show a pure longitudinal movement that is not secondary to the distension. An often overlooked aspect of the arterial wall is the interaction between the different layers. The longitudinal movement of the innermost layers, the intima and media, can be several hundred micrometers in the direction of flow during early systole. This is markedly larger than that of the adventitia, indicating that sliding occurs between the two layers. This feature was incorporated into a phantom by casting it in two parts. The molds were developed in-house using mainly a 3-D printer, a versatile and easy production method. Additionally, the phantom contains a tapered region. Using the phantom, we were able to demonstrate a pure longitudinal movement; when it was subjected to a pulsatile pressure, the wall displaced 220 μm (SD 40) radially and 560 μm (SD 74) longitudinally distal to the tapering. The motion followed the pressure variations. This paper serves as a guide for phantom production, explaining each step of the process.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Additive manufacturing, artery, longitudinal displacement, phantom, pressure, ultrasound
in
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
volume
64
issue
1
pages
8 pages
publisher
IEEE--Institute of Electrical and Electronics Engineers Inc.
external identifiers
  • scopus:85015189414
  • wos:000395627600002
ISSN
0885-3010
DOI
10.1109/TUFFC.2016.2597246
language
English
LU publication?
yes
id
913e0347-2f93-4149-b66a-b5f551ca9da8
date added to LUP
2017-03-30 09:40:55
date last changed
2017-09-18 11:34:30
@article{913e0347-2f93-4149-b66a-b5f551ca9da8,
  abstract     = {<p>The longitudinal movement of the arterial wall of large human arteries has shown promise to be an independent indicator of vascular health. Despite growing interest in this movement, its nature, causes, and implications are not fully understood, and existing phantoms have failed to show a pure longitudinal movement that is not secondary to the distension. An often overlooked aspect of the arterial wall is the interaction between the different layers. The longitudinal movement of the innermost layers, the intima and media, can be several hundred micrometers in the direction of flow during early systole. This is markedly larger than that of the adventitia, indicating that sliding occurs between the two layers. This feature was incorporated into a phantom by casting it in two parts. The molds were developed in-house using mainly a 3-D printer, a versatile and easy production method. Additionally, the phantom contains a tapered region. Using the phantom, we were able to demonstrate a pure longitudinal movement; when it was subjected to a pulsatile pressure, the wall displaced 220 μm (SD 40) radially and 560 μm (SD 74) longitudinally distal to the tapering. The motion followed the pressure variations. This paper serves as a guide for phantom production, explaining each step of the process.</p>},
  articleno    = {7529216},
  author       = {Sjöstrand, Sandra and Widerstrom, Alice and Ahlgren, Asa Ryden and Cinthio, Magnus},
  issn         = {0885-3010},
  keyword      = {Additive manufacturing,artery,longitudinal displacement,phantom,pressure,ultrasound},
  language     = {eng},
  month        = {01},
  number       = {1},
  pages        = {11--18},
  publisher    = {IEEE--Institute of Electrical and Electronics Engineers Inc.},
  series       = {IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control},
  title        = {Design and fabrication of a conceptual arterial ultrasound phantom capable of exhibiting longitudinal wall movement},
  url          = {http://dx.doi.org/10.1109/TUFFC.2016.2597246},
  volume       = {64},
  year         = {2017},
}