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Valvular heart diseases in immigrants and Swedish-born individuals : a national cohort study

Wändell, Per LU ; Li, Xinjun LU ; Carlsson, Axel C. ; Sundquist, Jan LU and Sundquist, Kristina LU (2022) In Scandinavian Cardiovascular Journal 56(1). p.217-223
Abstract

Objectives. The aim of this study was to analyse the risk of valvular heart diseases among foreign-born individuals in Sweden. Design. This was a nationwide study of individuals aged 18 years of age and older (N = 6,118,649; 2,970,055 men and 3,148,594 women). Valvular heart diseases were defined as at least one registered diagnosis in the National Patient Register between 1 January 1998 and 31 December 2012. Cox regression analysis was used to estimate hazard ratios (HR) with 99% confidence intervals (CI) of incident valvular heart diseases in foreign-born individuals compared to Swedish natives. The Cox regression models were adjusted for age, co-morbidities, and sociodemographic factors. Sub-categories were chronic rheumatic valvular... (More)

Objectives. The aim of this study was to analyse the risk of valvular heart diseases among foreign-born individuals in Sweden. Design. This was a nationwide study of individuals aged 18 years of age and older (N = 6,118,649; 2,970,055 men and 3,148,594 women). Valvular heart diseases were defined as at least one registered diagnosis in the National Patient Register between 1 January 1998 and 31 December 2012. Cox regression analysis was used to estimate hazard ratios (HR) with 99% confidence intervals (CI) of incident valvular heart diseases in foreign-born individuals compared to Swedish natives. The Cox regression models were adjusted for age, co-morbidities, and sociodemographic factors. Sub-categories were chronic rheumatic valvular heart diseases and non-rheumatic valvular heart diseases. Results. There were 64,979 male cases and 59,075 female cases. Fully adjusted HRs (99% CI) were among immigrant men 0.86 (0.82–0.89) and immigrant women 0.96 (0.92–1.00). For chronic rheumatic valvular disease among immigrant men and women, the HRs were 1.62 (1.37–1.92) and 1.75 (1.52–2.00), respectively, and, for non-rheumatic valvular disease among immigrant men 0.83 (0.80–0.87) and immigrant women 0.92 (0.88–0.96). Increased risks for chronic rheumatic valvular disease were found among men from Southern, Eastern and Central Europe, Africa and Asia and among women from Western, Eastern and Central Europe and Africa, Latin America and Asia. Conclusions. We observed lower risks in general of valvular heart disease, but higher risks of chronic rheumatic valvular heart disease in immigrants, which is important in the clinical situation.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
heart failure, immigrants, neighbourhood, rheumatic valvular heart disease, Sex, socioeconomic status, valvular heart disease
in
Scandinavian Cardiovascular Journal
volume
56
issue
1
pages
7 pages
publisher
Taylor & Francis
external identifiers
  • scopus:85133504312
  • pmid:35792712
ISSN
1401-7431
DOI
10.1080/14017431.2022.2095014
language
English
LU publication?
yes
id
919daf9d-2884-4d64-90ce-7f273727e064
date added to LUP
2022-09-13 14:53:50
date last changed
2024-05-30 18:29:47
@article{919daf9d-2884-4d64-90ce-7f273727e064,
  abstract     = {{<p>Objectives. The aim of this study was to analyse the risk of valvular heart diseases among foreign-born individuals in Sweden. Design. This was a nationwide study of individuals aged 18 years of age and older (N = 6,118,649; 2,970,055 men and 3,148,594 women). Valvular heart diseases were defined as at least one registered diagnosis in the National Patient Register between 1 January 1998 and 31 December 2012. Cox regression analysis was used to estimate hazard ratios (HR) with 99% confidence intervals (CI) of incident valvular heart diseases in foreign-born individuals compared to Swedish natives. The Cox regression models were adjusted for age, co-morbidities, and sociodemographic factors. Sub-categories were chronic rheumatic valvular heart diseases and non-rheumatic valvular heart diseases. Results. There were 64,979 male cases and 59,075 female cases. Fully adjusted HRs (99% CI) were among immigrant men 0.86 (0.82–0.89) and immigrant women 0.96 (0.92–1.00). For chronic rheumatic valvular disease among immigrant men and women, the HRs were 1.62 (1.37–1.92) and 1.75 (1.52–2.00), respectively, and, for non-rheumatic valvular disease among immigrant men 0.83 (0.80–0.87) and immigrant women 0.92 (0.88–0.96). Increased risks for chronic rheumatic valvular disease were found among men from Southern, Eastern and Central Europe, Africa and Asia and among women from Western, Eastern and Central Europe and Africa, Latin America and Asia. Conclusions. We observed lower risks in general of valvular heart disease, but higher risks of chronic rheumatic valvular heart disease in immigrants, which is important in the clinical situation.</p>}},
  author       = {{Wändell, Per and Li, Xinjun and Carlsson, Axel C. and Sundquist, Jan and Sundquist, Kristina}},
  issn         = {{1401-7431}},
  keywords     = {{heart failure; immigrants; neighbourhood; rheumatic valvular heart disease; Sex; socioeconomic status; valvular heart disease}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{217--223}},
  publisher    = {{Taylor & Francis}},
  series       = {{Scandinavian Cardiovascular Journal}},
  title        = {{Valvular heart diseases in immigrants and Swedish-born individuals : a national cohort study}},
  url          = {{http://dx.doi.org/10.1080/14017431.2022.2095014}},
  doi          = {{10.1080/14017431.2022.2095014}},
  volume       = {{56}},
  year         = {{2022}},
}