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Increasing Objectivity in Quantitative Analysis in Immune-Histochemistry Biomarker Mapping using Upconverting Nanoparticles

Mickert, Matthias ; Helgstrand, Magnus ; Sekar, Sanathana Konugolu Venkata ; Ma, Hui ; Komolibus, Katarzyna ; Kho, Kiang Wei ; Johansson, Andreas LU ; Wallenborg, Sanna and Andersson-Engels, Stefan LU (2025) 2025 Optical Molecular Probes, Imaging and Drug Delivery, OMP 2025
Abstract

Today immunohistochemistry (IHC) stains molecular biomarkers for treatment stratification. IHC can become increasingly objective by improving sensitivity, quantification and multiplexing capabilities. We use upconverting nanoparticles to achieve this, potentially leading to improved treatment outcomes.

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author
; ; ; ; ; ; ; and
publishing date
type
Contribution to conference
publication status
published
subject
conference name
2025 Optical Molecular Probes, Imaging and Drug Delivery, OMP 2025
conference location
Coronado, United States
conference dates
2025-04-21 - 2025-04-24
external identifiers
  • scopus:105011292936
DOI
10.1364/OMP.2025.OTU1E.2
language
English
LU publication?
no
additional info
Publisher Copyright: © Optica Publishing Group © 2025 The Author(s).
id
9238cce3-9753-4243-a9bb-b0dda2a7463d
date added to LUP
2026-01-21 13:50:40
date last changed
2026-01-21 13:51:49
@misc{9238cce3-9753-4243-a9bb-b0dda2a7463d,
  abstract     = {{<p>Today immunohistochemistry (IHC) stains molecular biomarkers for treatment stratification. IHC can become increasingly objective by improving sensitivity, quantification and multiplexing capabilities. We use upconverting nanoparticles to achieve this, potentially leading to improved treatment outcomes.</p>}},
  author       = {{Mickert, Matthias and Helgstrand, Magnus and Sekar, Sanathana Konugolu Venkata and Ma, Hui and Komolibus, Katarzyna and Kho, Kiang Wei and Johansson, Andreas and Wallenborg, Sanna and Andersson-Engels, Stefan}},
  language     = {{eng}},
  title        = {{Increasing Objectivity in Quantitative Analysis in Immune-Histochemistry Biomarker Mapping using Upconverting Nanoparticles}},
  url          = {{http://dx.doi.org/10.1364/OMP.2025.OTU1E.2}},
  doi          = {{10.1364/OMP.2025.OTU1E.2}},
  year         = {{2025}},
}