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A biopsychosocial perspective on endometriosis : the importance of psychological inflexibility

Åkerblom, Sophia LU ; Peppler Jönsson, Ingrid ; Ringqvist, Åsa LU ; Nordengren, Johanna LU and Zhao, Xiang (2026) In Archives of Gynecology and Obstetrics 313(1).
Abstract

Introduction: Treatment strategies for endometriosis have traditionally been biomedical. There is a need for a more multidimensional understanding of endometriosis and more targeted and individualized treatment interventions, including psychological approaches. Methods: The aims of this study were twofold: (1) to identify key biopsychosocial characteristics in individuals attending a tertiary clinic for endometriosis and (2) to inform the development of future, targeted, and efficacious interventions by examining the importance of psychological processes central to two scientific models, pain catastrophizing and fear of movement from the fear-avoidance model, and psychological inflexibility from the psychological flexibility model.... (More)

Introduction: Treatment strategies for endometriosis have traditionally been biomedical. There is a need for a more multidimensional understanding of endometriosis and more targeted and individualized treatment interventions, including psychological approaches. Methods: The aims of this study were twofold: (1) to identify key biopsychosocial characteristics in individuals attending a tertiary clinic for endometriosis and (2) to inform the development of future, targeted, and efficacious interventions by examining the importance of psychological processes central to two scientific models, pain catastrophizing and fear of movement from the fear-avoidance model, and psychological inflexibility from the psychological flexibility model. Results: Psychosocial variables, more specifically perceived control and powerlessness, social support, and depression, were of particular importance to the symptom structure in this patient population. In contrast, biological factors appeared to have low relevance within this network. When aiming to inform the development of future, promising psychological interventions for endometriosis, psychological inflexibility emerged as the most important psychological process variable in the symptom network. Conclusions: A multidimensional approach based on the biopsychosocial model appears valuable for understanding endometriosis. Treatment interventions grounded in the psychological flexibility model may hold promise for this patient population, a possibility that warrants further investigation in future studies.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Biopsychosocial model, Endometriosis, Kinesiophobia, Pain catastrophizing, Psychological inflexibility
in
Archives of Gynecology and Obstetrics
volume
313
issue
1
article number
108
publisher
Springer
external identifiers
  • scopus:105030997988
  • pmid:41733684
ISSN
0932-0067
DOI
10.1007/s00404-025-08276-0
language
English
LU publication?
yes
additional info
Publisher Copyright: © The Author(s) 2026.
id
930590b9-2cba-4083-ad4c-52e6a9a5ba9a
date added to LUP
2026-04-07 13:30:55
date last changed
2026-06-02 19:59:39
@article{930590b9-2cba-4083-ad4c-52e6a9a5ba9a,
  abstract     = {{<p>Introduction: Treatment strategies for endometriosis have traditionally been biomedical. There is a need for a more multidimensional understanding of endometriosis and more targeted and individualized treatment interventions, including psychological approaches. Methods: The aims of this study were twofold: (1) to identify key biopsychosocial characteristics in individuals attending a tertiary clinic for endometriosis and (2) to inform the development of future, targeted, and efficacious interventions by examining the importance of psychological processes central to two scientific models, pain catastrophizing and fear of movement from the fear-avoidance model, and psychological inflexibility from the psychological flexibility model. Results: Psychosocial variables, more specifically perceived control and powerlessness, social support, and depression, were of particular importance to the symptom structure in this patient population. In contrast, biological factors appeared to have low relevance within this network. When aiming to inform the development of future, promising psychological interventions for endometriosis, psychological inflexibility emerged as the most important psychological process variable in the symptom network. Conclusions: A multidimensional approach based on the biopsychosocial model appears valuable for understanding endometriosis. Treatment interventions grounded in the psychological flexibility model may hold promise for this patient population, a possibility that warrants further investigation in future studies.</p>}},
  author       = {{Åkerblom, Sophia and Peppler Jönsson, Ingrid and Ringqvist, Åsa and Nordengren, Johanna and Zhao, Xiang}},
  issn         = {{0932-0067}},
  keywords     = {{Biopsychosocial model; Endometriosis; Kinesiophobia; Pain catastrophizing; Psychological inflexibility}},
  language     = {{eng}},
  number       = {{1}},
  publisher    = {{Springer}},
  series       = {{Archives of Gynecology and Obstetrics}},
  title        = {{A biopsychosocial perspective on endometriosis : the importance of psychological inflexibility}},
  url          = {{http://dx.doi.org/10.1007/s00404-025-08276-0}},
  doi          = {{10.1007/s00404-025-08276-0}},
  volume       = {{313}},
  year         = {{2026}},
}