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Review of life science applications using submicron O-PTIR and simultaneous Raman microscopy: a new paradigm in vibrational spectroscopy

Kanziz, Mustafa ; Spadea, Alice ; Nallala, Jayakrupakar ; Lima, Cassio ; Muhamadali, Howbeer ; Denbigh, Joanna ; Lawrence, Jayne ; Bakir, Gorkem ; Gardner, Peter and Stone, Nick , et al. (2021) SPIE BIOS In Proceedings of SPIE 11656.
Abstract
The recent advent of Optical Photothermal IR (O-PTIR), has enabled for the first time, submicron infrared microscopy in far-field reflection mode with the combination of Raman for simultaneous, correlative IR+Raman microscopy. These unique and exciting synergistic capabilities are now spawning interest in life science application. A broad range of life science applications, otherwise impossible with traditional FTIR/QCL microscopy, will be presented, ranging from live cell imaging in water, to ultra-high resolution images of breast tissue calcifications, amyloid aggregates in neurons (neurites and dendritic spines), individual collagen fibrils with polarized IR and individual isotopically labelled bacterial cells and more.
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organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
host publication
Advanced Chemical Microscopy for Life Science and Translational Medicine 2021
series title
Proceedings of SPIE
volume
11656
article number
1165617
publisher
SPIE
conference name
SPIE BIOS
conference dates
2021-03-06 - 2021-04-12
ISSN
1605-7422
2410-9045
ISBN
9781510641471
DOI
10.1117/12.2578662
language
English
LU publication?
yes
id
93752777-5155-4656-bed5-d8bd296310db
date added to LUP
2021-04-01 21:55:07
date last changed
2023-08-07 15:33:37
@inproceedings{93752777-5155-4656-bed5-d8bd296310db,
  abstract     = {{The recent advent of Optical Photothermal IR (O-PTIR), has enabled for the first time, submicron infrared microscopy in far-field reflection mode with the combination of Raman for simultaneous, correlative IR+Raman microscopy. These unique and exciting synergistic capabilities are now spawning interest in life science application. A broad range of life science applications, otherwise impossible with traditional FTIR/QCL microscopy, will be presented, ranging from live cell imaging in water, to ultra-high resolution images of breast tissue calcifications, amyloid aggregates in neurons (neurites and dendritic spines), individual collagen fibrils with polarized IR and individual isotopically labelled bacterial cells and more.}},
  author       = {{Kanziz, Mustafa and Spadea, Alice and Nallala, Jayakrupakar and Lima, Cassio and Muhamadali, Howbeer and Denbigh, Joanna and Lawrence, Jayne and Bakir, Gorkem and Gardner, Peter and Stone, Nick and Goodacre, Roy and Gough, Kathleen and Klementieva, Oxana}},
  booktitle    = {{Advanced Chemical Microscopy for Life Science and Translational Medicine 2021}},
  isbn         = {{9781510641471}},
  issn         = {{1605-7422}},
  language     = {{eng}},
  month        = {{03}},
  publisher    = {{SPIE}},
  series       = {{Proceedings of SPIE}},
  title        = {{Review of life science applications using submicron O-PTIR and simultaneous Raman microscopy: a new paradigm in vibrational spectroscopy}},
  url          = {{http://dx.doi.org/10.1117/12.2578662}},
  doi          = {{10.1117/12.2578662}},
  volume       = {{11656}},
  year         = {{2021}},
}