Review of life science applications using submicron O-PTIR and simultaneous Raman microscopy: a new paradigm in vibrational spectroscopy
(2021) SPIE BIOS In Proceedings of SPIE 11656.- Abstract
- The recent advent of Optical Photothermal IR (O-PTIR), has enabled for the first time, submicron infrared microscopy in far-field reflection mode with the combination of Raman for simultaneous, correlative IR+Raman microscopy. These unique and exciting synergistic capabilities are now spawning interest in life science application. A broad range of life science applications, otherwise impossible with traditional FTIR/QCL microscopy, will be presented, ranging from live cell imaging in water, to ultra-high resolution images of breast tissue calcifications, amyloid aggregates in neurons (neurites and dendritic spines), individual collagen fibrils with polarized IR and individual isotopically labelled bacterial cells and more.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/93752777-5155-4656-bed5-d8bd296310db
- author
- organization
- publishing date
- 2021-03-05
- type
- Chapter in Book/Report/Conference proceeding
- publication status
- published
- subject
- host publication
- Advanced Chemical Microscopy for Life Science and Translational Medicine 2021
- series title
- Proceedings of SPIE
- volume
- 11656
- article number
- 1165617
- publisher
- SPIE
- conference name
- SPIE BIOS
- conference dates
- 2021-03-06 - 2021-04-12
- ISSN
- 1605-7422
- 2410-9045
- ISBN
- 9781510641471
- DOI
- 10.1117/12.2578662
- language
- English
- LU publication?
- yes
- id
- 93752777-5155-4656-bed5-d8bd296310db
- date added to LUP
- 2021-04-01 21:55:07
- date last changed
- 2023-08-07 15:33:37
@inproceedings{93752777-5155-4656-bed5-d8bd296310db, abstract = {{The recent advent of Optical Photothermal IR (O-PTIR), has enabled for the first time, submicron infrared microscopy in far-field reflection mode with the combination of Raman for simultaneous, correlative IR+Raman microscopy. These unique and exciting synergistic capabilities are now spawning interest in life science application. A broad range of life science applications, otherwise impossible with traditional FTIR/QCL microscopy, will be presented, ranging from live cell imaging in water, to ultra-high resolution images of breast tissue calcifications, amyloid aggregates in neurons (neurites and dendritic spines), individual collagen fibrils with polarized IR and individual isotopically labelled bacterial cells and more.}}, author = {{Kanziz, Mustafa and Spadea, Alice and Nallala, Jayakrupakar and Lima, Cassio and Muhamadali, Howbeer and Denbigh, Joanna and Lawrence, Jayne and Bakir, Gorkem and Gardner, Peter and Stone, Nick and Goodacre, Roy and Gough, Kathleen and Klementieva, Oxana}}, booktitle = {{Advanced Chemical Microscopy for Life Science and Translational Medicine 2021}}, isbn = {{9781510641471}}, issn = {{1605-7422}}, language = {{eng}}, month = {{03}}, publisher = {{SPIE}}, series = {{Proceedings of SPIE}}, title = {{Review of life science applications using submicron O-PTIR and simultaneous Raman microscopy: a new paradigm in vibrational spectroscopy}}, url = {{http://dx.doi.org/10.1117/12.2578662}}, doi = {{10.1117/12.2578662}}, volume = {{11656}}, year = {{2021}}, }