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Endograft Repair of Complicated Acute Type B Aortic Dissections

Sobocinski, J. ; Dias, Nuno LU orcid ; Berger, L. ; Midulla, M. ; Hertault, A. ; Sonesson, Björn LU ; Resch, Tim LU and Haulon, S. (2013) In European Journal of Vascular and Endovascular Surgery 45(5). p.468-474
Abstract
Objectives: This study aims to assess patient outcomes and aortic remodelling following coverage of the proximal entry tear with an endograft in complicated acute type B aortic dissections (caTBADs). Material and methods: All patients with caTBAD treated with a thoracic endograft in three high-volume vascular centres were retrospectively studied. Inclusion criteria were branch-vessel malperfusion, impending or overt aortic rupture, maximal aortic diameter >= 40 mm and persistent pain or uncontrolled hypertension despite maximum pharmacological treatment. Postoperative aortic remodelling was evaluated using computed tomography angiography (CTA). on a three-dimensional (3D) imaging workstation. Results: A total of 52 patients (71% male,... (More)
Objectives: This study aims to assess patient outcomes and aortic remodelling following coverage of the proximal entry tear with an endograft in complicated acute type B aortic dissections (caTBADs). Material and methods: All patients with caTBAD treated with a thoracic endograft in three high-volume vascular centres were retrospectively studied. Inclusion criteria were branch-vessel malperfusion, impending or overt aortic rupture, maximal aortic diameter >= 40 mm and persistent pain or uncontrolled hypertension despite maximum pharmacological treatment. Postoperative aortic remodelling was evaluated using computed tomography angiography (CTA). on a three-dimensional (3D) imaging workstation. Results: A total of 52 patients (71% male, median age 65 years) were included in the study. Median inclusion criteria per patient were 2 (range 1-4). Branch-vessel malperfusion was diagnosed in 42% and impending aortic rupture in 33% of 52 patients. Median follow-up was 25 months (range 2-109 months). The 30-day mortality rate was 9.6% (5/52); patient survival according to the Kaplan-Meier method was 90.4% at 12 months and 87.6% at 24 months. Secondary interventions were performed in seven patients a median of 3 days after the initial procedure (range 2-865). Imaging follow-up at 12 months was performed in 36 patients (69%): 75% presented stable or shrinking (>5 mm) maximal aortic diameters and 86% had a completely thrombosed false lumen (vs. 5% before initial procedure) at thoracic level. Conclusion: Endograft treatment of complicated caTBAD is associated with favourable early outcomes and possibly promotes aortic remodelling in the majority of patients. (C) 2013 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved. (Less)
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author
; ; ; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Aortic dissection, Acute, Endograft
in
European Journal of Vascular and Endovascular Surgery
volume
45
issue
5
pages
468 - 474
publisher
Elsevier
external identifiers
  • wos:000319175300014
  • scopus:84876418990
  • pmid:23433951
ISSN
1532-2165
DOI
10.1016/j.ejvs.2013.01.031
language
English
LU publication?
yes
id
953f4270-0042-4e3a-bbcf-3754c021acbe (old id 3932258)
date added to LUP
2016-04-01 13:10:49
date last changed
2022-01-27 17:45:33
@article{953f4270-0042-4e3a-bbcf-3754c021acbe,
  abstract     = {{Objectives: This study aims to assess patient outcomes and aortic remodelling following coverage of the proximal entry tear with an endograft in complicated acute type B aortic dissections (caTBADs). Material and methods: All patients with caTBAD treated with a thoracic endograft in three high-volume vascular centres were retrospectively studied. Inclusion criteria were branch-vessel malperfusion, impending or overt aortic rupture, maximal aortic diameter >= 40 mm and persistent pain or uncontrolled hypertension despite maximum pharmacological treatment. Postoperative aortic remodelling was evaluated using computed tomography angiography (CTA). on a three-dimensional (3D) imaging workstation. Results: A total of 52 patients (71% male, median age 65 years) were included in the study. Median inclusion criteria per patient were 2 (range 1-4). Branch-vessel malperfusion was diagnosed in 42% and impending aortic rupture in 33% of 52 patients. Median follow-up was 25 months (range 2-109 months). The 30-day mortality rate was 9.6% (5/52); patient survival according to the Kaplan-Meier method was 90.4% at 12 months and 87.6% at 24 months. Secondary interventions were performed in seven patients a median of 3 days after the initial procedure (range 2-865). Imaging follow-up at 12 months was performed in 36 patients (69%): 75% presented stable or shrinking (>5 mm) maximal aortic diameters and 86% had a completely thrombosed false lumen (vs. 5% before initial procedure) at thoracic level. Conclusion: Endograft treatment of complicated caTBAD is associated with favourable early outcomes and possibly promotes aortic remodelling in the majority of patients. (C) 2013 European Society for Vascular Surgery. Published by Elsevier Ltd. All rights reserved.}},
  author       = {{Sobocinski, J. and Dias, Nuno and Berger, L. and Midulla, M. and Hertault, A. and Sonesson, Björn and Resch, Tim and Haulon, S.}},
  issn         = {{1532-2165}},
  keywords     = {{Aortic dissection; Acute; Endograft}},
  language     = {{eng}},
  number       = {{5}},
  pages        = {{468--474}},
  publisher    = {{Elsevier}},
  series       = {{European Journal of Vascular and Endovascular Surgery}},
  title        = {{Endograft Repair of Complicated Acute Type B Aortic Dissections}},
  url          = {{http://dx.doi.org/10.1016/j.ejvs.2013.01.031}},
  doi          = {{10.1016/j.ejvs.2013.01.031}},
  volume       = {{45}},
  year         = {{2013}},
}