Advanced

Atrial fibrillation in immigrants under the age of 45 y in Sweden

Wändell, Per LU ; Carlsson, Axel C; Li, Xinjun LU ; Gasevic, Danijela; Ärnlöv, Johan; Holzmann, Martin J; Sundquist, Jan LU and Sundquist, Kristina LU (2018) In International Health p.1-10
Abstract

Aim: To study association between country of birth and risk of first-onset atrial fibrillation (AF) in first- and second-generation immigrants to Sweden under 45 y of age.

Methods: The study population included all individuals (n = 3 248 457) under the age of 45 y in Sweden, including immigrants (n = 722 249). AF was defined as first registered diagnosis in the National Patient Register. Association between country of birth and risk of AF was assessed by Cox regression, calculating HRs and 95% CIs, using Swedish-born individuals as referents. All models were stratified by sex, and in different models were adjusted for age, area of residence in Sweden, educational level, marital status, neighbourhood socioeconomic status and... (More)

Aim: To study association between country of birth and risk of first-onset atrial fibrillation (AF) in first- and second-generation immigrants to Sweden under 45 y of age.

Methods: The study population included all individuals (n = 3 248 457) under the age of 45 y in Sweden, including immigrants (n = 722 249). AF was defined as first registered diagnosis in the National Patient Register. Association between country of birth and risk of AF was assessed by Cox regression, calculating HRs and 95% CIs, using Swedish-born individuals as referents. All models were stratified by sex, and in different models were adjusted for age, area of residence in Sweden, educational level, marital status, neighbourhood socioeconomic status and co-morbidity(ies).

Results: A higher fully adjusted HR of incident AF was found in the total sample of first-generation immigrants, 1.44 (95% CI 1.35 to 1.54), in males born in Denmark, Lebanon and Iraq, and in females born in Turkey and Iraq. Lower HRs were found in male and female immigrants from Latin America and Iran, and female immigrants from Finland. Among second-generation immigrants, the fully adjusted HR was significantly lower, 0.70 (95% CI 0.58 to 0.83).

Conclusions: Clinicians may show a greater awareness of AF in some groups of younger immigrants to enable early diagnosis.

(Less)
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
epub
subject
in
International Health
pages
1 - 10
publisher
Oxford University Press
ISSN
1876-3405
DOI
10.1093/inthealth/ihy075
language
English
LU publication?
yes
id
955721b2-c83e-4cbe-9ce6-ed9a4a030f4e
date added to LUP
2019-01-30 10:45:31
date last changed
2019-02-08 09:35:57
@article{955721b2-c83e-4cbe-9ce6-ed9a4a030f4e,
  abstract     = {<p>Aim: To study association between country of birth and risk of first-onset atrial fibrillation (AF) in first- and second-generation immigrants to Sweden under 45 y of age.</p><p>Methods: The study population included all individuals (n = 3 248 457) under the age of 45 y in Sweden, including immigrants (n = 722 249). AF was defined as first registered diagnosis in the National Patient Register. Association between country of birth and risk of AF was assessed by Cox regression, calculating HRs and 95% CIs, using Swedish-born individuals as referents. All models were stratified by sex, and in different models were adjusted for age, area of residence in Sweden, educational level, marital status, neighbourhood socioeconomic status and co-morbidity(ies).</p><p>Results: A higher fully adjusted HR of incident AF was found in the total sample of first-generation immigrants, 1.44 (95% CI 1.35 to 1.54), in males born in Denmark, Lebanon and Iraq, and in females born in Turkey and Iraq. Lower HRs were found in male and female immigrants from Latin America and Iran, and female immigrants from Finland. Among second-generation immigrants, the fully adjusted HR was significantly lower, 0.70 (95% CI 0.58 to 0.83).</p><p>Conclusions: Clinicians may show a greater awareness of AF in some groups of younger immigrants to enable early diagnosis.</p>},
  author       = {Wändell, Per and Carlsson, Axel C and Li, Xinjun and Gasevic, Danijela and Ärnlöv, Johan and Holzmann, Martin J and Sundquist, Jan and Sundquist, Kristina},
  issn         = {1876-3405},
  language     = {eng},
  month        = {10},
  pages        = {1--10},
  publisher    = {Oxford University Press},
  series       = {International Health},
  title        = {Atrial fibrillation in immigrants under the age of 45 y in Sweden},
  url          = {http://dx.doi.org/10.1093/inthealth/ihy075},
  year         = {2018},
}