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Laparoscopic hepatectomy for HCC in elderly patients : risks and feasibility

Amato, Bruno; Aprea, Giovanni; de Rosa, Davide; Milone, Marco; Di Domenico, Lorenza; Amato, Maurizio; Compagna, Rita; Santoro, Mario; Johnson, Louis Banka LU and Sanguinetti, Alessandro, et al. (2017) In Aging clinical and experimental research 29(Suppl. 1). p.179-183
Abstract

Background: Laparoscopic liver resection (LLR) appears to be safe and effective as open liver resection (OLR) for hepatocellular carcinoma (HCC). However, studies comparing LLR with ORL in elderly patients are limited. The purpose of this study is to compare the clinical outcomes of LLR versus OLR for HCC in elderly patients. Methods: A retrospective analysis was made comparing laparoscopic (n = 11) and open (n = 18) liver resections in elderly patients performed at the University of Naples “Federico II” between January 2010 and December 2014. Demographic data, operative and postoperative outcomes were analyzed. Results: Demographic and tumor characteristics of laparoscopic and OLRs were similar. There were also no significant... (More)

Background: Laparoscopic liver resection (LLR) appears to be safe and effective as open liver resection (OLR) for hepatocellular carcinoma (HCC). However, studies comparing LLR with ORL in elderly patients are limited. The purpose of this study is to compare the clinical outcomes of LLR versus OLR for HCC in elderly patients. Methods: A retrospective analysis was made comparing laparoscopic (n = 11) and open (n = 18) liver resections in elderly patients performed at the University of Naples “Federico II” between January 2010 and December 2014. Demographic data, operative and postoperative outcomes were analyzed. Results: Demographic and tumor characteristics of laparoscopic and OLRs were similar. There were also no significant differences in operating room time. Patients undergoing OLR had increased rate of minor complications (33 vs. 0%), longer lengths of stay (6 vs. 3 days) and higher blood loss (310 ± 84 vs. 198 ± 34 ml). There were no significant differences in major complication rates or 90-day mortality. Discussion: LLR is safe and feasible as OLR for treatment of HCC in selected elderly patients.

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Contribution to journal
publication status
published
subject
keywords
Elder, HCC, Hepathectomy, Laparoscopic surgery
in
Aging clinical and experimental research
volume
29
issue
Suppl. 1
pages
179 - 183
publisher
Kurtis
external identifiers
  • scopus:85001022151
  • wos:000396128300027
ISSN
1594-0667
DOI
10.1007/s40520-016-0675-6
language
English
LU publication?
yes
id
95b0c506-150c-4ab4-bd9c-4c57823ff5d1
date added to LUP
2016-12-28 09:38:31
date last changed
2018-01-07 11:42:46
@article{95b0c506-150c-4ab4-bd9c-4c57823ff5d1,
  abstract     = {<p>Background: Laparoscopic liver resection (LLR) appears to be safe and effective as open liver resection (OLR) for hepatocellular carcinoma (HCC). However, studies comparing LLR with ORL in elderly patients are limited. The purpose of this study is to compare the clinical outcomes of LLR versus OLR for HCC in elderly patients. Methods: A retrospective analysis was made comparing laparoscopic (n = 11) and open (n = 18) liver resections in elderly patients performed at the University of Naples “Federico II” between January 2010 and December 2014. Demographic data, operative and postoperative outcomes were analyzed. Results: Demographic and tumor characteristics of laparoscopic and OLRs were similar. There were also no significant differences in operating room time. Patients undergoing OLR had increased rate of minor complications (33 vs. 0%), longer lengths of stay (6 vs. 3 days) and higher blood loss (310 ± 84 vs. 198 ± 34 ml). There were no significant differences in major complication rates or 90-day mortality. Discussion: LLR is safe and feasible as OLR for treatment of HCC in selected elderly patients.</p>},
  author       = {Amato, Bruno and Aprea, Giovanni and de Rosa, Davide and Milone, Marco and Di Domenico, Lorenza and Amato, Maurizio and Compagna, Rita and Santoro, Mario and Johnson, Louis Banka and Sanguinetti, Alessandro and Polistena, Andrea and Avenia, Nicola},
  issn         = {1594-0667},
  keyword      = {Elder,HCC,Hepathectomy,Laparoscopic surgery},
  language     = {eng},
  number       = {Suppl. 1},
  pages        = {179--183},
  publisher    = {Kurtis},
  series       = {Aging clinical and experimental research},
  title        = {Laparoscopic hepatectomy for HCC in elderly patients : risks and feasibility},
  url          = {http://dx.doi.org/10.1007/s40520-016-0675-6},
  volume       = {29},
  year         = {2017},
}