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Current progress of adhesins as vaccine candidates for Moraxella catarrhalis

Tan, Thuan Tong LU and Riesbeck, Kristian LU orcid (2007) In Expert Review of Vaccines 6(6). p.949-956
Abstract
Moraxello catorrhalis is an emerging pathogen and all isolates are now considered beta-lactamase producing. Potential further use of vaccines against Streptococcus pneumoniae and nontypeable Haemophilus influenzae means that M. catarrhalis might be thrust further into the limelight. However, a vaccine has not yet been designed. In this review, the progress of M. catarrhalis adhesins as vaccine candidates is discussed with a focus on various candidate antigens that spanned those discovered more than 10 years ago, for example, the ubiquitous surface proteins to newer antigens, such as the Moraxella IgD-binding hemagglutinin.
Please use this url to cite or link to this publication:
author
and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
surface protein A1/A2, ubiquitous, outer membrane protein CD, OLpA, IgD binding protein/hag, Moraxella, Moraxella catarrhalis, mcmA, filamentous hemagglutinin, McaP
in
Expert Review of Vaccines
volume
6
issue
6
pages
949 - 956
publisher
Future Drugs Ltd
external identifiers
  • wos:000251556200015
  • pmid:18377357
  • scopus:37149055304
  • pmid:18377357
ISSN
1744-8395
DOI
10.1586/14760584.6.6.949
language
English
LU publication?
yes
id
8c7798f3-da0c-469d-a38e-27854f15899e (old id 966316)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/18377357?dopt=Abstract
date added to LUP
2016-04-01 12:22:51
date last changed
2025-04-04 13:55:03
@article{8c7798f3-da0c-469d-a38e-27854f15899e,
  abstract     = {{Moraxello catorrhalis is an emerging pathogen and all isolates are now considered beta-lactamase producing. Potential further use of vaccines against Streptococcus pneumoniae and nontypeable Haemophilus influenzae means that M. catarrhalis might be thrust further into the limelight. However, a vaccine has not yet been designed. In this review, the progress of M. catarrhalis adhesins as vaccine candidates is discussed with a focus on various candidate antigens that spanned those discovered more than 10 years ago, for example, the ubiquitous surface proteins to newer antigens, such as the Moraxella IgD-binding hemagglutinin.}},
  author       = {{Tan, Thuan Tong and Riesbeck, Kristian}},
  issn         = {{1744-8395}},
  keywords     = {{surface protein A1/A2; ubiquitous; outer membrane protein CD; OLpA; IgD binding protein/hag; Moraxella; Moraxella catarrhalis; mcmA; filamentous hemagglutinin; McaP}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{949--956}},
  publisher    = {{Future Drugs Ltd}},
  series       = {{Expert Review of Vaccines}},
  title        = {{Current progress of adhesins as vaccine candidates for Moraxella catarrhalis}},
  url          = {{http://dx.doi.org/10.1586/14760584.6.6.949}},
  doi          = {{10.1586/14760584.6.6.949}},
  volume       = {{6}},
  year         = {{2007}},
}