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Current progress of adhesins as vaccine candidates for Moraxella catarrhalis

Tan, Thuan Tong LU and Riesbeck, Kristian LU (2007) In Expert Review of Vaccines 6(6). p.949-956
Abstract
Moraxello catorrhalis is an emerging pathogen and all isolates are now considered beta-lactamase producing. Potential further use of vaccines against Streptococcus pneumoniae and nontypeable Haemophilus influenzae means that M. catarrhalis might be thrust further into the limelight. However, a vaccine has not yet been designed. In this review, the progress of M. catarrhalis adhesins as vaccine candidates is discussed with a focus on various candidate antigens that spanned those discovered more than 10 years ago, for example, the ubiquitous surface proteins to newer antigens, such as the Moraxella IgD-binding hemagglutinin.
Please use this url to cite or link to this publication:
author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
surface protein A1/A2, ubiquitous, outer membrane protein CD, OLpA, IgD binding protein/hag, Moraxella, Moraxella catarrhalis, mcmA, filamentous hemagglutinin, McaP
in
Expert Review of Vaccines
volume
6
issue
6
pages
949 - 956
publisher
Future Drugs Ltd
external identifiers
  • wos:000251556200015
  • pmid:18377357
  • scopus:37149055304
ISSN
1744-8395
DOI
10.1586/14760584.6.6.949
language
English
LU publication?
yes
id
8c7798f3-da0c-469d-a38e-27854f15899e (old id 966316)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/18377357?dopt=Abstract
date added to LUP
2008-01-30 09:28:21
date last changed
2017-09-03 03:52:56
@article{8c7798f3-da0c-469d-a38e-27854f15899e,
  abstract     = {Moraxello catorrhalis is an emerging pathogen and all isolates are now considered beta-lactamase producing. Potential further use of vaccines against Streptococcus pneumoniae and nontypeable Haemophilus influenzae means that M. catarrhalis might be thrust further into the limelight. However, a vaccine has not yet been designed. In this review, the progress of M. catarrhalis adhesins as vaccine candidates is discussed with a focus on various candidate antigens that spanned those discovered more than 10 years ago, for example, the ubiquitous surface proteins to newer antigens, such as the Moraxella IgD-binding hemagglutinin.},
  author       = {Tan, Thuan Tong and Riesbeck, Kristian},
  issn         = {1744-8395},
  keyword      = {surface protein A1/A2,ubiquitous,outer membrane protein CD,OLpA,IgD binding protein/hag,Moraxella,Moraxella catarrhalis,mcmA,filamentous hemagglutinin,McaP},
  language     = {eng},
  number       = {6},
  pages        = {949--956},
  publisher    = {Future Drugs Ltd},
  series       = {Expert Review of Vaccines},
  title        = {Current progress of adhesins as vaccine candidates for Moraxella catarrhalis},
  url          = {http://dx.doi.org/10.1586/14760584.6.6.949},
  volume       = {6},
  year         = {2007},
}