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T-regulatory cells-Triumph of perseverance : The Crafoord Prize for Polyarthritis in 2017

Wollheim, Frank A. LU (2017) In Seminars in Arthritis and Rheumatism
Abstract

The Crafoord Prize in Polyarthritis ranks as one of the most prestigious prizes and can be awarded only if the Royal Swedish Academy of Sciences decides the likelihood of prize worthy progress in the field, and at most every 4th year. This has happened only four times since 1982. This year the 5th Laureates were Shimon Sakaguchi, Fred Ramsdell, and Alexander Rudensky with the motivation "for their discoveries relating to regulatory T cells, which counteract harmful immune reactions in arthritis and other autoimmune diseases". Here I review the history of their contributions and its impact in rheumatology.

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author
organization
publishing date
type
Contribution to journal
publication status
epub
subject
keywords
Autoimmunity, CTLA-4, FoxP3, IPEX, Low dose IL-2, Regulatory T cells, Scurfy
in
Seminars in Arthritis and Rheumatism
publisher
W.B. Saunders Co.
external identifiers
  • scopus:85031426453
ISSN
0049-0172
DOI
10.1016/j.semarthrit.2017.08.010
language
English
LU publication?
yes
id
97f601cf-6498-4737-90ee-bffe2c358398
date added to LUP
2017-11-08 10:31:31
date last changed
2018-01-07 12:25:20
@article{97f601cf-6498-4737-90ee-bffe2c358398,
  abstract     = {<p>The Crafoord Prize in Polyarthritis ranks as one of the most prestigious prizes and can be awarded only if the Royal Swedish Academy of Sciences decides the likelihood of prize worthy progress in the field, and at most every 4th year. This has happened only four times since 1982. This year the 5th Laureates were Shimon Sakaguchi, Fred Ramsdell, and Alexander Rudensky with the motivation "for their discoveries relating to regulatory T cells, which counteract harmful immune reactions in arthritis and other autoimmune diseases". Here I review the history of their contributions and its impact in rheumatology.</p>},
  author       = {Wollheim, Frank A.},
  issn         = {0049-0172},
  keyword      = {Autoimmunity,CTLA-4,FoxP3,IPEX,Low dose IL-2,Regulatory T cells,Scurfy},
  language     = {eng},
  month        = {09},
  publisher    = {W.B. Saunders Co.},
  series       = {Seminars in Arthritis and Rheumatism},
  title        = {T-regulatory cells-Triumph of perseverance : The Crafoord Prize for Polyarthritis in 2017},
  url          = {http://dx.doi.org/10.1016/j.semarthrit.2017.08.010},
  year         = {2017},
}