Metabolic engineering of Saccharomyces cerevisiae for xylose utilization.
(2001) In Advances in Biochemical Engineering, Biotechnology 73. p.53-84- Abstract
- Metabolic engineering of Saccharomyces cerevisiae for ethanolic fermentation of xylose is summarized with emphasis on progress made during the last decade. Advances in xylose transport, initial xylose metabolism, selection of host strains, transformation and classical breeding techniques applied to industrial polyploid strains as well as modeling of xylose metabolism are discussed. The production and composition of the substrates--lignocellulosic hydrolysates--is briefly summarized. In a future outlook iterative strategies involving the techniques of classical breeding, quantitative physiology, proteomics, DNA micro arrays, and genetic engineering are proposed for the development of efficient xylose-fermenting recombinant strains of S.... (More)
- Metabolic engineering of Saccharomyces cerevisiae for ethanolic fermentation of xylose is summarized with emphasis on progress made during the last decade. Advances in xylose transport, initial xylose metabolism, selection of host strains, transformation and classical breeding techniques applied to industrial polyploid strains as well as modeling of xylose metabolism are discussed. The production and composition of the substrates--lignocellulosic hydrolysates--is briefly summarized. In a future outlook iterative strategies involving the techniques of classical breeding, quantitative physiology, proteomics, DNA micro arrays, and genetic engineering are proposed for the development of efficient xylose-fermenting recombinant strains of S. cerevisiae. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/107083
- author
- Hahn-Hägerdal, Bärbel LU ; Wahlbom, Fredrik LU ; Gárdonyi, Márk LU ; van Zyl, W H ; Cordero Otero, R R and Jönsson, L J
- organization
- publishing date
- 2001
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Hexoses : metabolism, Xylulose : metabolism, Xylose : metabolism, Support, Non-U.S. Gov't, Saccharomyces cerevisiae : metabolism, Biological Transport, Fermentation, Pentoses : metabolism
- in
- Advances in Biochemical Engineering, Biotechnology
- volume
- 73
- pages
- 53 - 84
- publisher
- Springer
- external identifiers
-
- scopus:0035233593
- ISSN
- 0724-6145
- language
- English
- LU publication?
- yes
- id
- 994c0d35-ad02-4f07-ab79-1d236139d655 (old id 107083)
- alternative location
- http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11816812&dopt=Abstract
- date added to LUP
- 2016-04-01 16:07:52
- date last changed
- 2022-03-14 22:19:50
@article{994c0d35-ad02-4f07-ab79-1d236139d655, abstract = {{Metabolic engineering of Saccharomyces cerevisiae for ethanolic fermentation of xylose is summarized with emphasis on progress made during the last decade. Advances in xylose transport, initial xylose metabolism, selection of host strains, transformation and classical breeding techniques applied to industrial polyploid strains as well as modeling of xylose metabolism are discussed. The production and composition of the substrates--lignocellulosic hydrolysates--is briefly summarized. In a future outlook iterative strategies involving the techniques of classical breeding, quantitative physiology, proteomics, DNA micro arrays, and genetic engineering are proposed for the development of efficient xylose-fermenting recombinant strains of S. cerevisiae.}}, author = {{Hahn-Hägerdal, Bärbel and Wahlbom, Fredrik and Gárdonyi, Márk and van Zyl, W H and Cordero Otero, R R and Jönsson, L J}}, issn = {{0724-6145}}, keywords = {{Hexoses : metabolism; Xylulose : metabolism; Xylose : metabolism; Support; Non-U.S. Gov't; Saccharomyces cerevisiae : metabolism; Biological Transport; Fermentation; Pentoses : metabolism}}, language = {{eng}}, pages = {{53--84}}, publisher = {{Springer}}, series = {{Advances in Biochemical Engineering, Biotechnology}}, title = {{Metabolic engineering of Saccharomyces cerevisiae for xylose utilization.}}, url = {{http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11816812&dopt=Abstract}}, volume = {{73}}, year = {{2001}}, }