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Risk of recurrent laryngeal nerve palsy in patients undergoing thyroidectomy with and without intraoperative nerve monitoring

Bergenfelz, A. LU ; SALEM, FARHADULLAH LU ; Jacobsson, H.; Nordenström, E. LU ; Almquist, M. LU and , (2016) In British Journal of Surgery 103(13). p.1828-1838
Abstract

Background: Vocal cord palsy occurs in 3-5 per cent of patients after thyroidectomy. To reduce this complication, intraoperative nerve monitoring (IONM) has been introduced, although its use remains controversial. This study investigated the risk of postoperative vocal cord palsy with and without the use of intermittent IONM. Methods: Patients registered in the Scandinavian Quality Register for Thyroid, Parathyroid and Adrenal Surgery, 2009-2013, were included. Early palsy of the recurrent laryngeal nerve was diagnosed within 6weeks after surgery. Permanent palsy was defined as that persisting after 6months. Univariable and multivariable logistic regression analyses were used to examine risk factors for vocal cord palsy. Results: The... (More)

Background: Vocal cord palsy occurs in 3-5 per cent of patients after thyroidectomy. To reduce this complication, intraoperative nerve monitoring (IONM) has been introduced, although its use remains controversial. This study investigated the risk of postoperative vocal cord palsy with and without the use of intermittent IONM. Methods: Patients registered in the Scandinavian Quality Register for Thyroid, Parathyroid and Adrenal Surgery, 2009-2013, were included. Early palsy of the recurrent laryngeal nerve was diagnosed within 6weeks after surgery. Permanent palsy was defined as that persisting after 6months. Univariable and multivariable logistic regression analyses were used to examine risk factors for vocal cord palsy. Results: The cohort consisted of 5252 patients undergoing thyroidectomy. IONM was used in 3277 operations (62·4 per cent); routine postoperative laryngoscopy was performed in 1757 patients (33·5 per cent). Early vocal cord palsy occurred in 217 patients (4·1 per cent), of which three were bilateral, all in the group without IONM. Permanent vocal cord palsy occurred in 62 patients (1·2 per cent). In the multivariable analysis of 1757 patients who had postoperative laryngoscopy, the use of IONM was not associated with a decreased risk of early vocal cord palsy (odds ratio (OR) 0·67, 95 per cent c.i. 0·44 to 1·01), but decreased the risk of permanent vocal cord palsy (OR 0·43, 0·19 to 0·93). Conclusion: IONM reduced the risk of permanent vocal cord palsy. No bilateral recurrent laryngeal nerve injury occurred following IONM.

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author
organization
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type
Contribution to journal
publication status
published
subject
in
British Journal of Surgery
volume
103
issue
13
pages
1828 - 1838
publisher
John Wiley & Sons
external identifiers
  • scopus:84982276416
ISSN
0007-1323
DOI
10.1002/bjs.10276
language
English
LU publication?
yes
id
99557124-a366-45f1-a7b4-745166a964c0
date added to LUP
2016-10-10 10:31:14
date last changed
2017-06-11 05:09:07
@article{99557124-a366-45f1-a7b4-745166a964c0,
  abstract     = {<p>Background: Vocal cord palsy occurs in 3-5 per cent of patients after thyroidectomy. To reduce this complication, intraoperative nerve monitoring (IONM) has been introduced, although its use remains controversial. This study investigated the risk of postoperative vocal cord palsy with and without the use of intermittent IONM. Methods: Patients registered in the Scandinavian Quality Register for Thyroid, Parathyroid and Adrenal Surgery, 2009-2013, were included. Early palsy of the recurrent laryngeal nerve was diagnosed within 6weeks after surgery. Permanent palsy was defined as that persisting after 6months. Univariable and multivariable logistic regression analyses were used to examine risk factors for vocal cord palsy. Results: The cohort consisted of 5252 patients undergoing thyroidectomy. IONM was used in 3277 operations (62·4 per cent); routine postoperative laryngoscopy was performed in 1757 patients (33·5 per cent). Early vocal cord palsy occurred in 217 patients (4·1 per cent), of which three were bilateral, all in the group without IONM. Permanent vocal cord palsy occurred in 62 patients (1·2 per cent). In the multivariable analysis of 1757 patients who had postoperative laryngoscopy, the use of IONM was not associated with a decreased risk of early vocal cord palsy (odds ratio (OR) 0·67, 95 per cent c.i. 0·44 to 1·01), but decreased the risk of permanent vocal cord palsy (OR 0·43, 0·19 to 0·93). Conclusion: IONM reduced the risk of permanent vocal cord palsy. No bilateral recurrent laryngeal nerve injury occurred following IONM.</p>},
  author       = {Bergenfelz, A. and SALEM, FARHADULLAH and Jacobsson, H. and Nordenström, E. and Almquist, M. and , },
  issn         = {0007-1323},
  language     = {eng},
  number       = {13},
  pages        = {1828--1838},
  publisher    = {John Wiley & Sons},
  series       = {British Journal of Surgery},
  title        = {Risk of recurrent laryngeal nerve palsy in patients undergoing thyroidectomy with and without intraoperative nerve monitoring},
  url          = {http://dx.doi.org/10.1002/bjs.10276},
  volume       = {103},
  year         = {2016},
}