Management and outcomes following emergency surgery for traumatic brain injury – A multi-centre, international, prospective cohort study (the Global Neurotrauma Outcomes Study)
(2020) In International Journal of Surgery Protocols 20. p.1-7- Abstract
Introduction: Traumatic brain injury (TBI) accounts for a significant amount of death and disability worldwide and the majority of this burden affects individuals in low-and-middle income countries. Despite this, considerable geographical differences have been reported in the care of TBI patients. On this background, we aim to provide a comprehensive international picture of the epidemiological characteristics, management and outcomes of patients undergoing emergency surgery for traumatic brain injury (TBI) worldwide. Methods and analysis: The Global Neurotrauma Outcomes Study (GNOS) is a multi-centre, international, prospective observational cohort study. Any unit performing emergency surgery for TBI worldwide will be eligible to... (More)
Introduction: Traumatic brain injury (TBI) accounts for a significant amount of death and disability worldwide and the majority of this burden affects individuals in low-and-middle income countries. Despite this, considerable geographical differences have been reported in the care of TBI patients. On this background, we aim to provide a comprehensive international picture of the epidemiological characteristics, management and outcomes of patients undergoing emergency surgery for traumatic brain injury (TBI) worldwide. Methods and analysis: The Global Neurotrauma Outcomes Study (GNOS) is a multi-centre, international, prospective observational cohort study. Any unit performing emergency surgery for TBI worldwide will be eligible to participate. All TBI patients who receive emergency surgery in any given consecutive 30-day period beginning between 1st of November 2018 and 31st of December 2019 in a given participating unit will be included. Data will be collected via a secure online platform in anonymised form. The primary outcome measures for the study will be 14-day mortality (or survival to hospital discharge, whichever comes first). Final day of data collection for the primary outcome measure is February 13th. Secondary outcome measures include return to theatre and surgical site infection. Ethics and dissemination: This project will not affect clinical practice and has been classified as clinical audit following research ethics review. Access to source data will be made available to collaborators through national or international anonymised datasets on request and after review of the scientific validity of the proposed analysis by the central study team.
(Less)
- author
- Clark, David
; Joannides, Alexis
; Ibrahim Abdallah, Omar
; Olufemi Adeleye, Amos
; Hafid Bajamal, Abdul
; Bashford, Tom
; Bhebhe, Arnold
; Biluts, Hagos
; Budohoska, Natalia
; Budohoski, Karol
; Cherian, Iype
; Marklund, Niklas
LU
; Fernandez Mendez, Rocio
; Figaji, Tony
; Kumar Gupta, Deepak
; Iaccarino, Corrado
; Ilunga, Ali
; Joseph, Mathew
; Khan, Tariq
; Laeke, Tsegazeab
; Waran, Vicknes
; Park, Kee
; Rosseau, Gail
; Rubiano, Andres
; Saleh, Youssuf
; Shabani, Hamisi K.
; Smith, Brandon
; Sichizya, Kachinga
; Tewari, Manoj
; Tirsit, Abenezer
; Thu, Myat
; Tripathi, Manjul
; Trivedi, Rikin
; Villar, Sofia
; Devi Bhagavatula, Indira
; Servadei, Franco
; Menon, David
; Kolias, Angelos
and Hutchinson, Peter
(Less) - organization
- publishing date
- 2020
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- Brain injuries, Epidemiology, Global health, Injuries, Neurosurgery, Traumatic
- in
- International Journal of Surgery Protocols
- volume
- 20
- pages
- 7 pages
- publisher
- Elsevier
- external identifiers
-
- pmid:32211566
- scopus:85081982002
- ISSN
- 2468-3574
- DOI
- 10.1016/j.isjp.2020.02.001
- language
- English
- LU publication?
- yes
- id
- 99a29476-4e7f-4c6c-b2ae-41bc26413c14
- date added to LUP
- 2020-04-09 11:46:09
- date last changed
- 2024-05-29 10:54:06
@article{99a29476-4e7f-4c6c-b2ae-41bc26413c14,
abstract = {{<p>Introduction: Traumatic brain injury (TBI) accounts for a significant amount of death and disability worldwide and the majority of this burden affects individuals in low-and-middle income countries. Despite this, considerable geographical differences have been reported in the care of TBI patients. On this background, we aim to provide a comprehensive international picture of the epidemiological characteristics, management and outcomes of patients undergoing emergency surgery for traumatic brain injury (TBI) worldwide. Methods and analysis: The Global Neurotrauma Outcomes Study (GNOS) is a multi-centre, international, prospective observational cohort study. Any unit performing emergency surgery for TBI worldwide will be eligible to participate. All TBI patients who receive emergency surgery in any given consecutive 30-day period beginning between 1st of November 2018 and 31st of December 2019 in a given participating unit will be included. Data will be collected via a secure online platform in anonymised form. The primary outcome measures for the study will be 14-day mortality (or survival to hospital discharge, whichever comes first). Final day of data collection for the primary outcome measure is February 13th. Secondary outcome measures include return to theatre and surgical site infection. Ethics and dissemination: This project will not affect clinical practice and has been classified as clinical audit following research ethics review. Access to source data will be made available to collaborators through national or international anonymised datasets on request and after review of the scientific validity of the proposed analysis by the central study team.</p>}},
author = {{Clark, David and Joannides, Alexis and Ibrahim Abdallah, Omar and Olufemi Adeleye, Amos and Hafid Bajamal, Abdul and Bashford, Tom and Bhebhe, Arnold and Biluts, Hagos and Budohoska, Natalia and Budohoski, Karol and Cherian, Iype and Marklund, Niklas and Fernandez Mendez, Rocio and Figaji, Tony and Kumar Gupta, Deepak and Iaccarino, Corrado and Ilunga, Ali and Joseph, Mathew and Khan, Tariq and Laeke, Tsegazeab and Waran, Vicknes and Park, Kee and Rosseau, Gail and Rubiano, Andres and Saleh, Youssuf and Shabani, Hamisi K. and Smith, Brandon and Sichizya, Kachinga and Tewari, Manoj and Tirsit, Abenezer and Thu, Myat and Tripathi, Manjul and Trivedi, Rikin and Villar, Sofia and Devi Bhagavatula, Indira and Servadei, Franco and Menon, David and Kolias, Angelos and Hutchinson, Peter}},
issn = {{2468-3574}},
keywords = {{Brain injuries; Epidemiology; Global health; Injuries; Neurosurgery; Traumatic}},
language = {{eng}},
pages = {{1--7}},
publisher = {{Elsevier}},
series = {{International Journal of Surgery Protocols}},
title = {{Management and outcomes following emergency surgery for traumatic brain injury – A multi-centre, international, prospective cohort study (the Global Neurotrauma Outcomes Study)}},
url = {{http://dx.doi.org/10.1016/j.isjp.2020.02.001}},
doi = {{10.1016/j.isjp.2020.02.001}},
volume = {{20}},
year = {{2020}},
}