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Costs of treating primary open-angle glaucoma and ocular hypertension : A retrospective, observational two-year chart review of newly diagnosed patients in Sweden and the United States

Kobelt-Nguyen, Gisela; Gerdtham, Ulf G. LU and Alm, Albert (1998) In Journal of Glaucoma 7(2). p.95-104
Abstract

Purpose: The objective of this study was to investigate what treatment strategies prevail in different countries for patients newly diagnosed with primary open-angle glaucoma (POAG) or ocular hypertension (OH) only and initiated on treatment with beta-blockers, and to estimate the total direct cost of treatment for two years. In addition, differences in costs between and within the countries and the determinants of variations in costs across patients were examined. Materials and Methods: The authors performed a retrospective medical record analysis in several academic and office-based study centers in Sweden and the United States. Standard costs for each resource item were determined and applied to all centers within the country.... (More)

Purpose: The objective of this study was to investigate what treatment strategies prevail in different countries for patients newly diagnosed with primary open-angle glaucoma (POAG) or ocular hypertension (OH) only and initiated on treatment with beta-blockers, and to estimate the total direct cost of treatment for two years. In addition, differences in costs between and within the countries and the determinants of variations in costs across patients were examined. Materials and Methods: The authors performed a retrospective medical record analysis in several academic and office-based study centers in Sweden and the United States. Standard costs for each resource item were determined and applied to all centers within the country. Differences in treatment costs within the countries are thus the effect of differences in treatment strategies, not of differences in prices. Results: There was considerable variation between the centers of each country. Sweden had a higher number of surgical interventions, which may be explained by the fact that the Swedish cohort had a higher mean intraocular pressure (IOP) at baseline and a higher proportion of patients with definite POAG and exfoliation glaucoma. However, in both countries the mean IOP at study end was approximately 18 mm HE. Total direct costs for two years were 15,119 SEK (US$ 2160; $ 1US = 7 SEK) and $ 2109, respectively. In a multiple regression analysis, the estimated effects of baseline IOP and of IOP change after treatment initiation on treatment costs were positively and negatively significant, respectively, in both countries. Conclusion: Despite differences in baseline diagnosis and in treatment strategies, mean IOP was decreased to 18 mm Hg in both countries. Baseline IOP was positively correlated with treatment costs, while the initial IOP-lowering effect of treatment was negatively correlated with two-year costs.

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author
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Costs, Intraocular pressure, Ocular hypertension, Primary open-angle glaucoma, Treatment strategies
in
Journal of Glaucoma
volume
7
issue
2
pages
10 pages
publisher
Raven Press
external identifiers
  • scopus:0031968095
ISSN
1057-0829
language
English
LU publication?
no
id
99a29ad4-cd1f-43f1-9a01-22e0a7585827
date added to LUP
2018-10-09 12:30:29
date last changed
2019-01-06 14:08:57
@article{99a29ad4-cd1f-43f1-9a01-22e0a7585827,
  abstract     = {<p>Purpose: The objective of this study was to investigate what treatment strategies prevail in different countries for patients newly diagnosed with primary open-angle glaucoma (POAG) or ocular hypertension (OH) only and initiated on treatment with beta-blockers, and to estimate the total direct cost of treatment for two years. In addition, differences in costs between and within the countries and the determinants of variations in costs across patients were examined. Materials and Methods: The authors performed a retrospective medical record analysis in several academic and office-based study centers in Sweden and the United States. Standard costs for each resource item were determined and applied to all centers within the country. Differences in treatment costs within the countries are thus the effect of differences in treatment strategies, not of differences in prices. Results: There was considerable variation between the centers of each country. Sweden had a higher number of surgical interventions, which may be explained by the fact that the Swedish cohort had a higher mean intraocular pressure (IOP) at baseline and a higher proportion of patients with definite POAG and exfoliation glaucoma. However, in both countries the mean IOP at study end was approximately 18 mm HE. Total direct costs for two years were 15,119 SEK (US$ 2160; $ 1US = 7 SEK) and $ 2109, respectively. In a multiple regression analysis, the estimated effects of baseline IOP and of IOP change after treatment initiation on treatment costs were positively and negatively significant, respectively, in both countries. Conclusion: Despite differences in baseline diagnosis and in treatment strategies, mean IOP was decreased to 18 mm Hg in both countries. Baseline IOP was positively correlated with treatment costs, while the initial IOP-lowering effect of treatment was negatively correlated with two-year costs.</p>},
  author       = {Kobelt-Nguyen, Gisela and Gerdtham, Ulf G. and Alm, Albert},
  issn         = {1057-0829},
  keyword      = {Costs,Intraocular pressure,Ocular hypertension,Primary open-angle glaucoma,Treatment strategies},
  language     = {eng},
  month        = {04},
  number       = {2},
  pages        = {95--104},
  publisher    = {Raven Press},
  series       = {Journal of Glaucoma},
  title        = {Costs of treating primary open-angle glaucoma and ocular hypertension : A retrospective, observational two-year chart review of newly diagnosed patients in Sweden and the United States},
  volume       = {7},
  year         = {1998},
}