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Incidence of Primary Cancers and Intracranial Tumour Recurrences in Growth Hormone-Treated and Untreated Adult Hypopituitary Patients: Analyses from Hypopituitary Control and Complications Study

Child, Christopher J ; Conroy, Daniel ; Zimmermann, Alan G ; Woodmansee, Whitney ; Erfurth, Eva Marie LU and Robison, Leslie (2015) In European Journal of Endocrinology 172(6). p.779-790
Abstract
Speculation remains that growth hormone (GH) treatment is associated with increased neoplasia risk. Studies in GH-treated childhood cancer survivors suggested higher rates of second neoplasms, while cancer risk data for GH-treated and untreated hypopituitary adults have been variable. We present primary cancer risk data from the Hypopituitary Control and Complications Study (HypoCCS) with a focus on specific cancers, and assessment of recurrence rates for pituitary adenoma (PA) and craniopharyngioma (CP).
Please use this url to cite or link to this publication:
author
; ; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
European Journal of Endocrinology
volume
172
issue
6
pages
779 - 790
publisher
Society of the European Journal of Endocrinology
external identifiers
  • pmid:25810462
  • wos:000357212600022
  • scopus:84930607776
  • pmid:25810462
ISSN
1479-683X
DOI
10.1530/EJE-14-1123
language
English
LU publication?
yes
id
9a2dbbb7-cbd7-41e6-9d27-a9ff106a54bf (old id 5257637)
alternative location
http://www.ncbi.nlm.nih.gov/pubmed/25810462?dopt=Abstract
date added to LUP
2016-04-01 10:12:07
date last changed
2024-01-06 10:26:15
@article{9a2dbbb7-cbd7-41e6-9d27-a9ff106a54bf,
  abstract     = {{Speculation remains that growth hormone (GH) treatment is associated with increased neoplasia risk. Studies in GH-treated childhood cancer survivors suggested higher rates of second neoplasms, while cancer risk data for GH-treated and untreated hypopituitary adults have been variable. We present primary cancer risk data from the Hypopituitary Control and Complications Study (HypoCCS) with a focus on specific cancers, and assessment of recurrence rates for pituitary adenoma (PA) and craniopharyngioma (CP).}},
  author       = {{Child, Christopher J and Conroy, Daniel and Zimmermann, Alan G and Woodmansee, Whitney and Erfurth, Eva Marie and Robison, Leslie}},
  issn         = {{1479-683X}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{779--790}},
  publisher    = {{Society of the European Journal of Endocrinology}},
  series       = {{European Journal of Endocrinology}},
  title        = {{Incidence of Primary Cancers and Intracranial Tumour Recurrences in Growth Hormone-Treated and Untreated Adult Hypopituitary Patients: Analyses from Hypopituitary Control and Complications Study}},
  url          = {{http://dx.doi.org/10.1530/EJE-14-1123}},
  doi          = {{10.1530/EJE-14-1123}},
  volume       = {{172}},
  year         = {{2015}},
}