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Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy)

Thim, Troels ; Götberg, Matthias LU ; Fröbert, Ole ; Nijveldt, Robin ; van Royen, Niels ; Baptista, Sergio Bravo ; Koul, Sasha LU ; Kellerth, Thomas ; Bøtker, Hans Erik and Terkelsen, Christian Juhl , et al. (2020) In BMC Research Notes 13(1).
Abstract

OBJECTIVE: To evaluate agreement between instantaneous wave free ratio (iFR) and fractional flow reserve (FFR) for the functional assessment of nonculprit coronary stenoses at staged follow-up after ST-segment elevation myocardial infarction (STEMI). RESULTS: We measured iFR and FFR at staged follow-up in 112 STEMI patients with 146 nonculprit stenoses. Median interval between STEMI and follow-up was 16 (interquartile range 5-32) days. Agreement between iFR and FFR was 77% < 5 days after STEMI and 86% after ≥ 5 days (p = 0.19). Among cases with disagreement, the proportion of cases with hemodynamically significant iFR and non-significant FFR were different when assessed < 5 days (5 in 8, 63%) versus ≥ 5 days (3 in 15, 20%) after... (More)

OBJECTIVE: To evaluate agreement between instantaneous wave free ratio (iFR) and fractional flow reserve (FFR) for the functional assessment of nonculprit coronary stenoses at staged follow-up after ST-segment elevation myocardial infarction (STEMI). RESULTS: We measured iFR and FFR at staged follow-up in 112 STEMI patients with 146 nonculprit stenoses. Median interval between STEMI and follow-up was 16 (interquartile range 5-32) days. Agreement between iFR and FFR was 77% < 5 days after STEMI and 86% after ≥ 5 days (p = 0.19). Among cases with disagreement, the proportion of cases with hemodynamically significant iFR and non-significant FFR were different when assessed < 5 days (5 in 8, 63%) versus ≥ 5 days (3 in 15, 20%) after STEMI (p = 0.04). Overall classification agreement between iFR and FFR was comparable to that observed in stable patients. Time interval between STEMI and follow-up evaluation may impact agreement between iFR and FFR.

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publishing date
type
Contribution to journal
publication status
published
subject
keywords
FFR, Fractional flow reserve, iFR, Instantaneous wave-free ration, Nonculprit stenosis, ST-segment elevation myocardial infarction
in
BMC Research Notes
volume
13
issue
1
article number
410
publisher
BioMed Central (BMC)
external identifiers
  • scopus:85090182231
  • pmid:32873327
ISSN
1756-0500
DOI
10.1186/s13104-020-05252-6
language
English
LU publication?
no
id
9bcd32c2-ee03-4370-958b-38c131ac4852
date added to LUP
2020-09-25 11:05:11
date last changed
2023-11-06 00:20:23
@article{9bcd32c2-ee03-4370-958b-38c131ac4852,
  abstract     = {{<p>OBJECTIVE: To evaluate agreement between instantaneous wave free ratio (iFR) and fractional flow reserve (FFR) for the functional assessment of nonculprit coronary stenoses at staged follow-up after ST-segment elevation myocardial infarction (STEMI). RESULTS: We measured iFR and FFR at staged follow-up in 112 STEMI patients with 146 nonculprit stenoses. Median interval between STEMI and follow-up was 16 (interquartile range 5-32) days. Agreement between iFR and FFR was 77% &lt; 5 days after STEMI and 86% after ≥ 5 days (p = 0.19). Among cases with disagreement, the proportion of cases with hemodynamically significant iFR and non-significant FFR were different when assessed &lt; 5 days (5 in 8, 63%) versus ≥ 5 days (3 in 15, 20%) after STEMI (p = 0.04). Overall classification agreement between iFR and FFR was comparable to that observed in stable patients. Time interval between STEMI and follow-up evaluation may impact agreement between iFR and FFR.</p>}},
  author       = {{Thim, Troels and Götberg, Matthias and Fröbert, Ole and Nijveldt, Robin and van Royen, Niels and Baptista, Sergio Bravo and Koul, Sasha and Kellerth, Thomas and Bøtker, Hans Erik and Terkelsen, Christian Juhl and Christiansen, Evald Høj and Jakobsen, Lars and Kristensen, Steen Dalby and Maeng, Michael}},
  issn         = {{1756-0500}},
  keywords     = {{FFR; Fractional flow reserve; iFR; Instantaneous wave-free ration; Nonculprit stenosis; ST-segment elevation myocardial infarction}},
  language     = {{eng}},
  number       = {{1}},
  publisher    = {{BioMed Central (BMC)}},
  series       = {{BMC Research Notes}},
  title        = {{Agreement between nonculprit stenosis follow-up iFR and FFR after STEMI (iSTEMI substudy)}},
  url          = {{http://dx.doi.org/10.1186/s13104-020-05252-6}},
  doi          = {{10.1186/s13104-020-05252-6}},
  volume       = {{13}},
  year         = {{2020}},
}