Analogues of 1D-Myo-inositol 1,2,6-trisphosphate. Preparation of carboxymethyl and 2-hydroxyethyl phosphate derivatives
(1997) In Journal of Carbohydrate Chemistry 16(1). p.109-112- Abstract
Acylation of 1D-myo-inositol 1,2,6-trisphosphate (α-trinositol) followed by alkylation of the phosphate groups with benzyl bromoacetate or 2-benzyloxyethyl iodide and deprotection provides a route to analogues with modified phosphate groups. The modifications made alter steric and ionisation properties but the possibility to participate in hydrogen bonding and ionic interaction is retained.
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- author
- Malmberg, Mats and Rehnberg, Nicola LU
- publishing date
- 1997
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Journal of Carbohydrate Chemistry
- volume
- 16
- issue
- 1
- pages
- 4 pages
- publisher
- Marcel Dekker
- external identifiers
-
- scopus:0031541164
- ISSN
- 0732-8303
- DOI
- 10.1080/07328309708006513
- language
- English
- LU publication?
- no
- id
- 9c449268-15ca-492c-9913-c71853f55e9c
- date added to LUP
- 2021-11-11 12:50:02
- date last changed
- 2022-02-02 01:16:14
@article{9c449268-15ca-492c-9913-c71853f55e9c, abstract = {{<p>Acylation of 1D-<i>myo</i>-inositol 1,2,6-trisphosphate (α-trinositol) followed by alkylation of the phosphate groups with benzyl bromoacetate or 2-benzyloxyethyl iodide and deprotection provides a route to analogues with modified phosphate groups. The modifications made alter steric and ionisation properties but the possibility to participate in hydrogen bonding and ionic interaction is retained.</p>}}, author = {{Malmberg, Mats and Rehnberg, Nicola}}, issn = {{0732-8303}}, language = {{eng}}, number = {{1}}, pages = {{109--112}}, publisher = {{Marcel Dekker}}, series = {{Journal of Carbohydrate Chemistry}}, title = {{Analogues of 1D-<i>Myo</i>-inositol 1,2,6-trisphosphate. Preparation of carboxymethyl and 2-hydroxyethyl phosphate derivatives}}, url = {{http://dx.doi.org/10.1080/07328309708006513}}, doi = {{10.1080/07328309708006513}}, volume = {{16}}, year = {{1997}}, }