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The venoms of the lesser (Echiichthys vipera) and greater (Trachinus draco) weever fish– A review

Gorman, Lucy M. ; Judge, Sarah J. ; Fezai, Myriam LU ; Jemaà, Mohamed LU ; Harris, John B. and Caldwell, Gary S. (2020) In Toxicon: X 6.
Abstract

In comparison with other animal venoms, fish venoms remain relatively understudied. This is especially true for that of the lesser Echiichthys vipera and greater weever fish Trachinus draco which, apart from the isolation of their unique venom cytolysins, trachinine and dracotoxin, respectively, remain relatively uncharacterised. Envenomation reports mainly include mild symptoms consisting of nociception and inflammation. However, like most fish venoms, if the venom becomes systemic it causes cardiorespiratory and blood pressure changes. Although T. draco venom has not been studied since the 1990's, recent studies on E. vipera venom have discovered novel cytotoxic components on human cancer cells, but due to the scarcity of research on... (More)

In comparison with other animal venoms, fish venoms remain relatively understudied. This is especially true for that of the lesser Echiichthys vipera and greater weever fish Trachinus draco which, apart from the isolation of their unique venom cytolysins, trachinine and dracotoxin, respectively, remain relatively uncharacterised. Envenomation reports mainly include mild symptoms consisting of nociception and inflammation. However, like most fish venoms, if the venom becomes systemic it causes cardiorespiratory and blood pressure changes. Although T. draco venom has not been studied since the 1990's, recent studies on E. vipera venom have discovered novel cytotoxic components on human cancer cells, but due to the scarcity of research on the molecular make-up of the venom, the molecule(s) causing this cytotoxicity remains unknown. This review analyses past studies on E. vipera and T. draco venom, the methods used in the, the venom constituents characterised, the reported symptoms of envenomation and compares these findings with those from other venomous Scorpaeniformes.

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organization
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type
Contribution to journal
publication status
published
subject
keywords
Cytolytic, Dracotoxin, Echiichthys vipera, Trachinine, Trachinus draco, Weever fish venom
in
Toxicon: X
volume
6
article number
100025
external identifiers
  • scopus:85079011700
DOI
10.1016/j.toxcx.2020.100025
language
English
LU publication?
yes
id
9cdf2a64-e52b-4979-b855-061a8603c2dc
date added to LUP
2020-02-14 09:15:27
date last changed
2020-02-26 07:41:49
@article{9cdf2a64-e52b-4979-b855-061a8603c2dc,
  abstract     = {<p>In comparison with other animal venoms, fish venoms remain relatively understudied. This is especially true for that of the lesser Echiichthys vipera and greater weever fish Trachinus draco which, apart from the isolation of their unique venom cytolysins, trachinine and dracotoxin, respectively, remain relatively uncharacterised. Envenomation reports mainly include mild symptoms consisting of nociception and inflammation. However, like most fish venoms, if the venom becomes systemic it causes cardiorespiratory and blood pressure changes. Although T. draco venom has not been studied since the 1990's, recent studies on E. vipera venom have discovered novel cytotoxic components on human cancer cells, but due to the scarcity of research on the molecular make-up of the venom, the molecule(s) causing this cytotoxicity remains unknown. This review analyses past studies on E. vipera and T. draco venom, the methods used in the, the venom constituents characterised, the reported symptoms of envenomation and compares these findings with those from other venomous Scorpaeniformes.</p>},
  author       = {Gorman, Lucy M. and Judge, Sarah J. and Fezai, Myriam and Jemaà, Mohamed and Harris, John B. and Caldwell, Gary S.},
  language     = {eng},
  series       = {Toxicon: X},
  title        = {The venoms of the lesser (Echiichthys vipera) and greater (Trachinus draco) weever fish– A review},
  url          = {http://dx.doi.org/10.1016/j.toxcx.2020.100025},
  doi          = {10.1016/j.toxcx.2020.100025},
  volume       = {6},
  year         = {2020},
}