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Determination of diffusion coefficients in bovine bone by means of conductivity measurement

Lindberg, Gustav LU orcid ; Shokry, Abdallah LU ; Reheman, Wureguli LU and Svensson, Ingrid LU (2014) In International Journal of Experimental and Computational Biomechanics 2(4). p.324-342
Abstract
Measuring the diffusivity of various substances in cortical bone is in

general difficult. For instance, making use of micro computed tomography requires agents that can be separated from bone, blood and other substances that exist in cortical bone. Here a more easily accessible method is presented. A series of cortical bovine bone samples were put in a saturated solution of potassium chloride for a time period that was long enough for the samples to be regarded as saturated. The samples were removed from the solution and moulded in polyester leaving only the radial directions open. In the next step,

the bone samples were put in distilled water and the conductivity of the water was registered over time. An analytical model... (More)
Measuring the diffusivity of various substances in cortical bone is in

general difficult. For instance, making use of micro computed tomography requires agents that can be separated from bone, blood and other substances that exist in cortical bone. Here a more easily accessible method is presented. A series of cortical bovine bone samples were put in a saturated solution of potassium chloride for a time period that was long enough for the samples to be regarded as saturated. The samples were removed from the solution and moulded in polyester leaving only the radial directions open. In the next step,

the bone samples were put in distilled water and the conductivity of the water was registered over time. An analytical model fulfilling Ficks law was introduced and by means of Kalman filtering an estimation for the diffusion coefficient of potassium chloride in bovine bone is presented. (Less)
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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
experimental biomechanics, transient solution, Kalman filter, Fourier series, Fick’s law, conductivity measurement, diffusion experiment, diffusion in bovine bone, bone material constants
in
International Journal of Experimental and Computational Biomechanics
volume
2
issue
4
pages
18 pages
publisher
Inderscience Publishers
ISSN
1755-8735
DOI
10.1504/IJECB.2014.066086
language
English
LU publication?
yes
id
a052ef4b-d531-46f8-9f6b-f8386ca991ee (old id 4856483)
date added to LUP
2016-04-01 10:51:11
date last changed
2019-12-17 13:16:04
@article{a052ef4b-d531-46f8-9f6b-f8386ca991ee,
  abstract     = {{Measuring the diffusivity of various substances in cortical bone is in<br/><br>
general difficult. For instance, making use of micro computed tomography requires agents that can be separated from bone, blood and other substances that exist in cortical bone. Here a more easily accessible method is presented. A series of cortical bovine bone samples were put in a saturated solution of potassium chloride for a time period that was long enough for the samples to be regarded as saturated. The samples were removed from the solution and moulded in polyester leaving only the radial directions open. In the next step,<br/><br>
the bone samples were put in distilled water and the conductivity of the water was registered over time. An analytical model fulfilling Ficks law was introduced and by means of Kalman filtering an estimation for the diffusion coefficient of potassium chloride in bovine bone is presented.}},
  author       = {{Lindberg, Gustav and Shokry, Abdallah and Reheman, Wureguli and Svensson, Ingrid}},
  issn         = {{1755-8735}},
  keywords     = {{experimental biomechanics; transient solution; Kalman filter; Fourier series; Fick’s law; conductivity measurement; diffusion experiment; diffusion in bovine bone; bone material constants}},
  language     = {{eng}},
  number       = {{4}},
  pages        = {{324--342}},
  publisher    = {{Inderscience Publishers}},
  series       = {{International Journal of Experimental and Computational Biomechanics}},
  title        = {{Determination of diffusion coefficients in bovine bone by means of conductivity measurement}},
  url          = {{http://dx.doi.org/10.1504/IJECB.2014.066086}},
  doi          = {{10.1504/IJECB.2014.066086}},
  volume       = {{2}},
  year         = {{2014}},
}