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Correction for scatter and septal penetration using convolution subtraction methods and model-based compensation in I-123 brain SPECT imaging - a Monte Carlo study

Larsson, Anne; Ljungberg, Michael LU ; Mo, Susanna Jakobson; Riklund, Katrine and Johansson, Lennart (2006) In Physics in Medicine and Biology 51(22). p.5753-5767
Abstract
Scatter and septal penetration deteriorate contrast and quantitative accuracy in single photon emission computed tomography ( SPECT). In this study four different correction techniques for scatter and septal penetration are evaluated for I-123 brain SPECT. One of the methods is a form of model-based compensation which uses the effective source scatter estimation ( ESSE) for modelling scatter, and collimator-detector response ( CDR) including both geometric and penetration components. The other methods, which operate on the 2D projection images, are convolution scatter subtraction ( CSS) and two versions of transmission dependent convolution subtraction ( TDCS), one of them proposed by us. This method uses CSS for correction for septal... (More)
Scatter and septal penetration deteriorate contrast and quantitative accuracy in single photon emission computed tomography ( SPECT). In this study four different correction techniques for scatter and septal penetration are evaluated for I-123 brain SPECT. One of the methods is a form of model-based compensation which uses the effective source scatter estimation ( ESSE) for modelling scatter, and collimator-detector response ( CDR) including both geometric and penetration components. The other methods, which operate on the 2D projection images, are convolution scatter subtraction ( CSS) and two versions of transmission dependent convolution subtraction ( TDCS), one of them proposed by us. This method uses CSS for correction for septal penetration, with a separate kernel, and TDCS for scatter correction. The corrections are evaluated for a dopamine transporter ( DAT) study and a study of the regional cerebral blood flow ( rCBF), performed with I-123. The images are produced using a recently developed Monte Carlo collimator routine added to the program SIMIND which can include interactions in the collimator. The results show that the method included in the iterative reconstruction is preferable to the other methods and that the new TDCS version gives better results compared with the other 2D methods. (Less)
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type
Contribution to journal
publication status
published
subject
in
Physics in Medicine and Biology
volume
51
issue
22
pages
5753 - 5767
publisher
IOP Publishing
external identifiers
  • wos:000242615500003
  • scopus:33846857552
ISSN
1361-6560
DOI
10.1088/0031-9155/51/22/003
language
English
LU publication?
yes
id
a0c7f8fd-1ac4-4079-ba8a-8b929a825b4d (old id 683567)
date added to LUP
2007-12-20 10:22:54
date last changed
2019-02-20 04:14:18
@article{a0c7f8fd-1ac4-4079-ba8a-8b929a825b4d,
  abstract     = {Scatter and septal penetration deteriorate contrast and quantitative accuracy in single photon emission computed tomography ( SPECT). In this study four different correction techniques for scatter and septal penetration are evaluated for I-123 brain SPECT. One of the methods is a form of model-based compensation which uses the effective source scatter estimation ( ESSE) for modelling scatter, and collimator-detector response ( CDR) including both geometric and penetration components. The other methods, which operate on the 2D projection images, are convolution scatter subtraction ( CSS) and two versions of transmission dependent convolution subtraction ( TDCS), one of them proposed by us. This method uses CSS for correction for septal penetration, with a separate kernel, and TDCS for scatter correction. The corrections are evaluated for a dopamine transporter ( DAT) study and a study of the regional cerebral blood flow ( rCBF), performed with I-123. The images are produced using a recently developed Monte Carlo collimator routine added to the program SIMIND which can include interactions in the collimator. The results show that the method included in the iterative reconstruction is preferable to the other methods and that the new TDCS version gives better results compared with the other 2D methods.},
  author       = {Larsson, Anne and Ljungberg, Michael and Mo, Susanna Jakobson and Riklund, Katrine and Johansson, Lennart},
  issn         = {1361-6560},
  language     = {eng},
  number       = {22},
  pages        = {5753--5767},
  publisher    = {IOP Publishing},
  series       = {Physics in Medicine and Biology},
  title        = {Correction for scatter and septal penetration using convolution subtraction methods and model-based compensation in I-123 brain SPECT imaging - a Monte Carlo study},
  url          = {http://dx.doi.org/10.1088/0031-9155/51/22/003},
  volume       = {51},
  year         = {2006},
}