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Ant13 Encodes Regulatory Factor WD40 Controlling Anthocyanin and Proanthocyanidin Synthesis in Barley (Hordeum vulgare L.)

Shoeva, Olesya Yu ; Mukhanova, Marina A. ; Zakhrabekova, Shakhira LU and Hansson, Mats LU (2023) In Journal of Agricultural and Food Chemistry 71(18). p.6967-6977
Abstract

Flavonoid compounds like anthocyanins and proanthocyanidins are important plant secondary metabolites having wide biological activities for humans. In this study, the molecular function of the Ant13 locus, which is one of the key loci governing flavonoid synthesis in barley, was determined. It was found that Ant13 encodes a WD40-type regulatory protein, which is required for transcriptional activation of a set of structural genes encoding enzymes of flavonoid biosynthesis at the leaf sheath base (colored by anthocyanins) and in grains (which accumulate proanthocyanidins). Besides its role in flavonoid biosynthesis, pleiotropic effects of this gene in plant growth were revealed. The mutants deficient in the Ant13 locus showed similar... (More)

Flavonoid compounds like anthocyanins and proanthocyanidins are important plant secondary metabolites having wide biological activities for humans. In this study, the molecular function of the Ant13 locus, which is one of the key loci governing flavonoid synthesis in barley, was determined. It was found that Ant13 encodes a WD40-type regulatory protein, which is required for transcriptional activation of a set of structural genes encoding enzymes of flavonoid biosynthesis at the leaf sheath base (colored by anthocyanins) and in grains (which accumulate proanthocyanidins). Besides its role in flavonoid biosynthesis, pleiotropic effects of this gene in plant growth were revealed. The mutants deficient in the Ant13 locus showed similar germination rates but a decreased rate of root and shoot growth and yield-related parameters in comparison to the parental cultivars. This is the seventh Ant locus (among 30) for which molecular functions in flavonoid biosynthesis regulation have been determined.

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author
; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
anthocyanin-less, condensed tannin, flavonoid, haze, malt, regulatory gene
in
Journal of Agricultural and Food Chemistry
volume
71
issue
18
pages
11 pages
publisher
The American Chemical Society (ACS)
external identifiers
  • pmid:37104658
  • scopus:85156274033
ISSN
0021-8561
DOI
10.1021/acs.jafc.2c09051
language
English
LU publication?
yes
id
a1d5bacf-7b94-45bf-8f87-54b82ddad742
date added to LUP
2023-08-16 14:07:22
date last changed
2024-04-20 01:48:17
@article{a1d5bacf-7b94-45bf-8f87-54b82ddad742,
  abstract     = {{<p>Flavonoid compounds like anthocyanins and proanthocyanidins are important plant secondary metabolites having wide biological activities for humans. In this study, the molecular function of the Ant13 locus, which is one of the key loci governing flavonoid synthesis in barley, was determined. It was found that Ant13 encodes a WD40-type regulatory protein, which is required for transcriptional activation of a set of structural genes encoding enzymes of flavonoid biosynthesis at the leaf sheath base (colored by anthocyanins) and in grains (which accumulate proanthocyanidins). Besides its role in flavonoid biosynthesis, pleiotropic effects of this gene in plant growth were revealed. The mutants deficient in the Ant13 locus showed similar germination rates but a decreased rate of root and shoot growth and yield-related parameters in comparison to the parental cultivars. This is the seventh Ant locus (among 30) for which molecular functions in flavonoid biosynthesis regulation have been determined.</p>}},
  author       = {{Shoeva, Olesya Yu and Mukhanova, Marina A. and Zakhrabekova, Shakhira and Hansson, Mats}},
  issn         = {{0021-8561}},
  keywords     = {{anthocyanin-less; condensed tannin; flavonoid; haze; malt; regulatory gene}},
  language     = {{eng}},
  month        = {{05}},
  number       = {{18}},
  pages        = {{6967--6977}},
  publisher    = {{The American Chemical Society (ACS)}},
  series       = {{Journal of Agricultural and Food Chemistry}},
  title        = {{Ant13 Encodes Regulatory Factor WD40 Controlling Anthocyanin and Proanthocyanidin Synthesis in Barley (Hordeum vulgare L.)}},
  url          = {{http://dx.doi.org/10.1021/acs.jafc.2c09051}},
  doi          = {{10.1021/acs.jafc.2c09051}},
  volume       = {{71}},
  year         = {{2023}},
}