Ant13 Encodes Regulatory Factor WD40 Controlling Anthocyanin and Proanthocyanidin Synthesis in Barley (Hordeum vulgare L.)
(2023) In Journal of Agricultural and Food Chemistry 71(18). p.6967-6977- Abstract
Flavonoid compounds like anthocyanins and proanthocyanidins are important plant secondary metabolites having wide biological activities for humans. In this study, the molecular function of the Ant13 locus, which is one of the key loci governing flavonoid synthesis in barley, was determined. It was found that Ant13 encodes a WD40-type regulatory protein, which is required for transcriptional activation of a set of structural genes encoding enzymes of flavonoid biosynthesis at the leaf sheath base (colored by anthocyanins) and in grains (which accumulate proanthocyanidins). Besides its role in flavonoid biosynthesis, pleiotropic effects of this gene in plant growth were revealed. The mutants deficient in the Ant13 locus showed similar... (More)
Flavonoid compounds like anthocyanins and proanthocyanidins are important plant secondary metabolites having wide biological activities for humans. In this study, the molecular function of the Ant13 locus, which is one of the key loci governing flavonoid synthesis in barley, was determined. It was found that Ant13 encodes a WD40-type regulatory protein, which is required for transcriptional activation of a set of structural genes encoding enzymes of flavonoid biosynthesis at the leaf sheath base (colored by anthocyanins) and in grains (which accumulate proanthocyanidins). Besides its role in flavonoid biosynthesis, pleiotropic effects of this gene in plant growth were revealed. The mutants deficient in the Ant13 locus showed similar germination rates but a decreased rate of root and shoot growth and yield-related parameters in comparison to the parental cultivars. This is the seventh Ant locus (among 30) for which molecular functions in flavonoid biosynthesis regulation have been determined.
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- author
- Shoeva, Olesya Yu ; Mukhanova, Marina A. ; Zakhrabekova, Shakhira LU and Hansson, Mats LU
- organization
- publishing date
- 2023-05-10
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- anthocyanin-less, condensed tannin, flavonoid, haze, malt, regulatory gene
- in
- Journal of Agricultural and Food Chemistry
- volume
- 71
- issue
- 18
- pages
- 11 pages
- publisher
- The American Chemical Society (ACS)
- external identifiers
-
- pmid:37104658
- scopus:85156274033
- ISSN
- 0021-8561
- DOI
- 10.1021/acs.jafc.2c09051
- language
- English
- LU publication?
- yes
- id
- a1d5bacf-7b94-45bf-8f87-54b82ddad742
- date added to LUP
- 2023-08-16 14:07:22
- date last changed
- 2024-04-20 01:48:17
@article{a1d5bacf-7b94-45bf-8f87-54b82ddad742, abstract = {{<p>Flavonoid compounds like anthocyanins and proanthocyanidins are important plant secondary metabolites having wide biological activities for humans. In this study, the molecular function of the Ant13 locus, which is one of the key loci governing flavonoid synthesis in barley, was determined. It was found that Ant13 encodes a WD40-type regulatory protein, which is required for transcriptional activation of a set of structural genes encoding enzymes of flavonoid biosynthesis at the leaf sheath base (colored by anthocyanins) and in grains (which accumulate proanthocyanidins). Besides its role in flavonoid biosynthesis, pleiotropic effects of this gene in plant growth were revealed. The mutants deficient in the Ant13 locus showed similar germination rates but a decreased rate of root and shoot growth and yield-related parameters in comparison to the parental cultivars. This is the seventh Ant locus (among 30) for which molecular functions in flavonoid biosynthesis regulation have been determined.</p>}}, author = {{Shoeva, Olesya Yu and Mukhanova, Marina A. and Zakhrabekova, Shakhira and Hansson, Mats}}, issn = {{0021-8561}}, keywords = {{anthocyanin-less; condensed tannin; flavonoid; haze; malt; regulatory gene}}, language = {{eng}}, month = {{05}}, number = {{18}}, pages = {{6967--6977}}, publisher = {{The American Chemical Society (ACS)}}, series = {{Journal of Agricultural and Food Chemistry}}, title = {{Ant13 Encodes Regulatory Factor WD40 Controlling Anthocyanin and Proanthocyanidin Synthesis in Barley (Hordeum vulgare L.)}}, url = {{http://dx.doi.org/10.1021/acs.jafc.2c09051}}, doi = {{10.1021/acs.jafc.2c09051}}, volume = {{71}}, year = {{2023}}, }