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Sorting of Breast Cancer Cell into Different Subpopulations towards Long-Term Observation

Yilmaz, Esra LU ; Beech, Jason P. LU and Tegenfeldt, Jonas O. LU orcid (2022) 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022 In MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences p.322-323
Abstract

To study how mechanical factors influence the spread of cancer and the surrounding extracellular matrix (ECM), it is crucial that cancer cell populations be sorted without labels in relevant subpopulations with respect to mechanical properties. It is also important to confine subpopulations for long-term observation to track changes, in inherent properties of the subpopulations, and on the influence of the sorting. We have used Deterministic Lateral Displacement (DLD) for label-free continuous sorting of breast cancer cells into three different subpopulations. These were subsequently cultured for further analyses of their differences and to observe any alterations due to the sorting.

Please use this url to cite or link to this publication:
author
; and
organization
publishing date
type
Chapter in Book/Report/Conference proceeding
publication status
published
subject
keywords
Cancer metastasis, cancer subpopulations, label-free sorting, long-term observation
host publication
MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences
series title
MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences
pages
2 pages
publisher
Chemical and Biological Microsystems Society
conference name
26th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2022
conference location
Hybrid, Hangzhou, China
conference dates
2022-10-23 - 2022-10-27
external identifiers
  • scopus:85175699416
ISBN
9781733419048
language
English
LU publication?
yes
additional info
Publisher Copyright: © 2022 MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.
id
a3a77720-45a9-4b00-b32d-b82872d1611c
date added to LUP
2023-11-23 21:35:20
date last changed
2023-12-27 11:46:28
@inproceedings{a3a77720-45a9-4b00-b32d-b82872d1611c,
  abstract     = {{<p>To study how mechanical factors influence the spread of cancer and the surrounding extracellular matrix (ECM), it is crucial that cancer cell populations be sorted without labels in relevant subpopulations with respect to mechanical properties. It is also important to confine subpopulations for long-term observation to track changes, in inherent properties of the subpopulations, and on the influence of the sorting. We have used Deterministic Lateral Displacement (DLD) for label-free continuous sorting of breast cancer cells into three different subpopulations. These were subsequently cultured for further analyses of their differences and to observe any alterations due to the sorting.</p>}},
  author       = {{Yilmaz, Esra and Beech, Jason P. and Tegenfeldt, Jonas O.}},
  booktitle    = {{MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences}},
  isbn         = {{9781733419048}},
  keywords     = {{Cancer metastasis; cancer subpopulations; label-free sorting; long-term observation}},
  language     = {{eng}},
  pages        = {{322--323}},
  publisher    = {{Chemical and Biological Microsystems Society}},
  series       = {{MicroTAS 2022 - 26th International Conference on Miniaturized Systems for Chemistry and Life Sciences}},
  title        = {{Sorting of Breast Cancer Cell into Different Subpopulations towards Long-Term Observation}},
  year         = {{2022}},
}