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Synthetic polymers as solubilizing vehicles for enzymes in water-poor media

Adlercreutz, Patrick LU orcid ; Matiasson, Bo LU and Otamiri, Marina (1994) In Bioorganic and Medicinal Chemistry 2(6). p.529-533
Abstract

A recent method for exposing enzymes to organic solvents is reviewed. By complex formation between the enzyme and polymers that per se are soluble in organic solvents it is possible to disperse the enzyme in the organic medium in such a way that an optically transparent (in the visible region) solution is obtained. After reaction, the separation of the enzyme from the organic medium can be obtained simply by addition of water. The enzyme can be recovered from the water phase. Physicochemical studies have revealed that the enzyme is more stable in the complex-bound form.

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author
; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
in
Bioorganic and Medicinal Chemistry
volume
2
issue
6
pages
5 pages
publisher
Elsevier
external identifiers
  • pmid:8000875
  • scopus:0028459128
ISSN
0968-0896
DOI
10.1016/0968-0896(94)80023-5
language
English
LU publication?
yes
id
a402f296-091c-425e-98c9-1d3d9ab7beb1
date added to LUP
2019-06-22 09:12:51
date last changed
2024-01-01 12:16:42
@article{a402f296-091c-425e-98c9-1d3d9ab7beb1,
  abstract     = {{<p>A recent method for exposing enzymes to organic solvents is reviewed. By complex formation between the enzyme and polymers that per se are soluble in organic solvents it is possible to disperse the enzyme in the organic medium in such a way that an optically transparent (in the visible region) solution is obtained. After reaction, the separation of the enzyme from the organic medium can be obtained simply by addition of water. The enzyme can be recovered from the water phase. Physicochemical studies have revealed that the enzyme is more stable in the complex-bound form.</p>}},
  author       = {{Adlercreutz, Patrick and Matiasson, Bo and Otamiri, Marina}},
  issn         = {{0968-0896}},
  language     = {{eng}},
  month        = {{01}},
  number       = {{6}},
  pages        = {{529--533}},
  publisher    = {{Elsevier}},
  series       = {{Bioorganic and Medicinal Chemistry}},
  title        = {{Synthetic polymers as solubilizing vehicles for enzymes in water-poor media}},
  url          = {{http://dx.doi.org/10.1016/0968-0896(94)80023-5}},
  doi          = {{10.1016/0968-0896(94)80023-5}},
  volume       = {{2}},
  year         = {{1994}},
}