Iron Deficiency and Iron Deficiency Anemia in Chronic Disease—Common, Important, and Treatable
(2025) In Journal of Clinical Medicine 14(13).- Abstract
Iron has many important functions related to energy metabolism. However, hemoglobin synthesis is always a priority. Iron deficiency can be caused by increased loss, insufficient intake, or decreased absorption from the intestine and reduced release from depots in systemic inflammation. Anemia appears when stores are depleted or when utilization of iron from the stores is impaired. Treatment with oral iron is the first choice when the intestine is healthy, and the patient is free of inflammation. Intravenous iron is indicated when oral iron is ineffective or not tolerated and if more rapid correction is clinically indicated as in severe anemia not requiring transfusion.
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/a5e4ff36-d429-4918-baac-cd3198e7dfe5
- author
- Moum, Bjørn and Lindgren, Stefan LU
- organization
- publishing date
- 2025-07
- type
- Contribution to journal
- publication status
- published
- subject
- keywords
- chronic disease, iron deficiency, iron deficiency anemia, treatment
- in
- Journal of Clinical Medicine
- volume
- 14
- issue
- 13
- article number
- 4519
- publisher
- MDPI AG
- external identifiers
-
- scopus:105010244642
- pmid:40648893
- ISSN
- 2077-0383
- DOI
- 10.3390/jcm14134519
- language
- English
- LU publication?
- yes
- id
- a5e4ff36-d429-4918-baac-cd3198e7dfe5
- date added to LUP
- 2025-12-12 12:58:06
- date last changed
- 2025-12-13 03:00:09
@article{a5e4ff36-d429-4918-baac-cd3198e7dfe5,
abstract = {{<p>Iron has many important functions related to energy metabolism. However, hemoglobin synthesis is always a priority. Iron deficiency can be caused by increased loss, insufficient intake, or decreased absorption from the intestine and reduced release from depots in systemic inflammation. Anemia appears when stores are depleted or when utilization of iron from the stores is impaired. Treatment with oral iron is the first choice when the intestine is healthy, and the patient is free of inflammation. Intravenous iron is indicated when oral iron is ineffective or not tolerated and if more rapid correction is clinically indicated as in severe anemia not requiring transfusion.</p>}},
author = {{Moum, Bjørn and Lindgren, Stefan}},
issn = {{2077-0383}},
keywords = {{chronic disease; iron deficiency; iron deficiency anemia; treatment}},
language = {{eng}},
number = {{13}},
publisher = {{MDPI AG}},
series = {{Journal of Clinical Medicine}},
title = {{Iron Deficiency and Iron Deficiency Anemia in Chronic Disease—Common, Important, and Treatable}},
url = {{http://dx.doi.org/10.3390/jcm14134519}},
doi = {{10.3390/jcm14134519}},
volume = {{14}},
year = {{2025}},
}