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The current false lumen endograft and clinical experience for false lumen occlusion in chronic aortic dissection

Berczeli, Márton LU orcid ; Sonesson, Björn LU ; Mogensen, John ; Karelis, Angelos LU orcid and Dias, Nuno V LU orcid (2025) In The Journal of cardiovascular surgery 66(3). p.218-226
Abstract

False lumen management of chronic aortic dissections has evolved during the past decade. Thoracic endovascular aortic repair (TEVAR) continues to be the mainstay of endovascular dissection treatment and relies on the adequate sealing of the proximal entry tear. However, TEVAR alone often fails to achieve aortic remodeling due to persistent distal retrograde perfusion of the false lumen with continuous aneurysmatic degeneration. Endovascular occlusion of this retrograde false lumen flow using dedicated false lumen endografts (FLEs), has therefore gained popularity. Similar to other endografts, FLE design has evolved from extra-large vascular plug through physician modified version, to different iterations of a custom-made, self-occluding... (More)

False lumen management of chronic aortic dissections has evolved during the past decade. Thoracic endovascular aortic repair (TEVAR) continues to be the mainstay of endovascular dissection treatment and relies on the adequate sealing of the proximal entry tear. However, TEVAR alone often fails to achieve aortic remodeling due to persistent distal retrograde perfusion of the false lumen with continuous aneurysmatic degeneration. Endovascular occlusion of this retrograde false lumen flow using dedicated false lumen endografts (FLEs), has therefore gained popularity. Similar to other endografts, FLE design has evolved from extra-large vascular plug through physician modified version, to different iterations of a custom-made, self-occluding endografts. This manuscript summarizes the evolution of false lumen occluders, characteristics of the last generation of the device and currently available literature clinical experience.

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author
; ; ; and
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Humans, Aortic Dissection/surgery, Endovascular Procedures/instrumentation, Blood Vessel Prosthesis Implantation/instrumentation, Blood Vessel Prosthesis, Chronic Disease, Prosthesis Design, Treatment Outcome, Aortic Aneurysm, Thoracic/surgery, Stents
in
The Journal of cardiovascular surgery
volume
66
issue
3
pages
218 - 226
publisher
Edizioni Minerva Medica S.p.A.
external identifiers
  • scopus:105009857698
  • pmid:40406798
ISSN
0021-9509
DOI
10.23736/S0021-9509.25.13356-9
language
English
LU publication?
yes
id
a919241b-c264-4b71-961f-6d5f24a36d52
date added to LUP
2025-08-17 14:13:22
date last changed
2025-09-01 05:06:28
@article{a919241b-c264-4b71-961f-6d5f24a36d52,
  abstract     = {{<p>False lumen management of chronic aortic dissections has evolved during the past decade. Thoracic endovascular aortic repair (TEVAR) continues to be the mainstay of endovascular dissection treatment and relies on the adequate sealing of the proximal entry tear. However, TEVAR alone often fails to achieve aortic remodeling due to persistent distal retrograde perfusion of the false lumen with continuous aneurysmatic degeneration. Endovascular occlusion of this retrograde false lumen flow using dedicated false lumen endografts (FLEs), has therefore gained popularity. Similar to other endografts, FLE design has evolved from extra-large vascular plug through physician modified version, to different iterations of a custom-made, self-occluding endografts. This manuscript summarizes the evolution of false lumen occluders, characteristics of the last generation of the device and currently available literature clinical experience.</p>}},
  author       = {{Berczeli, Márton and Sonesson, Björn and Mogensen, John and Karelis, Angelos and Dias, Nuno V}},
  issn         = {{0021-9509}},
  keywords     = {{Humans; Aortic Dissection/surgery; Endovascular Procedures/instrumentation; Blood Vessel Prosthesis Implantation/instrumentation; Blood Vessel Prosthesis; Chronic Disease; Prosthesis Design; Treatment Outcome; Aortic Aneurysm, Thoracic/surgery; Stents}},
  language     = {{eng}},
  number       = {{3}},
  pages        = {{218--226}},
  publisher    = {{Edizioni Minerva Medica S.p.A.}},
  series       = {{The Journal of cardiovascular surgery}},
  title        = {{The current false lumen endograft and clinical experience for false lumen occlusion in chronic aortic dissection}},
  url          = {{http://dx.doi.org/10.23736/S0021-9509.25.13356-9}},
  doi          = {{10.23736/S0021-9509.25.13356-9}},
  volume       = {{66}},
  year         = {{2025}},
}