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Vaccination and allergy : EAACI position paper, practical aspects

Nilsson, Lennart; Brockow, Knut; Alm, Johan; Cardona, Victoria; Caubet, Jean Christoph; Gomes, Eva; Jenmalm, Maria C.; Lau, Susanne; Netterlid, Eva LU and Schwarze, Jürgen, et al. (2017) In Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 28(7). p.628-640
Abstract

Immunization is highly effective in preventing infectious diseases and therefore an indispensable public health measure. Allergic patients deserve access to the same publicly recommended immunizations as non-allergic patients unless risks associated with vaccination outweigh the gains. Whereas the number of reported possible allergic reactions to vaccines is high, confirmed vaccine-triggered allergic reactions are rare. Anaphylaxis following vaccination is rare, affecting <1/100 000, but can occur in any patient. Some patient groups, notably those with a previous allergic reaction to a vaccine or its components, are at heightened risk of allergic reaction and require special precautions. Allergic reactions, however, may occur in... (More)

Immunization is highly effective in preventing infectious diseases and therefore an indispensable public health measure. Allergic patients deserve access to the same publicly recommended immunizations as non-allergic patients unless risks associated with vaccination outweigh the gains. Whereas the number of reported possible allergic reactions to vaccines is high, confirmed vaccine-triggered allergic reactions are rare. Anaphylaxis following vaccination is rare, affecting <1/100 000, but can occur in any patient. Some patient groups, notably those with a previous allergic reaction to a vaccine or its components, are at heightened risk of allergic reaction and require special precautions. Allergic reactions, however, may occur in patients without known risk factors and cannot be predicted by currently available tools. Unwarranted fear and uncertainty can result in incomplete vaccination coverage for children and adults with or without allergy. In addition to concerns about an allergic reaction to the vaccine itself, there is fear that routine childhood immunization may promote the development of allergic sensitization and disease. Thus, although there is no evidence that routine childhood immunization increases the risk of allergy development, such risks need to be discussed.

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Contribution to journal
publication status
published
subject
keywords
Adjuvant, Adverse event, Allergy, Anaphylaxis, Vaccination
in
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology
volume
28
issue
7
pages
628 - 640
publisher
Wiley-Blackwell
external identifiers
  • scopus:85031118328
  • wos:000418437400003
ISSN
0905-6157
DOI
10.1111/pai.12762
language
English
LU publication?
yes
id
aa0f19ec-544d-4b1d-94fc-031fbf3a4740
date added to LUP
2017-11-07 15:54:12
date last changed
2018-11-21 21:35:54
@article{aa0f19ec-544d-4b1d-94fc-031fbf3a4740,
  abstract     = {<p>Immunization is highly effective in preventing infectious diseases and therefore an indispensable public health measure. Allergic patients deserve access to the same publicly recommended immunizations as non-allergic patients unless risks associated with vaccination outweigh the gains. Whereas the number of reported possible allergic reactions to vaccines is high, confirmed vaccine-triggered allergic reactions are rare. Anaphylaxis following vaccination is rare, affecting &lt;1/100 000, but can occur in any patient. Some patient groups, notably those with a previous allergic reaction to a vaccine or its components, are at heightened risk of allergic reaction and require special precautions. Allergic reactions, however, may occur in patients without known risk factors and cannot be predicted by currently available tools. Unwarranted fear and uncertainty can result in incomplete vaccination coverage for children and adults with or without allergy. In addition to concerns about an allergic reaction to the vaccine itself, there is fear that routine childhood immunization may promote the development of allergic sensitization and disease. Thus, although there is no evidence that routine childhood immunization increases the risk of allergy development, such risks need to be discussed.</p>},
  author       = {Nilsson, Lennart and Brockow, Knut and Alm, Johan and Cardona, Victoria and Caubet, Jean Christoph and Gomes, Eva and Jenmalm, Maria C. and Lau, Susanne and Netterlid, Eva and Schwarze, Jürgen and Sheikh, Aziz and Storsaeter, Jann and Skevaki, Chrysanthi and Terreehorst, Ingrid and Zanoni, Giovanna},
  issn         = {0905-6157},
  keyword      = {Adjuvant,Adverse event,Allergy,Anaphylaxis,Vaccination},
  language     = {eng},
  number       = {7},
  pages        = {628--640},
  publisher    = {Wiley-Blackwell},
  series       = {Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology},
  title        = {Vaccination and allergy : EAACI position paper, practical aspects},
  url          = {http://dx.doi.org/10.1111/pai.12762},
  volume       = {28},
  year         = {2017},
}