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Measuring activities of daily living in Parkinson's disease : On a road to nowhere and back again?

Hagell, Peter LU (2019) In Measurement: Journal of the International Measurement Confederation 132. p.109-124
Abstract

Parkinson's disease (PD) is a progressive neurodegenerative disorder associated with increasing disability and limitations in performance of activities of daily living (ADL) despite availability of effective symptomatic therapy. Following an overview of classical test theory (CTT) and Rasch measurement theory (RMT), the case of a clinical PD trial aiming to demonstrate ADL improvements by using the ADL section (part II) of the Unified PD Rating Scale (UPDRS) to measure ADL outcomes is considered and central questions related to its validity and interpretation are addressed. It is found that while CTT did not detect any issues, RMT in combination with conceptual considerations seriously challenged the role of the UPDRS II as an ADL... (More)

Parkinson's disease (PD) is a progressive neurodegenerative disorder associated with increasing disability and limitations in performance of activities of daily living (ADL) despite availability of effective symptomatic therapy. Following an overview of classical test theory (CTT) and Rasch measurement theory (RMT), the case of a clinical PD trial aiming to demonstrate ADL improvements by using the ADL section (part II) of the Unified PD Rating Scale (UPDRS) to measure ADL outcomes is considered and central questions related to its validity and interpretation are addressed. It is found that while CTT did not detect any issues, RMT in combination with conceptual considerations seriously challenged the role of the UPDRS II as an ADL outcome measure. Results are discussed from historical, methodological and clinical perspectives.

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author
organization
publishing date
type
Contribution to journal
publication status
published
subject
keywords
Activities of daily living, Classical test theory, Outcome measurement, Parkinson's disease, Rasch measurement theory, Rating scales
in
Measurement: Journal of the International Measurement Confederation
volume
132
pages
16 pages
publisher
Elsevier
external identifiers
  • scopus:85053775599
ISSN
0263-2241
DOI
10.1016/j.measurement.2018.09.050
language
English
LU publication?
yes
id
ab499f1f-b05e-474c-a3d2-8cb47d4a22ca
date added to LUP
2018-10-08 09:46:58
date last changed
2019-09-17 04:40:02
@article{ab499f1f-b05e-474c-a3d2-8cb47d4a22ca,
  abstract     = {<p>Parkinson's disease (PD) is a progressive neurodegenerative disorder associated with increasing disability and limitations in performance of activities of daily living (ADL) despite availability of effective symptomatic therapy. Following an overview of classical test theory (CTT) and Rasch measurement theory (RMT), the case of a clinical PD trial aiming to demonstrate ADL improvements by using the ADL section (part II) of the Unified PD Rating Scale (UPDRS) to measure ADL outcomes is considered and central questions related to its validity and interpretation are addressed. It is found that while CTT did not detect any issues, RMT in combination with conceptual considerations seriously challenged the role of the UPDRS II as an ADL outcome measure. Results are discussed from historical, methodological and clinical perspectives.</p>},
  author       = {Hagell, Peter},
  issn         = {0263-2241},
  keyword      = {Activities of daily living,Classical test theory,Outcome measurement,Parkinson's disease,Rasch measurement theory,Rating scales},
  language     = {eng},
  month        = {01},
  pages        = {109--124},
  publisher    = {Elsevier},
  series       = {Measurement: Journal of the International Measurement Confederation},
  title        = {Measuring activities of daily living in Parkinson's disease : On a road to nowhere and back again?},
  url          = {http://dx.doi.org/10.1016/j.measurement.2018.09.050},
  volume       = {132},
  year         = {2019},
}