Infection dynamics of the tick-borne pathogen 'Candidatus Neoehrlichia mikurensis' and co-infections with Borrelia afzelii in bank voles in Southern Sweden.
(2014) In Applied and Environmental Microbiology 80(5). p.1645-1649- Abstract
- The tick-borne bacterium 'Candidatus Neoehrlichia mikurensis' has recently been recognized as a human pathogen. Together with Borrelia afzelii, it is one of the most common pathogens found in the tick Ixodes ricinus. Here, we compared the epidemiology of 'Candidatus N. mikurensis' and B. afzelii by longitudinal sampling from May to September in one of their most abundant vertebrate hosts, the bank vole (Myodes glareolus), using real-time PCR for detection and quantification. The prevalence of 'Candidatus N. mikurensis' and B. afzelii was 19% (50/261) and 22% (56/261), respectively. The prevalence of 'Candidatus N. mikurensis' increased significantly during the sampling season. The clearance rate of 'Candidatus N. mikurensis' was... (More)
- The tick-borne bacterium 'Candidatus Neoehrlichia mikurensis' has recently been recognized as a human pathogen. Together with Borrelia afzelii, it is one of the most common pathogens found in the tick Ixodes ricinus. Here, we compared the epidemiology of 'Candidatus N. mikurensis' and B. afzelii by longitudinal sampling from May to September in one of their most abundant vertebrate hosts, the bank vole (Myodes glareolus), using real-time PCR for detection and quantification. The prevalence of 'Candidatus N. mikurensis' and B. afzelii was 19% (50/261) and 22% (56/261), respectively. The prevalence of 'Candidatus N. mikurensis' increased significantly during the sampling season. The clearance rate of 'Candidatus N. mikurensis' was significantly higher than that of B. afzelii. We found a high frequency of double infections; 46% of all samples infected with 'Candidatus N. mikurensis' also had a co-infection with B. afzelii. The frequency of co-infections was significantly higher than expected from the prevalence of each pathogen. The high level of co-infections can be caused by interactions between the pathogens or might reflect variation in general susceptibility among voles. (Less)
Please use this url to cite or link to this publication:
https://lup.lub.lu.se/record/4292371
- author
- Andersson, Martin LU ; Scherman, Kristin LU and Råberg, Lars LU
- organization
- publishing date
- 2014
- type
- Contribution to journal
- publication status
- published
- subject
- in
- Applied and Environmental Microbiology
- volume
- 80
- issue
- 5
- pages
- 1645 - 1649
- publisher
- American Society for Microbiology
- external identifiers
-
- pmid:24375128
- wos:000331626300013
- scopus:84894088670
- pmid:24375128
- ISSN
- 0099-2240
- DOI
- 10.1128/AEM.03469-13
- project
- Borrelia in rodents
- language
- English
- LU publication?
- yes
- id
- ab51fab8-77b9-4261-a2d9-18f50f0bcc80 (old id 4292371)
- date added to LUP
- 2016-04-01 11:11:08
- date last changed
- 2022-04-28 07:55:22
@article{ab51fab8-77b9-4261-a2d9-18f50f0bcc80,
abstract = {{The tick-borne bacterium 'Candidatus Neoehrlichia mikurensis' has recently been recognized as a human pathogen. Together with Borrelia afzelii, it is one of the most common pathogens found in the tick Ixodes ricinus. Here, we compared the epidemiology of 'Candidatus N. mikurensis' and B. afzelii by longitudinal sampling from May to September in one of their most abundant vertebrate hosts, the bank vole (Myodes glareolus), using real-time PCR for detection and quantification. The prevalence of 'Candidatus N. mikurensis' and B. afzelii was 19% (50/261) and 22% (56/261), respectively. The prevalence of 'Candidatus N. mikurensis' increased significantly during the sampling season. The clearance rate of 'Candidatus N. mikurensis' was significantly higher than that of B. afzelii. We found a high frequency of double infections; 46% of all samples infected with 'Candidatus N. mikurensis' also had a co-infection with B. afzelii. The frequency of co-infections was significantly higher than expected from the prevalence of each pathogen. The high level of co-infections can be caused by interactions between the pathogens or might reflect variation in general susceptibility among voles.}},
author = {{Andersson, Martin and Scherman, Kristin and Råberg, Lars}},
issn = {{0099-2240}},
language = {{eng}},
number = {{5}},
pages = {{1645--1649}},
publisher = {{American Society for Microbiology}},
series = {{Applied and Environmental Microbiology}},
title = {{Infection dynamics of the tick-borne pathogen 'Candidatus Neoehrlichia mikurensis' and co-infections with Borrelia afzelii in bank voles in Southern Sweden.}},
url = {{http://dx.doi.org/10.1128/AEM.03469-13}},
doi = {{10.1128/AEM.03469-13}},
volume = {{80}},
year = {{2014}},
}