Lund University Publications

@article{ac0b72f4-bc11-4d75-92c3-e66f7b3bac76,
  abstract     = {{<p>Introduction – Adolescent depression poses a major public health concern with substantial clinical and societal implications. Both internet-delivered cognitive behavioural therapy (ICBT) and internet-delivered psychodynamic therapy (IPDT) have shown efficacy, but questions remain regarding long-term efficacy and cost-effectiveness. The present study presents a 12-month follow-up and cost-comparison from a randomized controlled trial (RCT) comparing ICBT and IPDT for adolescent depression. Methods – Participants were 272 adolescents aged 15–19 with a primary diagnosis of major depressive disorder. The primary outcome was depressive symptoms measured with the QIDS-A17-SR while the secondary outcome was anxiety symptoms measured with the GAD-7. Costs were assessed both by comparing costs of treatment and healthcare use 12-month post-treatment using the TIC-P. Results – Results were stable at the 12-month follow up compared to treatment endpoint, for both depressive and anxiety symptoms. There were no significant group differences at the 12-month follow-up. There were no differences in treatment costs or in costs for healthcare use one-year post-treatment. Discussion – This study suggests that treatment gains from IPDT and ICBT for adolescent depression remain stable during a 12-month follow-up period, with no differences between the treatments one-year post-treatment. Furthermore, it suggests comparable costs for the treatments. Interpretation of health-care use data was restricted due to the COVID-19 pandemic taking place during the follow-up period. This adds to the literature suggesting that ICBT and IPDT can be seen as viable alternatives for treating adolescent depression. More research into the long-term effects and cost-effectiveness is needed.</p>}},
  author       = {{Lindqvist, Karin and Mechler, Jakob and Peristera, Paraskevi and Carlbring, Per and Falkenström, Fredrik and Lilliengren, Peter and Andersson, Gerhard and Johansson, Robert and Midgley, Nick and Edbrooke-Childs, Julian and Dahl, Hanne Sofie J. and Sandell, Rolf and Thorén, Agneta and Topooco, Naira and Ulberg, Randi and Lindert Bergsten, Katja and Philips, Björn}},
  issn         = {{1664-0640}},
  keywords     = {{adolescent depression; CBT; cost-analysis; follow-up; internet-delivered treatment; PDT; RCT}},
  language     = {{eng}},
  publisher    = {{Frontiers Media S. A.}},
  series       = {{Frontiers in Psychiatry}},
  title        = {{Twelve-month outcomes and comparative costs of internet-delivered psychodynamic therapy versus cognitive-behavioral therapy for adolescent depression : a randomized controlled trial}},
  url          = {{http://dx.doi.org/10.3389/fpsyt.2026.1794684}},
  doi          = {{10.3389/fpsyt.2026.1794684}},
  volume       = {{17}},
  year         = {{2026}},
}